胰岛素降解酶(IDE)单克隆抗体
Monoclonal Antibody to Insulin Degrading Enzyme (IDE)
Insulysin; Insulin Protease; Abeta-degrading protease; Insulinase
- 编号MAB897Hu22
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)C2
- Ig亚型 IgG1 Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原 RPB897Hu01-胰岛素降解酶(IDE)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性状液体
- 浓度0.8mg/mL
- 且适物种-
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 634 ¥ 1478 ¥ 2112 ¥ 5280 ¥ 21120
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对IDE的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别IDE。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunofluorescence:5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
RPB897Hu01 | 胰岛素降解酶(IDE)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB897Hu01 | 胰岛素降解酶(IDE)多克隆抗体 | WB; IHC |
MAB897Hu21 | 胰岛素降解酶(IDE)单克隆抗体 | WB; IHC; ICC; IP. |
MAB897Hu22 | 胰岛素降解酶(IDE)单克隆抗体 | WB; IHC; ICC; IP. |
SEB897Hu | 胰岛素降解酶(IDE)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB897Hu | 胰岛素降解酶(IDE)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
KSB897Hu01 | 胰岛素降解酶(IDE)检测试剂盒DIY材料(酶联免疫吸附试验法) | 自己动手制作ELISA试剂盒的主要材料 |
参考文献
杂志 | 参考文献 |
J Neurochem | Reduction [PubMed: 26442993] |
African Journal of Pharmacy and Pharmacology | Peptide hydroxamate derivatives as regulators for insulin receptor signaling and its degradation by zinc metalloprotease in diabetic rats [article-full-text-pdf] |
Biomedicine & Pharmacotherapy | Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylationin diabetic rats. [pubmed:27930980] |
Biological Trace Element Research | Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats [10.1007/s12011-017-1167-z] |
Neuroscience | The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A [Pubmed:29406271] |
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