单核细胞趋化蛋白1(MCP1)重组蛋白
Recombinant Monocyte Chemotactic Protein 1 (MCP1)
CCL2; GDCF2; HC11; HSMCR30; MCAF; MCP1; SCYA2; SMC-CF; Chemokine C-C-Motif Ligand 2; Monocyte Chemotactic And Activating Factor; Monocyte Secretory Protein JE
- 编号RPA087Mi02
- 物种Mus musculus (Mouse,小鼠) 相同的名称,不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位n/a
- 预测分子量-
- 实际分子量-(差异分析请参阅说明书)
- 片段与标签N-terminal His Tag
- 缓冲液成份磷酸盐缓冲液(pH7.4,含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.)
- 性状冻干粉
- 纯度> 97%
- 等电点-
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
序列
用法
PBS或其它。
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
编号 | 适用物种:Mus musculus (Mouse,小鼠) | 应用(仅供研究使用,不用于临床诊断!) |
RPA087Mi02 | 单核细胞趋化蛋白1(MCP1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
SEA087Mi | 单核细胞趋化蛋白1(MCP1)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
WEA087Mi | 单核细胞趋化蛋白1(MCP1)检测试剂盒(酶联免疫吸附试验法,宽范围) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA087Mi | 单核细胞趋化蛋白1(MCP1)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Cytokine | Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression. [Pubmed: 23434274] |
Rheumatology International | Serum levels of selected chemokines in systemic lupus erythematosus patients [Pubmed: 22461186] |
Food & Function | Effects of Hyriopsis cumingii polysaccharides on angiogenesis, macrophage chemotaxis, proliferation and phagocytosis [Pubmed:25620195] |
36 | MRTF-A steers an epigenetic complex to activate endothelin-induced pro-inflammatory transcription in vascular smooth muscle cells [Pubmed:Pmc4176337] |
Journal of Trace Elements in Medicine and Biology | Adipose tissue chromium and vanadium disbalance in high-fat fed Wistar rats [Pubmed:25194956] |
天津中医药大学学报 | 巨噬细胞及其相关因子在家兔不稳定斑块中的作用及其机制 [Paper:Source] |
Int J Clin Exp Pathol | Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitis [PubMed: 26191125] |
Mediators of Inflammation | Effects of Intravenous Injection of [PubMed: 26063970] |
Diabetes | Protein Inhibitor of Activated STAT 1 (PIAS1) Protects Against Obesity-Induced Insulin Resistance by Inhibiting Inflammation Cascade in Adipose Tissue [PubMed: 26324179] |
Journal of Histochmistry and Cytochmistry | Epigallocatechin-3-Gallate Attenuates Unilateral Ureteral Obstruction-Induced Renal Interstitial Fibrosis in Mice [PubMed: 25549657] |
Cell Physiol Biochem | MicroRNA-155 Promotes Atherosclerosis Inflammation via Targeting SOCS1 [PubMed: 26159489] |
Exp Biol Med (Maywood) | Renoprotective effects of angiotensin receptor blocker and stem cells in acute kidney injury: Involvement of inflammatory and apoptotic markers [PubMed: 25825359] |
Parasitol Res | Trypanosoma cruzi infection and benznidazole therapy independently stimulate oxidative status and structural pathological remodeling of the liver tissue in mice [PubMed: 25912691] |
Invest Ophthalmol Vis Sci | Simultaneous Increase in Multiple Proinflammatory Cytokines in the Aqueous Humor in Neovascular Glaucoma With and Without Intravitreal Bevacizumab Injection [PubMed: 26030108] |
PLoS One | Postoperative changes in aqueous monocyte chemotactic protein-1 levels and bleb morphology after trabeculectomy vs. Ex-PRESS shunt surgery [PubMed: 26427058] |
Veterinary Parasitology | Expression of adhesion molecules, chemokines and matrix metallo- proteinases (MMPs) in viable and degenerating stage of Taenia solium metacestode in swine neurocysticercosis [PubMed: 26412140] |
J Pharm Pharmacol | Modulation of oxidative and inflammatory cardiac response by nonselective 1‐and 3‐cyclooxygenase inhibitor and benznidazole in mice [PubMed: 26105112] |
Микроэлементы в медицине | НАРУШЕНИЕ БАЛАНСА ХРОМА И ВАНАДИЯ В ЖИРОВОЙ ТКАНИ КАК ВОЗМОЖНЫЙ МЕХАНИЗМ ОЖИРЕНИЕ-АССОЦИИРОВАННОЙ ИНСУЛИНОРЕЗИСТЕНТНОСТИ [Microelements_Of_Midicine: 2015_2] |
Front Pharmacol | The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling Pathway [PubMed: 26696888] |
PLoS One | Effects of PB-EPCs on Homing Ability of Rabbit BMSCs via Endogenous SDF-1 and MCP-1. [PubMed: 26660527] |
Scientific Reports | The Transcriptional Foundations of Sp110-mediated Macrophage (RAW264. 7) Resistance to Mycobacterium tuberculosis H37Ra [Pubmed:26912204] |
Neural Plasticity | Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress [Pubmed:27239349] |
Technologia Alimentaria | Decreased adipose tissue zinc content is associated with metabolic parameters in high fat fed Wistar rats [abstract:10] |
International Immunopharmacology | Consistency and pathophysiological characterization of a rat polymicrobial sepsis model via the improved cecal ligation and puncture surgery [Pubmed:26802602] |
J Neurochem. | Anti‐inflammatory properties of tianeptine on lipopolysaccharide‐induced changes in microglial cells involve toll‐like receptor‐related pathways [Pubmed:26640965] |
Oxidative Medicine and Cellular Longevity | Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation. [pubmed:27656261] |
Comparative Clinical Pathology | Identification of some plasma biomarkers associated with early weaning stress in crossbred piglets [article:10.1007] |
clinical chemistry and laboratory medicine | The serum concentrations of leptin and MCP-1 independently predict low back pain duration. [pubmed:28076310] |
Journal of Molecular Cell Biology | oxLDL antibody inhibits MCP‐1 release in monocytes/macrophages by regulating Ca2+/K+ channel flow [pubmed:27995732] |
Parasitology. | Nonsteroidal anti-inflammatory is more effective than anti-oxidant therapy in counteracting oxidative/nitrosative stress and heart disease in T. cruzi-infected mice. [pubmed:28134069] |
Experimental Parasitology | Adhesion molecules, chemokines and matrix metallo-proteinases response after albendazole and albendazole plus steroid therapy in swine neurocysticercosis [pubmed:28821422] |
National Natural Scientific | Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas after Chronic Alcohol Exposure [pubmed:29121396] |
Evidence-Based Complementary and Alternative Medicine | BuShenKangShuai tablet reduces atherosclerotic lesion by improving blood lipids metabolism and inhibiting inflammatory response via TLR4 and NF-κB signaling pathway [journals:1758383] |
International Journal of Clinical and Experimental Pathology | Protective effect of high mobility group box-1 silence on diabetic retinopathy: an in vivo study [ISSN:1936-2625/IJCEP0055881] |
Nature Medicine | An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury. [pubmed:29227475] |
Redox Biology | STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO2 gradient. [pubmed:29078168] |
Nature Medicine | The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis [Pubmed:29291351] |
NPG Asia Materials | Molybdenum disulfide/graphene oxide nanocomposites show favorable lung targeting and enhanced drug loading/tumor-killing efficacy with improved … [Articles:am2017225] |
Clinical Science | Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity [Pubmed:29382697] |
Life Sciences | Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation [Pubmed:29499280] |
Evidence-based Complementary and Alternative Medicine | Bushenkangshuai Tablet Reduces Atherosclerotic Lesion by Improving Blood Lipids Metabolism and Inhibiting Inflammatory Response via TLR4 and NF-κB Signaling … [Pubmed:29619063] |
Lasers in Medical Science | Evaluation of the therapeutic effect of micro-plasma radio frequency on hypertrophic scars in rabbit ears [Pubmed:30003425] |
Journal of Ocular Pharmacology and Therapeutics | Effect of 0.05% Difluprednate Ophthalmic Emulsion on Proinflammatory Cytokine Levels After Retinal Laser Photocoagulation in Rabbits [Pubmed:29812993] |
Journal of Interferon & Cytokine Research | Increased Serum MCP-1 Levels in Systemic Vasculitis Patients with Renal Involvement [Pubmed: 30230985] |
Prostaglandins & Other Lipid Mediators | Detoxification and activating blood circulation decoction reduces restenosis involving the TLR4/NF-κB pathway after balloon injury [Pubmed: 30453089] |
Molecular Neurobiology | Role of Chronic Administration of Antidepressant Drugs in the Prenatal Stress-Evoked Inflammatory Response in the Brain of Adult Offspring Rats … [Pubmed: 30610610] |
Journal Of Clinical Investigation | Long non-coding RNA mitigates atherosclerosis by regulating the actin-binding protein NEXN [Pubmed: 30589415] |
Kidney International | Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndrome [Pubmed: 30770217] |
Biosensors and Bioelectronics | A sensitive sandwich-type immunosensor for the detection of MCP-1 based on a rGO-TEPA-Thi-Au nanocomposite and novel RuPdPt trimetallic nanoalloy particles [] |
European Journal of Pharmacology | The cordycepin derivative IMM-H007 improves endothelial dysfunction by suppressing vascular inflammation and promoting AMPK-dependent eNOS activation in … [Pubmed: 30826323] |
Experimental and Therapeutic Medicine | Effect of stress hyperglycaemia on monocyte chemoattractant protein‑1 levels and the short‑term prognosis of patients with acute ST‑segment elevation myocardial … [] |
Hepatology | Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in Mice [Pubmed: 31077413] |
FASEB Journal | Rescuing cones and daylight vision in retinitis pigmentosa mice [Pubmed: 31199887] |
Metallomics | Lanthanum chloride induces neuron damage by activating the nuclear factor-kappa B signaling pathway in activated microglia [Pubmed: 31187842] |
Hepatology | Hepatocyte TRAF 6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lys6‐Linked Polyubiquitination of ASK 1 [] |
journal of cellular and molecular medicine | LncRNA HOXA11‐AS regulates calcium oxalate crystal–induced renal inflammation via miR‐124‐3p/MCP‐1 [Pubmed: 31680444] |
Diabetes | Histone H3 serine 10 phosphorylation facilitates endothelial activation in diabetic kidney disease [Pubmed: 30213824] |
Biomedicine & Pharmacotherapy | Inhibition of CXCL1-CXCR2 axis ameliorates cisplatin-induced acute kidney injury by mediating inflammatory response [Pubmed: 31812015] |
ACTA PHARMACOLOGICA SINICA | α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice [Pubmed: 32973325] |
EBioMedicine | Modulating endothelial adhesion and migration impacts stem cell therapies efficacy [Pubmed: 32942121] |
PHARMACOLOGICAL RESEARCH | Sea cucumbers-derived sterol sulfate alleviates insulin resistance and inflammation in high-fat-high-fructose diet-induced obese mice [Pubmed: 32911073] |
BRITISH JOURNAL OF PHARMACOLOGY | A novel apoA‐I mimetic peptide suppresses atherosclerosis by promoting physiological HDL function in apoE−/− mice [Pubmed: 32726461] |
Int Immunopharmacol | BNIP3 deletion ameliorated enterovirus 71 infection-induced hand, foot and mouth disease via inhibiting apoptosis, autophagy, and inflammation in mice [Pubmed: 32717566] |
Life Sci | Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo study [Pubmed: 32652140] |
Life Sciences | Curcumin and LOXblock-1 ameliorate ischemia-reperfusion induced inflammation and acute kidney injury by suppressing the semaphorin-plexin pathway. [Pubmed: 32603817] |
Molecular Medicine Reports | Aquaporin‑4 deletion ameliorates enterovirus 71 infection in mice [Pubmed: 32582978] |
Life Sci | Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway [Pubmed: 32428599] |
JOURNAL OF IMMUNOLOGY RESEARCH | β-Defensin Strengthens Antimicrobial Peritoneal Mast Cell Response [Pubmed: 32411798] |
cell metabolism | Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis [Pubmed: 32375062] |
Nanoscale Research Letters | Protective Effects of Carbon Dots Derived from Phellodendri Chinensis Cortex Carbonisata against Deinagkistrodon acutus Venom-Induced Acute Kidney … [] |
J Immunoassay Immunochem | Effects of regular exercise on inflammatory biomarkers and lipid parameters in soccer players [33750257] |
FASEB Bioadv | Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high©\fat diet©\fed hyperglycemic rabbits [33977232] |
Hepatology | TNIP3 is a novel activator of Hippo©\YAP signaling protecting against hepatic ischemia/reperfusion injury [34133792] |
Bioactive Materials | Construction of heparin-based hydrogel incorporated with Cu5. 4O ultrasmall nanozymes for wound healing and inflammation inhibition [33778192] |
researchsquare | p62 promotes HIV-1 gp120 V3 loop-mediated microglial inflammation by promoting noncanonical activation of Nrf2 [] |
Transl Vis Sci Technol | Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes [34357381] |
Cell Metabolism | Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species [34536344] |
Stroke | CCL2 (CC Motif Chemokine Ligand 2) Biomarker Responses in Central Versus Peripheral Compartments After Focal Cerebral Ischemia [34587791] |
J Ethnopharmacol | Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and … [34699947] |
Biomed Pharmacother | Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats [Pubmed:35430394] |
Expert Opinion on Therapeutic Targets | Dapagliflozin mitigates ovalbumin-prompted airway inflammatory-oxidative successions and associated bronchospasm in a rat model of allergic asthma [Pubmed:35549595] |
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