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胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法)

Multiplex Assay Kit for Caspase 3 (CASP3) ,etc. by FLIA (Flow Luminescence Immunoassay)

CPP32; CPP32B; SCA1; Apoptain; Yama; Apoptosis-Related Cysteine Peptidase; Cysteinyl Aspartate Specific Proteinases 3; SREBP cleavage activity 1

(注:单次混测多因子不超过8个指标 )

  • 胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法) 产品包装(模拟)
  • 胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法) 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

本试剂盒用于检测胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法),经检测与其它相似物质无明显交叉反应。
由于受到技术及样本来源的限制,不可能完成对所有相关或相似物质交叉反应检测,因此本试剂盒有可能与未经检测的其它物质有交叉反应。

回收率

分别于定值血清及血浆样本中加入一定量的胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法)(加标样品),重复测定并计算其均值,回收率为测定值与理论值的比率。

样本 回收率范围(%) 平均回收率(%)
serum(n=5) 80-102 85
EDTA plasma(n=5) 97-104 101
heparin plasma(n=5) 83-101 96
sodium citrate plasma(n=5) 97-105 102

精密度

精密度用样品测定值的变异系数CV表示。CV(%) = SD/mean×100
批内差:取同批次试剂盒对低、中、高值定值样本进行定量检测,每份样本连续测定20 次,分别计算不同浓度样本的平均值及SD值。
批间差:选取3个不同批次的试剂盒分别对低、中、高值定值样本进行定量测定,每个样本使用同一试剂盒重复测定8次,分别计算不同浓度样本的平均值及SD值。
批内差: CV<10%
批间差: CV<12%

线性

在定值血清及血浆样本内加入适量的胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法),并倍比稀释成1:2,1:4,1:8,1:16的待测样本,线性范围即为稀释后样本中胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法)含量的测定值与理论值的比率。

样本 1:2 1:4 1:8 1:16
serum(n=5) 92-101% 85-95% 85-99% 83-101%
EDTA plasma(n=5) 86-103% 96-103% 99-105% 79-89%
heparin plasma(n=5) 78-91% 85-96% 98-105% 89-96%
sodium citrate plasma(n=5) 90-97% 92-99% 85-98% 86-101%

稳定性

经测定,试剂盒在有效期内按推荐温度保存,其活性降低率小于5%。
为减小外部因素对试剂盒破坏前后检测值的影响,实验室的环境条件需尽量保持一致,尤其是实验室内温度、湿度及温育条件。其次由同一实验员来进行操作可减少人为误差。

实验流程

1. 实验前标准品、试剂及样本准备;
2. 加样(标准品、样本、磁珠)标准品或样本100μL及磁珠10μL,
    37°C酶标板振荡器孵育90分钟;
3. 磁吸甩干,加检测溶液A100μL,37°C酶标板振荡器孵育60分钟;
4. 磁吸洗板3次;
5. 加检测溶液B100μL,37°C振动孵育30分钟;
6. 磁吸洗板3次;
7. 加鞘液100μL,旋涡震荡2分钟后读数。

实验原理

将胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法)抗体包被于磁珠,制成固相载体,向微孔中分别加入标准品或标本以及磁珠,其中的胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法)与连接于固相载体上的抗体结合,然后加入生物素化的胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法)抗体,将未结合的生物素化抗体洗净后,加入PE标记的亲和素,再次彻底洗涤后即可上机读数。MFI值和样品中的胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法)呈正相关。

赠品

相关产品

编号 适用物种:Homo sapiens (Human,人) 应用(仅供研究使用,不用于临床诊断!)
APA626Hu01 胱天蛋白酶3(CASP3)活性蛋白 Cell culture; Activity Assays.
RPA626Hu01 胱天蛋白酶3(CASP3)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA626Hu02 胱天蛋白酶3(CASP3)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA626Hu03 胱天蛋白酶3(CASP3)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA626Hu03 胱天蛋白酶3(CASP3)多克隆抗体 WB; IHC; ICC; IP.
PAA626Hu02 胱天蛋白酶3(CASP3)多克隆抗体 WB,IHC
PAA626Hu01 胱天蛋白酶3(CASP3)多克隆抗体 WB; IHC; ICC; IP.
LAA626Hu81 胱天蛋白酶3(CASP3)多克隆抗体(异硫氰酸荧光素标记) WB; IHC; ICC; IF.
LAA626Hu71 胱天蛋白酶3(CASP3)多克隆抗体(生物素标记) WB; IHC; ICC.
MAA626Hu21 胱天蛋白酶3(CASP3)单克隆抗体 WB; IHC; ICC; IP.
MAA626Hu22 胱天蛋白酶3(CASP3)单克隆抗体 WB; IHC; ICC; IP.
SEA626Hu 胱天蛋白酶3(CASP3)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA626Hu 胱天蛋白酶3(CASP3)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.
KSA626Hu01 胱天蛋白酶3(CASP3)检测试剂盒DIY材料(酶联免疫吸附试验法) Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志 参考文献
International Journal of Biological Sciences Protective Effects of Morus alba Leaves Extract on Ocular Functions of Pups from Diabetic and Hypercholesterolemic Mother Rats [PubMed: 21697998]
Reprod Sci. Role of mitochondria in ciprofloxacin-induced apoptosis in murine sperm cells. [Pubmed: 23420823]
European journal of pharmacology The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats [Pubmed: 23845213]
Journal of Physiology and Biochemistry Vitamin D ameliorates hepatic ischemic/reperfusion injury in rats [Springer: Source]
Life Sci. Attenuation of renal ischemia/reperfusion injury by a?aí extract preconditioning in a rat model [Pubmed:25476829]
Toxicol Appl Pharmacol.? Amelioration of nandrolone decanoate-induced testicular and sperm toxicity in rats by taurine: Effects on steroidogenesis, redox and inflammatory cascades, and intrinsic apoptotic pathway [Pubmed:25542992]
Journal of Traditional and Complementary Medicine Antioxidant effects of Spirulina supplement against lead acetate-induced hepatic injury in rats [Sciencedirect:S2225411015000231]
J Physiol Biochem. Vitamin D ameliorates hepatic ischemic/reperfusion injury in rats [Pubmed:24752458]
Molecular Biology Reports Apoptotic effects of dipyrido [3,2-a:2',3'-c] phenazine (dppz) Au(III) complex against diethylnitrosamine/phenobarbital induced experimental hepatocarcinogenesis in rats [Pubmed:24756331]
Life Sciences Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats [Pubmed:25010842]
European Journal of Pharmacology Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in rats [Pubmed:25084223]
J Investig Clin Dent. Expression of key executioner of apoptosis caspase?\3 in periodontal health and disease [Pubmed:25388853]
Neuropharmacology Saxagliptin: A novel antiparkinsonian approach [Pubmed:25446674]
Molecular Neurobiology Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson’s Disease: Modulation of Mitochondrial Perturbations [Pubmed:25502462]
Histochem Cell Biol. Inhibition of small HA fragment activity and stimulation of A2A adenosine receptor pathway limit apoptosis and reduce cartilage damage in experimental arthritis [Pubmed:25511416]
Protective role of ellagitannins from Eucalyptus citriodora against ethanol-induced gastric ulcer in rats: Impact on oxidative stress, inflammation and calcitonin-gene related peptide [Pubmed:25636864]
Biochemical Pharmacology Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study [Pubmed:25701654]
Journal of Pharmacology Research CILOSTAZOL HEPATOPROTECTIVE EFFECT AGAINST ISCHEMIA/REPERFUSION: INVOLVEMENT OF GSK-3β, CYCLIN D1 and WNT/β-CATENIN PATHWAY [Researchgate:Source]
Life Sciences Attenuation of renal ischemia/reperfusion injury by a [PubMed: 25476829]
Injury Neuroprotective [PubMed: 26298021]
PLOS ONE Antidiabetic Effect of Galantamine: Novel Effect for a Known Centrally Acting Drug [PubMed: 26262991]
Histochem Cell Biol Inhibition of small HA fragment activity and stimulation of A2A [PubMed: 25511416]
PLOS ONE BDNF-TrkB Pathway Mediates Neuroprotection of Hydrogen Sulfide against Formaldehyde-Induced Toxicity to PC12 Cells [PubMed: 25749582]
Life Sci Geraniol ameliorates TNBS-induced colitis: Involvement of Wnt/棺-catenin, p38MAPK, NF觀B, and PPAR款 signaling pathways [PubMed: 26165751]
Naunyn Schmiedebergs Arch Pharmacol The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis [PubMed: 26269412]
Pharmacological Reports The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice [Science: Article]
European Journal of Medicinal Plants Hepatoprotective Effects of Rubus idaeus L. Leaves against CCl4-Induced Liver Injury via Antioxidant, Anti-inflammatory and Antiapoptotic Mechanisms [openview:626440]
Chemico-Biological Interactions Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-reCavia (Guinea pig )lation of inflammatory and apoptic pathways [Pubmed:26807765]
Oncotarget An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimers mouse model [Pubmed:27144524]
Journal of Food Science Correlation of In Vivo and In Vitro Assay Results for Assessment of Free Radical Scavenging Activity of Green Tea Nutraceuticals [Pubmed:27275932]
Journal of Natural Medicines Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark of Lycium chinense (Cortex Lycii) against gastric ulcer in mice [Pubmed:26972100]
Iranian Journal of Basic Medical Sciences Neuroprotective effects of atomoxetine against traumatic spinal cord injury in rats [pmc:PMC4834117]
IJBPAS THE PROPHYLACTIC EFFICIENCY OF LYCOPENE AGAINST GAMMA IRRADAITION-INDIUCED CARDIAC OXIDATIVE DAMAGE, PATHOLOGY AND APOPTOSIS IN RATS [publication:298838934]
Neurochem Res. Arecoline Induces Neurotoxicity to PC12 Cells: Involvement in ER Stress and Disturbance of Endogenous H2S Generation [Pubmed:27255601]
Original Investigation Neuroprotective Effects of Pregabalin Against Spinal Cord Ischemia-Reperfusion Injury in Rats [JTNEPUB:17959]
Molecules Clematichinenoside (AR) Attenuates Hypoxia/Reoxygenation-Induced H9c2 Cardiomyocyte Apoptosis via a Mitochondria-Mediated Signaling Pathway [Pubmed:27248986]
Springerplus. The hepatocurative effects of Cynara scolymus L. leaf extract on carbon tetrachloride-induced oxidative stress and hepatic injury in rats [Pubmed:27026910]
Oncotarget Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE−/− alzheimer mouse model [pubmed:27708245]
Journal of traditional and complementary medicine. Antioxidant effects of Spirulina supplement against lead acetate-induced hepatic injury in rats. [pubmed:27774414]
pharmaceutical biology Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice. [pubmed:28064632]
Toxicology and Applied Pharmacology Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins [pubmed:27687055]
Journal of Natural Medicines Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark ofLycium chinense (Cortex Lycii) against gastric ulcer in mice. [pubmed:26972100]
BMC Cancer Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent andmitochondrial pathways in mammalian hepatic stellate cells. [pubmed:27461108]
Neurochemical Research Arecoline Induces Neurotoxicity to PC12 Cells: Involvement in ER Stress and Disturbance of Endogenous H2S Generation. [pubmed:27255601]
Molecular Medicine Reports Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting the expression of peroxiredoxin III in H9c2 cells [mmr:13]
The American Journal of Chinese Medicine Saikosaponin a Induces Apoptosis through Mitochondria-Dependent Pathway in Hepatic Stellate Cells [pubmed:28231747]
bmc musculoskeletal disorders Strontium ranelate causes osteophytes overgrowth in a model of early phase osteoarthritis. [pubmed:28187731]
Journal of Ethnopharmacology Amelioration of cardiac dysfunction and ventricular remodeling after myocardial infarction bydanhong injection are critically contributed by anti-TGF-β-mediated fibrosis and angiogenesis mechanisms. [pubmed:27729285]
Food and Chemical Toxicology Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats [pubmed:29247772]
Journal of Molecular Biomarkers J & Diagnosis Role of Pomegranate Juice and Atorvastatin in Ameliorating Spinal Neurotoxicity of Wistar Rats Maternally Fed on Hypercholesterolemic Diet [DOI: 10.4172/2155-9929.1000316]
Cellular Physiology and Biochemistry A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats [pubmed:28942443]
International Journal of Biological Macromolecules A polysaccharide (PNPA) from Pleurotus nebrodensis ameliorates hepatic ischemic/reperfusion (I/R) injury in rats [pubmed:28709897]
Experimental and Therapeutic Medicine Tectorigenin attenuates the MPP+ induced SH‑SY5Y cell damage, indicating a potential beneficial role in Parkinson's disease by oxidative stress inhibition [pubmed:29067118]
Biomedical Research Pitavastatin inhibits proinflammatory cytokines and provides improvement in terms of its motor function in secondary injuries of the spinal cord mouse models [ISSN 0970-938X]
Chemico-Biological Interactions Modulatory effect of silymarin on nuclear factor-erythroid-2-related factor 2 regulated redox status, nuclear factor-κB mediated inflammation and apoptosis in experimental gastric ulcer [10.1016/j.cbi.2017.06.022]
Frontiers in Pharmacology Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus. [pubmed:28553224]
Journal of Inorganic Biochemistry Biomimetic fabrication of antibacterial calcium phosphates mediated by polydopamine. [pubmed:29049953]
Indian Journal of Pharmaceutical Sciences Hepatoprotective Activities of the Methanol Extract of Angelica shikokiana and Isoepoxypteryxin against Hepatocellular Carcinoma [DOI: 10.4172/pharmaceutical-sciences.1000265]
Theranostics Drug-delivering-drug platform-mediated potent protein therapeutics via a non-endo-lysosomal route [Pubmed:30026860]
Food and Chemical Toxicology Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin–induced diabetic rats [Pubmed:30026088]
Life Sciences Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects [Pubmed:30012474]
Journal of Ethnopharmacology Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells [Pubmed:29555410]
Journal of Medicinal Food Posttreatment Effects of L. Leaf Extract on Carbon Tetrachloride-Induced Liver Injury and Oxidative Stress in Rats [Pubmed:29648970]
Reproductive Biology Anti-hypercholesterolemic impacts of barley and date palm fruits on the ovary of Wistar albino rats and their offspring [Pubmed:30005909]
BMC Pharmacology and Toxicology Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis [Pubmed:29321061]
Toxics Zinc Oxide Nanoparticles Induced Oxidative DNA Damage, Inflammation and Apoptosis in Rat's Brain after Oral Exposure [Pubmed:29861430]
Avicenna Journal of Medical Biotechnology Apoptosis of Adipose-Derived Stem Cells Induced by Liposomal Soybean Phosphatidylcholine Extract [Pubmed:30090204]
Biological Trace Element Research Effect of Aqueous Extract of Glycyrrhiza glabra on the Biochemical Changes Induced by Cadmium Chloride in Rats [Pubmed: 30251228]
Environmental Toxicology Potential immunomodulatory and antioxidant effects of walnut  vegetable oil against lead‐mediated hepatic damage and their interaction with lipase … [Pubmed: 30251767]
Life Sciences Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats [Pubmed: 30205096]
AAPS PharmSciTech Augmentation of Fluvastatin Cytotoxicity Against Prostate Carcinoma PC3 Cell Line Utilizing Alpha Lipoic–Ellagic Acid Nanostructured Lipid Carrier Formula [Pubmed: 30350252]
Naunyn-Schmiedeberg's Archives of Pharmacology Side effects of frequently used oral antidiabetics on wound healing in vitro [Pubmed: 30535571]
Archives of Physiology and Biochemistry Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin [Pubmed: 30513216]
Acta Biochimica et Biophysica Sinica Adiponectin attenuates lipopolysaccharide-induced cell injury of H9c2 cells by regulating AMPK pathway [Pubmed: 30668810]
Food and Chemical Toxicology Gum Acacia mitigates diclofenac nephrotoxicity by targeting monocyte chemoattractant protein-1, complement receptor-1 and pro-apoptotic pathways [Pubmed: 31042592]
Environmental Toxicology Antihepatocarcinogenic activity of whey protein concentrate and lactoferrin in diethylnitrosamine‐treated male albino mice [Pubmed: 31087429]
Biological trace element research High Concentrations of Boric Acid Trigger Concentration-Dependent Oxidative Stress, Apoptotic Pathways and Morphological Alterations in DU-145 Human Prostate … [Pubmed: 31066018]
Skin pharmacology and physiology Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro [Pubmed: 31018213]
Iranian Journal of Pharmaceutical Research Therapeutic effects of nano-HAp in a rat model of AlCl3 induced neurotoxicity [Doi: 10.22037/IJPR.2019.1100760]
International Journal of Pharmaceutical Research & Allied Sciences Prophylactic Impact of Beta vulgaris L in Ameliorating Cyclosporine A-Induced Hepatotoxicity in Rats. []
Effect of gamma radiation on combination therapy of certain antiepileptic drugs in rats. []
Journal of Food Biochemistry Dietary supplementation of barley and/or dates attenuate hypercholesterolemic‐induced endometrial dysfunction in Wistar albino rats via alleviation of apoptotic … [Pubmed: 31373029]
Antioxidants (Basel). The Effect of Dietary Quercetin on the Glutathione Redox System and Small Intestinal Functionality of Weaned Piglets [Pubmed: 31426309]
Biological Trace Element Research The Role of Oxidative Stress, Renal Inflammation, and Apoptosis in Post Ischemic Reperfusion Injury of Kidney Tissue: the Protective Effect of Dose-Dependent Boric … []
Cell Stress Chaperones Betaine suppresses cell proliferation by increasing oxidative stress–mediated apoptosis and inflammation in DU-145 human prostate cancer cell line [Pubmed: 31368044]
Int Immunopharmacol Metallothionein-1 is associated with osteoarthritis disease activity and suppresses proinflammatory cytokines production in synovial cells [Pubmed: 31465913]
Biological trace element research Concentration-Dependent Effects of Zinc Sulfate on DU-145 Human Prostate Cancer Cell Line: Oxidative, Apoptotic, Inflammatory, and Morphological Analyzes [Pubmed: 31463762]
Naunyn-Schmiedeberg's Archives of Pharmacology Carnosine and l-arginine attenuate the downregulation of brain monoamines and gamma aminobutyric acid; reverse apoptosis and upregulate the expression of … [Pubmed: 31641819]
Antioxidants Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin–Induced Diabetic Rats: Combined Protective Effects of Malaysian … [Pubmed: 31600920]
International Journal of Molecular Sciences Encapsulation of Lovastatin in Zein Nanoparticles Exhibits Enhanced Apoptotic Activity in HepG2 Cells [Pubmed: 31752085]
Scientific Reports Mebendazole augments sensitivity to sorafenib by targeting MAPK and BCL-2 signalling in n-nitrosodiethylamine-induced murine hepatocellular carcinoma [Pubmed: 31836811]
Pharmaceutics Preparation and Optimization of In Situ Gel Loaded with Rosuvastatin-Ellagic Acid Nanotransfersomes to Enhance the Anti-Proliferative Activity [Pubmed: 32183144]
Photodiagnosis and Photodynamic Therapy In vitro evaluation of cytotoxic properties of 5-Aminolevulinic acid (5-ALA) on bladder cancer cells [Pubmed: 32165337]
Frontiers in Neuroscience Hydrogen Sulfide Prevents Sleep Deprivation-Induced Hippocampal Damage by Upregulation of Sirt1 in the Hippocampus [Pubmed: 32218719]
FASEB J Bovine colostrum induces the differentiation of human primary keratinocytes [Pubmed: 32157742]
Marine Drugs In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma [Pubmed: 32283782]
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY Effects of repeated increasing doses of cisplatin as models of acute kidney injury and chronic kidney disease in rats [Pubmed: 32936352]
Pharmaceutics Chitosan-Based Microparticles Enhance Ellagic Acid's Colon Targeting and Proapoptotic Activity [Pubmed: 32660035]
Life Sciences Curcumin and LOXblock-1 ameliorate ischemia-reperfusion induced inflammation and acute kidney injury by suppressing the semaphorin-plexin pathway. [Pubmed: 32603817]
TOXICOLOGY Tert-butylhydroquinone preserve testicular steroidogenesis and spermatogenesis in cisplatin-intoxicated rats by targeting oxidative stress, inflammation and apoptosis [Pubmed: 32565124]
International Journal of Molecular Sciences Optimized Conjugation of Fluvastatin to HIV-1 TAT Displays Enhanced Pro-Apoptotic Activity in HepG2 Cells [Pubmed: 32531976]
analytical chemistry Fast Activation and Tracing of Caspase-3 Involved Cell Apoptosis by Combined Electrostimulation and Smart Signal-Amplified SERS Nanoprobes [Pubmed: 32395992]
Mar Drugs Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity [Pubmed: 32344610]
BIOMEDICINE & PHARMACOTHERAPY Protective effects of bee bread on testicular oxidative stress, NF-κB-mediated inflammation, apoptosis and lactate transport decline in obese male rats [Pubmed: 33152939]
Iranian Journal of Basic Medical Sciences Chromon-3-aldehyde derivatives restore mitochondrial function in rat cerebral ischemia [Pubmed: 32963739]
International Journal of Research in Pharmaceutical In situ gel loaded with curcumin-based fluvastatin nanostructured carrier effective against squamous tongue carcinoma []
SAGE Journals Insights Into Protective Mechanisms of Dandelion Leaf Extract Against Cisplatin-Induced Nephrotoxicity in Rats: Role of Inhibitory Effect on Inflammatory and Apoptotic … []
Bangladesh Journal of Pharmacology Ethylmethylhydroxypyridine succinate, acetylcysteine and choline alphoscerate improve mitochondrial function under condition of cerebral ischemia in rat []
International Journal of Pharmacology Ellagic Acid Loaded TPGS Micelles for Enhanced Anticancer Activities in Ovarian Cancer []
Strawberry (Fragaria x ananassa) leaf extract reduces brain damage in diabetic male rats []
Indian Journal of Animal Research Accacia senegel extract ameliorates Lead Acetate-mediated Hepatotoxicity in rats. []
RESEARCH SQUARE Experimental Observation of the Sequence of Tibial Plateau Chondrocyte and Matrix Degeneration in Spontaneous Osteoarthritis in Guinea Pigs []
Egyptian Journal of Basic and Applied Sciences Fish-oil supplementation improves retinal injury induced by diabetes and hypercholesterolemia in male Wistar rats []
ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES []
Norwegian Journal of development of the International Science CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER []
J Biochem Mol Toxicol Concanavalin A induces apoptosis in a dose©\dependent manner by modulating thiol/disulfide homeostasis in C6 glioblastoma cells [33604990]
International Journal of Reproductive Medicine Gonadotropin Stimulation Has Only a Limited Effect on the Concentration of Follicular Fluid Signalling Proteins: An Antibody Array Analysis [33575317]
Sci Rep Tert-butylhydroquinone attenuates doxorubicin-induced dysregulation of testicular cytoprotective and steroidogenic genes, and improves spermatogenesis in rats [33750916]
TOXICOLOGY IN VITRO Cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of SIRT1 in C6 glioblastoma cells [33675893]
Biomed Pharmacother Captopril downregulates expression of Bax/cytochrome C/caspase-3 apoptotic pathway, reduces inflammation, and oxidative stress in cisplatin-induced acute?¡­ [33945910]
Reprod Sci Reproductive Effects of Nicotinamide on Testicular Function and Structure in Old Male Rats: Oxidative, Apoptotic, Hormonal, and Morphological Analyses [34101148]
BMC Complement Med Ther Effect of the standard herbal preparation, STW5, treatment on dysbiosis induced by dextran sodium sulfate in experimental colitis [34103031]
Environ Sci Pollut Res Int Comparative effects of metformin and Cistus laurifolius L. extract in streptozotocin-induced diabetic rat model: oxidative, inflammatory, apoptotic, and histopathological?¡­ [34097215]
Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NF¦ÊB Axis. Front. Pharmacol. 11: 614897. doi?¡­ [33519479]
Biomed Pharmacother Allicin ameliorates renal ischemia/reperfusion injury via inhibition of oxidative stress and inflammation in rats [34426252]
Chem Biol Interact Protective role of naringin loaded solid nanoparticles against aflatoxin B1 induced hepatocellular carcinoma [34717916]
Biochim Biophys Acta Gen Subj Paraoxonase 2 protects against the CML mediated mitochondrial dysfunction through modulating JNK pathway in human retinal cells [34710487]
AAPS PharmSciTech Development of an Icariin-Loaded Bilosome-Melittin Formulation with Improved Anticancer Activity against Cancerous Pancreatic Cells [34668089]
Analytical Cellular Pathology The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia [34336554]
Ecotoxicol Environ Saf Evaluation of cytogenotoxic potential and embryotoxicity of KRS-Cauvery River water in zebrafish (Danio rerio) [Pubmed:35183813]
Environ Sci Pollut Res Int Chrysin attenuates estradiol-induced endometrial hyperplasia in rats via enhancing PPARα activity [Pubmed:35301625]
PLoS One Neuroprotective effect of sodium alginate against chromium-induced brain damage in rats [Pubmed:35421180]
Journal of Ethnopharmacology Ethnopharmacological impact of Melaleuca rugulosa (Link) Craven leaves extract on liver inflammation [Pubmed:35337921]
Eur J Pharmacol Harmine prevents 3-nitropropionic acid-induced neurotoxicity in rats via enhancing NRF2-mediated signaling: Involvement of p21 and AMPK [Pubmed:35623405]
Gels QbD Supported Optimization of the Alginate-Chitosan Nanoparticles of Simvastatin in Enhancing the Anti-Proliferative Activity against Tongue Carcinoma [Pubmed:35200484]
Naunyn-Schmiedeberg's Archives Inflammatory Modulation of miR-155 Inhibits Doxorubicin‑Induced Testicular Dysfunction Via Sirt1/Foxo1 Pathway: Insight to the Role of Acacetin and Bacillus … [Pubmed:35715546]
Antioxidants Therapeutic Effects of Bee Bread on Obesity-Induced Testicular-Derived Oxidative Stress, Inflammation, and Apoptosis in High-Fat Diet Obese Rat Model … [Pubmed:35204140]
Value Health Sci Oksidatif, Apoptotik ve İnflamatuar Sinyal Yolakları üzerinden C6 Glioblastoma Hücrelerindeki ML351'in Antiproliferatif Etkileri []
Impact de l'incorporation d'acides gras à chaine moyenne, de suppléments de levures et d'avoine nue sur la santé intestinale ainsi que sur la consommation … []
Biointerface Research in Applied Chemistry Promising Therapeutic Efficacy of Trigonella-foenum graecum and Bone Marrow-Derived Mesenchymal Stem Cells on Skeletal Muscle Atrophy in Experimental … []
Arab Journal of Nuclear Sciences and Applications Potential activity of silver/hydroxyapatite nano composite against damaged liver consequence to irradiation []
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