趋化因子C-X3-C-基元配体1(CX3CL1)真核蛋白
Eukaryotic Chemokine C-X3-C-Motif Ligand 1 (CX3CL1)
NTN; ABCD3; C3Xkine; CXC3; CXC3C; NTT; SCYD1; ABCD3; FKN; Neurotactin; Fractalkine; Small Inducible Cytokine Subfamily D(Cys-X3-Cys)Member 1
- 编号EPA040Mu61
- 物种Mus musculus (Mouse，小鼠) 相同的名称，不同的物种。
- 来源真核表达
- 宿主293F cell
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜, 分泌
- 预测分子量27.8kDa
- 实际分子量60kDa(差异分析请参阅说明书)
- 片段与标签Gln83~Pro330 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 95%
- 等电点4.2
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1368 ¥ 3420 ¥ 6840 ¥ 20520 ¥ 51300
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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Figure. SDS-PAGE
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Mus musculus (Mouse，小鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA040Mu02 | 趋化因子C-X3-C-基元配体1(CX3CL1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA040Mu61 | 趋化因子C-X3-C-基元配体1(CX3CL1)活性蛋白 | Cell culture; Activity Assays. |
| EPA040Mu61 | 趋化因子C-X3-C-基元配体1(CX3CL1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA040Mu01 | 趋化因子C-X3-C-基元配体1(CX3CL1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA040Mu01 | 趋化因子C-X3-C-基元配体1(CX3CL1)多克隆抗体 | WB; IHC; ICC; IP. |
| PAA040Mu02 | 趋化因子C-X3-C-基元配体1(CX3CL1)多克隆抗体 | WB; IHC; ICC; IP. |
| SEA040Mu | 趋化因子C-X3-C-基元配体1(CX3CL1)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA040Mu | 趋化因子C-X3-C-基元配体1(CX3CL1)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMA040Mu | 趋化因子C-X3-C-基元配体1(CX3CL1)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| World Journal of Gastroenterology | Preliminary study correlating CX3CL1/CX3CR1 expression with gastric carcinoma and gastric carcinoma perineural invasion [NCBI: PMC3989981] |
| International Journal of Colorectal Disease | Downregulation of CX3CR1 ameliorates experimental colitis: evidence for CX3CL1-CX3CR1-mediated immune cell recruitment. [pubmed:27942903] |
| Frontiers in Cellular and Infection Microbiology | Reduced CX3CL1 Secretion Contributes to the Susceptibility of Oral Leukoplakia-Associated Fibroblasts to Candida albicans. [pubmed:27891323] |
| Blood Coagul Fibrinolysis | Low shear stress upregulates the expression of fractalkine through the activation of mitogen-activated protein kinases in endothelial cells [Pubmed:29406386] |
| Journal of Neuroinflammation | The prenatal challenge with lipopolysaccharide and polyinosinic: polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of … [Pubmed: 32829711] |
| Cells | Maternal Immune Activation Sensitizes Male Offspring Rats to Lipopolysaccharide-Induced Microglial Deficits Involving the Dysfunction of CD200–CD200R and … [Pubmed: 32664639] |
| Journal of Neuroinflammation | CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats [Pubmed: 32532282] |
| JOURNAL OF PERIODONTAL RESEARCH | Potential biomarkers reflecting inflammation in patients with severe periodontitis: Fractalkine (CX3CL1) and its receptor (CX3CR1) [33641164] |
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