血管紧张素转化酶2(ACE2)重组蛋白
Recombinant Angiotensin I Converting Enzyme 2 (ACE2)
ACEH; ACEII; ACE-II; Peptidyl-Dipeptidase A; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; Metalloprotease MPROT15
- 编号RPB886Hu02
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量87.3kDa
- 实际分子量87kDa(差异分析请参阅说明书)
- 片段与标签Gln18~Ser740 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300)
- 性状冻干粉
- 纯度> 90%
- 等电点5.6
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1075 ¥ 2688 ¥ 5376 ¥ 16128 ¥ 40320
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
EPB886Hu61 | 血管紧张素转化酶2(ACE2)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APB886Hu01 | 血管紧张素转化酶2(ACE2)活性蛋白 | Cell culture; Activity Assays. |
APB886Hu61 | 血管紧张素转化酶2(ACE2)活性蛋白 | Cell culture; Activity Assays. |
RPB886Hu01 | 血管紧张素转化酶2(ACE2)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB886Hu02 | 血管紧张素转化酶2(ACE2)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB886Hu01 | 血管紧张素转化酶2(ACE2)多克隆抗体 | WB; IHC; ICC; IP. |
MAB886Hu23 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
MAB886Hu24 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
MAB886Hu25 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
MAB886Hu21 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC |
MAB886Hu22 | 血管紧张素转化酶2(ACE2)单克隆抗体 | WB; IHC; ICC; IP. |
FAB886Hu08 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
FAB886Hu04 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
FAB886Hu02 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
FAB886Hu06 | 抗血管紧张素转化酶2(ACE2)单克隆抗体 | Flow cytometry. |
SEB886Hu | 血管紧张素转化酶2(ACE2)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
AEB886Hu | 抗血管紧张素转化酶2抗体(Anti-ACE2)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antibody Detection. |
LMB886Hu | 血管紧张素转化酶2(ACE2)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Nature Medicine | Angiotensin-Converting Enzyme 2 Overexpression Remarkably Ameliorated Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition [MolMed: 10_11_liu] |
Journal of Cancer Therapy | Plasma Levels of Angiotensin-Converting Enzymes 1 and 2 and AGTR2 (T1247G and A5235G) Gene Polymorphisms Are Associated to Breast Cancer Progression. [Scirp: Source] |
Reprod Toxicol.? | ACE2 activation by xanthenone prevents leptin-induced increases in blood pressure and proteinuria during pregnancy in Sprague-Dawley rats [Pubmed:25205467] |
Intensive Care Medicine Experimental | Angiotensin converting enzymes in patients with acute respiratory distress syndrome [Content: 3] |
Journal of Chromatography A | Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis [S0021967317311858] |
Journal of Clinical Pharmacy and Therapeutics | Relationship between genetic variants of ACE2 gene and circulating levels of ACE2 and its metabolites. [pubmed:28895159] |
Innate Immunity | Lipoxin A attenuates LPS-induced acute lung injury via activation of the ACE2-Ang-(1-7)-Mas axis [Pubmed:29969931] |
Journal of Surgical Research | Impact of angiotensin-converting enzyme 2 levels on postoperative pneumonia after esophagectomy [Pubmed:29506841] |
canadian journal of physiology and pharmacology | Could cardioprotective effect of ACE2 activator “diminazene aceturate” is more potent than ACE inhibitor “Enalapril” on acute myocardial infarction in rats? [Pubmed: 30840489] |
Intensive Care Medicine | Angiotensin-converting enzymes in acute respiratory distress syndrome [] |
BioMed Research International | AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway [] |
Heart and vessels | Relationship between circulating levels of angiotensin-converting enzyme 2-angiotensin-(1–7)-MAS axis and coronary heart disease [Pubmed: 31359146] |
Medicine | Alteration and association between serum ACE2/angiotensin (1-7)/Mas axis and oxidative stress in chronic kidney disease: A pilot study [Pubmed: 32756181] |
American Journal of Respiratory and Critical Care Medicine | Equilibrium Angiotensin Metabolite Profiling in Patients with Acute Respiratory Distress Syndrome Indicates Angiotensin Converting Enzyme Inhibition [Pubmed: 32628511] |
Clinical Research in Cardiology | Determinants of soluble angiotensin-converting enzyme 2 concentrations in adult patients with complex congenital heart disease [33280062] |
Clinical & Translational Immunology | Pattern of circulating SARS©\CoV©\2©\specific antibody©\secreting and memory B©\cell generation in patients with acute COVID©\19 [33552508] |
researchsquare | Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis [33855640] |
Viruses | Different Neutralization Sensitivity of SARS-CoV-2 Cell-to-Cell and Cell-Free Modes of Infection to Convalescent Sera [] |
Sci Rep | Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury [34907257] |
European Journal of Clinical Investigation | Angiotensin‐converting enzyme 2 and Transmembrane protease serine 2 in female and male patients with end‐stage kidney disease [Pubmed:35366343] |
Metabolites | Ramipril Reduces Acylcarnitines and Distinctly Increases Angiotensin-Converting Enzyme 2 Expression in Lungs of Rats [Pubmed:35448480] |
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