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铁调素(Hepc)真核蛋白

Eukaryotic Hepcidin (Hepc)

HAMP; HFE2B; PLTR; LEAP1; Hepcidin Antimicrobial Peptide; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor

  • 铁调素(Hepc)真核蛋白 产品包装(模拟)
  • 铁调素(Hepc)真核蛋白 产品包装(模拟)
  • 铁调素(Hepc)真核蛋白 Figure . Gene Sequencing (extract)
  • EPB979Hu61.jpg Figure. SDS-PAGE
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

序列

用法

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
EPB979Hu61 铁调素(Hepc)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPB979Hu01 铁调素(Hepc)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
APB979Hu61 铁调素(Hepc)活性蛋白 Cell culture; Activity Assays.
CPB979Hu12 铁调素(Hepc)牛血清白蛋白偶联物 Immunogen; SDS-PAGE; WB.
CPB979Hu22 铁调素(Hepc)卵白蛋白偶联物 Immunogen; SDS-PAGE; WB.
CPB979Hu23 铁调素(Hepc)卵白蛋白偶联物 Immunogen; SDS-PAGE; WB.
CPB979Hu21 铁调素(Hepc)卵白蛋白偶联物 Immunogen; SDS-PAGE; WB.
PAB979Hu07 铁调素(Hepc)多克隆抗体 WB; IHC; ICC; IP.
PAB979Hu09 铁调素(Hepc)多克隆抗体 WB; IHC; ICC; IP.
PAB979Hu06 铁调素(Hepc)多克隆抗体 WB; IHC; ICC; IP.
PAB979Hu01 铁调素(Hepc)多克隆抗体 WB; IHC; ICC; IP.
PAB979Hu08 铁调素(Hepc)多克隆抗体 WB; IHC; ICC; IP.
LAB979Hu81 铁调素(Hepc)多克隆抗体(异硫氰酸荧光素标记) WB; IHC; ICC; IF.
LAB979Hu71 铁调素(Hepc)多克隆抗体(生物素标记) WB; IHC; ICC.
MAB979Hu26 铁调素(Hepc)单克隆抗体 WB
MAB979Hu22 铁调素(Hepc)单克隆抗体 WB; IHC; ICC; IP.
MAB979Hu21 铁调素(Hepc)单克隆抗体 IHC.
RAB979Hu21 铁调素(Hepc)重组抗体 WB; IF; ICC; IHC; IP; FCM.
SEB979Hu 铁调素(Hepc)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
CEB979Hu 铁调素(Hepc)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB979Hu 铁调素(Hepc)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
CCB979Hu 铁调素(Hepc)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
LMB979Hu 铁调素(Hepc)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.
KSB979Hu11 铁调素(Hepc)检测试剂盒DIY材料(酶联免疫吸附试验法) Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志 参考文献
World J Gastroenterol. Hepcidin expression in colon during trinitrobenzene sulfonic acid-induced colitis in rats [Pubmed: 24764672]
International Journal of Advanced Research Modulations of serum hepcidin, IL6 and iron status by different exercise regimens in ovarectomized rats [Com:Source]
Neurochemical Journal Serum iron metabolism markers including hepcidin in multiple sclerosis patients [Springer:Source]
Afro-Egypt J Infect Endem Dis Monitoring Hepcidin Level in Chronic Hepatitis C Virus Patients during Therapy [Zu:Source]
Gastroenterology Gluconeogenic signals regulate iron homeostasis via hepcidin in mice [Pubmed:Pmc3989026]
J Card Fail. Inappropriate expression of hepcidin by liver congestion contributes to anemia and relative iron deficiency [Pubmed:24440572]
Food Funct. The action of JAK, SMAD and ERK signal pathways on hepcidin suppression by polysaccharides from Angelica sinensis in rats with iron deficiency anemia [Pubmed:24752529]
Free Radic Res. Changes in skeletal muscle iron metabolism outpace amyotrophic lateral sclerosis onset in transgenic rats bearing the G93A hmSOD1 gene mutation [Pubmed:25175826]
Saudi J Kidney Dis Transpl. Hepcidin and regulation of iron homeostasis in maintenance hemodialysis patients [Pubmed:25193892]
J Endocrinol Invest.? The interplay among iron metabolism, endothelium and inflammatory cascade in dysmetabolic disorders [Pubmed:25245337]
Gastroenterology Research and Practice An Evaluation of the Correlation between Hepcidin Serum Levels and Disease Activity in Inflammatory Bowel Disease [Pubmed:25628652]
Clin Lab. Serum hepcidin levels in Bulgarian population. [Pubmed:25651734]
The Tohoku Journal of Experimental Medicine Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia [Pubmed:25742771]
Cancer Res Hepcidin regulation in prostate and its disruption in prostate cancer [PubMed: 25858146]
Biochem Biophys Res Commun B-cell translocation gene 2 promotes hepatic hepcidin production via induction of Yin Yang 1 [PubMed: 25839654]
Blood Purif Effect of a More Permeable Dialysis Membrane on ESA Resistance in Hemodialysis Patients - A Pilot Investigation [PubMed: 26536083]
Asian Journal of Clinical Nutrition Urinary Hepcidin in Diagnosis of Iron Deficiency Anemia [Openview: E01Ad7C4A9109Ed5Fadb03Ec206D7Bdc]
Front Psychol Ferrous sulfate, but not iron polymaltose complex, aggravates local and systemic inflammation and oxidative stress in dextran sodium sulfate-induced colitis in rats [PubMed: 25852597]
Biol Trace Elem Res Iron Supplementation Attenuates the Inflammatory Status of Anemic Piglets by Regulating Hepcidin [PubMed: 25774043]
APS Journals Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal copper, high fructose diet in male rats. [PubMed: 25813056]
European Journal of Haematology Hepcidin in tumor‐related iron deficiency anemia and tumor‐related anemia of chronic disease: pathogenic mechanisms and diagnosis [PubMed: 24954786]
WJA The Effects of Treatment on Serum Hepcidin and Iron Homeostasis in HIV-1-Infected In-dividuals [Journal: 59107]
Nutrition, Metabolism and Cardiovascular Diseases Hepcidin and iron metabolism associated with cardiometabolic risk factors in children: A case-control study. [Pubmed:27139516]
Food Funct The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice [Pubmed:26757699]
Antioxid Redox Signal. Hydrogen sulfide attenuates inflammatory hepcidin by reducing IL-6 secretion and promoting SIRT1-mediated STAT3 deacetylation [Pubmed:26154696]
BioMed Research International The Impact of Acute Matriptase Inhibition in Hepatic Inflammatory Models. [pubmed:27642598]
Frontiers in Neuroscience In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution. [pubmed:27729845]
Experimental Biology and Medicine Effects of iron supplementation in mice with hypoferremia induced by obesity [pubmed:27439539]
Nutrition, Metabolism and Cardiovascular Diseases Hepcidin and iron metabolism associated with cardiometabolic risk factors in children: A case–control study [pubmed:27139516]
PLOS ONE S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory Hepcidin and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway. [pubmed:27649298]
Endocrine connections Hepcidin links gluco-toxicity to pancreatic beta cell dysfunction by inhibiting Pdx-1 expression [pubmed:28179377]
Maternal and cord blood hepcidin levels based on gestational weeks in term and preterm infants [publication:305921433_Maternal_and_cord_blood_hepc]
Oxidative Medicine and Cellular Longevity Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation [pubmed:29147463]
The Royal Society of Chemistry Silkworm feces extract improves iron deficiency anemia via suppressing hepcidin expression and promoting iron-regulatory proteins expression [DOI: 10.1039/C7RA09576G]
Journal of Inflammation Evaluation of a competitive hepcidin ELISA assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients [10.1186:s12950-017-0166-3]
Antioxidants and Redox Signaling AMPK serves as a Therapeutic Target against Anemia of Inflammation [pubmed:27923278]
NutriciónHospitalaria Micronutrient supplementation in gastric bypass surgery: prospective study on infl ammation and iron metabolism in premenopausal women [10.20960/nh.1162]
The Japanese Society of Hematology Hepcidin suppression in β‑thalassemia is associated with the down‑regulation of atonal homolog 8 [pubmed:28405918]
Tuberculosis Modulation of iron status biomarkers in tuberculosis-diabetes co-morbidity [10.1016/j.tube.2017.11.011]
Oman Medical Journal The Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus. [pubmed:28584599]
Cellular Physiology and Biochemistry The Effects of Angelica Sinensis Polysaccharide on Tumor Growth and Iron Metabolism by Regulating Hepcidin in Tumor-Bearing Mice [Pubmed:29843136]
Cellular Microbiology  inhibits ferroportin translation by modulating FBXL5‐IRP2 axis for its growth within host macrophages [Pubmed:29470856]
Journal of Histochemistry & Cytochemistry Acute and Chronic Iron Overloading Differentially Modulates the Expression of Cellular Iron-homeostatic Molecules in Normal Rat Kidney [Pubmed:29873589]
Clinical and Experimental Medicine Increased NGAL level associated with iron store in chronic kidney disease with anemia [Pubmed:29909502]
Hematology Relationship between obesity and iron deficiency anemia: is there a role of hepcidin? [Pubmed:29318945]
Hepcidin serum levels in HCV chronically mono-infected naïve patients, compared to healthy individuals [77856]
Food & Function Effect of iron supplement from microalgae on the treatment of iron-deficient anemia in rats [Doi: 10.1039/C8FO01696H]
Haematologica New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and β-thalassemia [Pubmed: 30792208]
Ann Intensive Care Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study [Pubmed: 31183575]
Journal of Functional Foods Dietary gelatin enhances non-heme iron absorption possibly via regulation of systemic iron homeostasis in rats []
Naunyn Schmiedebergs Arch Pharmacol. 3-Amidinophenylalanine-derived matriptase inhibitors can modulate hepcidin production in vitro [Pubmed: 31659405]
DEVELOPMENT GROWTH & DIFFERENTIATION H2O2 induces oxidative stress damage through the BMP‐6/SMAD/hepcidin axis [Pubmed: 32012242]
Frontiers in Physiology Increased Hepcidin Levels During a Period of High Training Load Do Not Alter Iron Status in Male Elite Junior Rowers [Pubmed: 32038278]
J Korean Med Sci Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients? [Pubmed: 32174062]
nephrology dialysis transplantation Iron kinetics following treatment with sucroferric oxyhydroxide or ferric citrate in healthy rats and models of anaemia, iron overload or inflammation [Pubmed: 32259248]
mikrochimica acta Gold-silver core-shell nanoparticle–based impedimetric immunosensor for detection of iron homeostasis biomarker hepcidin [Pubmed: 33095336]
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY Circulating Osteocyte‐Related Biomarkers (vitamin D, sclerostin, dickkopf-1), hepcidin, and oxidative stress markers in early breast cancer: their impact in … [Pubmed: 33065276]
Sleep Breath Relation of serum hepcidin levels and restless legs syndrome in chronic hemodialysis patients [Pubmed: 33029690]
journal of trace elements in experimental medicine Difference in iron metabolism may partly explain sex-related variability in the manifestation of Wilson's disease [Pubmed: 32937238]
reproduction in domestic animals Expression of iron regulatory proteins in full term swine placenta [Pubmed: 32449967]
Neurobiology of Aging Estrogen deficiency is associated with brain iron deposition via upregulation of hepcidin expression in aged female mice [Pubmed: 32920472]
The Egyptian Journal of Haematology Urinary hepcidin concentration in assessment of iron homeostasis in pediatrics []
COMPARATIVE MONITORING OF THE ENZYME ACTIVITY OF BONE METABOLISM IN PATIENTS AFTER DENTAL IMPLANTATION []
Serum iron, prealbumin, D-dimer and prothrombin time are indicators of the diagnosis, severity and outcome of Salmonella enterica serovar Enteritidis infection []
Гепсидин и индекс фиброза печени MELD-XI как маркеры полиорганной недостаточности у пациентов хронической сердечной недостаточностью с … []
Ассоциации уровней NT-proBNP и гепсидина с клинико-лабораторными параметрами у больных хронической сердечной недостаточностью с разной … []
Biosci Rep Correlation of hepcidin and serum ferritin levels in thalassemia patients at Chiang Mai University Hospital [33565577]
Biometals Iron metabolism is disturbed and anti-copper treatment improves but does not normalize iron metabolism in Wilson's disease [33555495]
J Mol Cell Cardiol Systemic iron deficiency does not affect the cardiac iron content and progression of heart failure [34139233]
Continuous Veno-Venous Hemofiltration (CVVH) Improves Iron Metabolism Disorders in Patients With Sepsis: A Single-Center Prospective Cohort Study []
Reports of Biochemistry & Molecular Biology Evaluation of Serum Cyclooxygenase, Hepcidin Levels in Acute Renal Injury (AKI) Patients Following Cardiac Catheterization []
Food Funct High-dose ferric citrate supplementation attenuates omega-3 polyunsaturated fatty acid biosynthesis via downregulating delta 5 and 6 desaturases in rats with high-fat … [34787162]
J Trace Elem Med Biol Caffeine and alcohol-friends or foes of human iron stores? [Pubmed:35063815]
PeerJ Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis [Pubmed:35698613]
Serum Calprotectin and Iron Metabolism Biomarker Levels in Behçet's Disease []
Food Bioscience Roles of homopolymeric apoferritin in alleviating alcohol-induced liver injury []
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