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突触核蛋白α(SNCa)多克隆抗体(生物素标记)

Biotin-Linked Polyclonal Antibody to Synuclein Alpha (SNCa)

SNC-A; aSYN; PD1; PARK1; PARK4; NACP; Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein; Non-A4 component of amyloid precursor

  • 突触核蛋白α(SNCa)多克隆抗体(生物素标记) 产品包装(模拟)
  • 突触核蛋白α(SNCa)多克隆抗体(生物素标记) 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对SNCa的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别SNCa。

用法

Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
RPB222Hu01 突触核蛋白α(SNCa)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAB222Hu01 突触核蛋白α(SNCa)多克隆抗体 WB; IHC; ICC; IP.
LAB222Hu71 突触核蛋白α(SNCa)多克隆抗体(生物素标记) WB; IHC; ICC.
MAB222Hu22 突触核蛋白α(SNCa)单克隆抗体 WB; IHC; ICC; IP.
SEB222Hu 突触核蛋白α(SNCa)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
AEB222Hu 抗突触核蛋白α抗体(Anti-SNCa)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antibody Detection.

参考文献

杂志 参考文献
The Journal of Clinical Investigation Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration [PubMed: PMC3428100]
Neurobiology of Disease Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission [PubMed: PMC3107939]
Nature Communications Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus [PubMed: PMC3265381]
Provisional chapter Mutations of PARK Genes and Alpha-Synuclein and Parkin Concentrations in Parkinson’s Disease [Intechopen:Source]
Nerodegeneration Apolipoprotein Eε4: A Biomarker for Executive Dysfunction among Parkinson's Disease Patients with Mild Cognitive Impairment [pubmed:29326545]
Experimental gerontology The anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling. [pubmed:29107062]
Neurobiology of Disease Development and biochemical characterization of a mouse model of Parkinson's disease bearing defective glucocerebrosidase activity [Pubmed: 30521842]
molecular and cellular biochemistry Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model [Pubmed: 31820278]
International Journal of Pharmacology Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease [Pubmed: 32084576]
EBioMedicine Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys [Pubmed: 32810825]
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