淀粉样蛋白β1-42(Ab1-42)合成多肽
Synthetic Amyloid Beta Peptide 1-42 (Ab1-42)
- 编号SPA946Hu02
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源多肽合成
- 预测分子量-
- 缓冲液成份磷酸盐缓冲液(pH7.4,含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.)
- 性状冻干粉
- 纯度> 90%
- 等电点-
-
应用
Immunogen; Blocking Peptide.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 720 ¥ 1800 ¥ 3600 ¥ 10800 ¥ 27000
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
序列
用法
PBS或其它。
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
CPA946Hu12 | 淀粉样蛋白β1-42(Ab1-42)牛血清白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
SPA946Hu02 | 淀粉样蛋白β1-42(Ab1-42)合成多肽 | Immunogen; Blocking Peptide. |
CPA946Hu11 | 淀粉样蛋白β1-42(Ab1-42)牛血清白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
CPA946Hu31 | 淀粉样蛋白β1-42(Ab1-42)钥孔血蓝蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
CPA946Hu22 | 淀粉样蛋白β1-42(Ab1-42)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
CPA946Hu21 | 淀粉样蛋白β1-42(Ab1-42)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
PAA946Hu08 | 淀粉样蛋白β1-42(Ab1-42)多克隆抗体 | WB; IHC; ICC; IP. |
MAA946Hu21 | 淀粉样蛋白β1-42(Ab1-42)单克隆抗体 | WB; IHC; ICC; IP. |
MAA946Hu22 | 淀粉样蛋白β1-42(Ab1-42)单克隆抗体 | WB; IHC; ICC; IP. |
MEA946Hu | 淀粉样蛋白β1-42(Ab1-42)检测试剂盒(酶联免疫吸附试验法,小样本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
CEA946Hu | 淀粉样蛋白β1-42(Ab1-42)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
HEA946Hu | 淀粉样蛋白β1-42(Ab1-42)检测试剂盒(酶联免疫吸附试验法,高敏型) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA946Hu | 淀粉样蛋白β1-42(Ab1-42)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Neuropsychopharmacology | Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease [Pubmed: 23493042] |
Neuropharmacology and analgesia | The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1–42 seeding and short-term memory deficits in the Aβ25–35 mouse model of Alzheimer's disease [Pubmed: 23123349] |
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南方医科大学学报 | 外源性硫化氢对高糖条件下原代神经元β淀粉样蛋白的影响 [J-Smu:Source] |
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Світ медицини та біології | ОСОБЕННОСТИ ПРОЦЕССОВ ФОРМИРОВАНИЯ ПОКАЗАТЕЛЕЙ ФУНКЦИОНАЛЬНОГО СОСТОЯНИЯ ВЫСШЕЙ НЕРВНОЙ ДЕЯТЕЛЬНОСТИ И ХАРАКТЕРИСТИКИ ВНИМАНИЯ СТУДЕНТОВ [SMB-2016-03-062.pdf] |
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Archives of Pharmacal Research | Geniposide attenuates the level of Aβ1–42 via enhancing leptin signaling in cellular and APP/PS1 transgenic mice [pubmed:28160136] |
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Scientific Reports | Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer’s disease [articles:srep41041.ris] |
Journal of Medicinal Food | Cerebrosides from Sea Cucumber Protect Against Oxidative Stress in SAMP8 Mice and PC12 Cells [pubmed:28406733] |
Journal of Nutritional Biochemistry | Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet [Pubmed:29986309] |
Biochemical Pharmacology | Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats [Pubmed:30028991] |
Journal of Affective Disorders | Sub-chronic celecoxib prevents soluble beta amyloid-induced depressive-like behaviour in rats [Pubmed:29879605] |
Biomedicine & Pharmacotherapy | Punicalagin ameliorates the elevation of plasma homocysteine, amyloid-β, TNF-α and apoptosis by advocating antioxidants and modulating apoptotic mediator proteins in brain modulating apoptotic mediator … [Pubmed:29579708] |
Journal of Agricultural and Food Chemistry | Effects of Astaxanthin and Docosahexaenoic-Acid-Acylated Astaxanthin on Alzheimer's Disease in APP/PS1 Double-Transgenic Mice [Pubmed:29695154] |
Neurotoxicology | Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats [Pubmed:29522778] |
Biochemical and Biophysical Research Communications | CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease [Pubmed:29777699] |
Oncotarget | Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse … [Pubmed:29731975] |
Experimental and Therapeutic Medicine | Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β‑amyloid production and tau hyperphosphorylation [Doi: 10.3892/etm.2018.6860] |
非编码RNA miR-137 调控tau 蛋白磷酸化和L 型钙离子通道CACNA1C 参与阿尔茨海默病的发生 [] | |
台湾农业研究 | (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探 [] |
The Efficacy of Sauropus androgynus Leaves Extract To Improve Cognitive Function in Wistar Rats Induced Alzheimer's [] | |
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Neurochemical Research | Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation [Pubmed: 30756214] |
Molecular and Cellular Biochemistry | Repetitive transcranial magnetic stimulation protects mice against 6-OHDA-induced Parkinson's disease symptoms by regulating brain amyloid β level [] |
PLoS One | Obstructive sleep apnea may increase the risk of Alzheimer's disease [Pubmed: 31487291] |
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Pharmacognosy Magazine | Mahanimbine-induced neuroprotection via cholinergic system and attenuated amyloidogenesis as well as neuroinflammation in lipopolysaccharides-induced … [] |
biosciences biotechnology research asia | Dietary Malted Barley Grain Improved Structure and Function of Spinal Cord of Mother Rats fed on a high cholesterol diet. [] |
Neurochem Res | Ex Vivo Investigation of Bexarotene and Nicotinamide Function as a Protect?ve Agent on Rat Synaptosomes Treated with A¦Â (1-42) [33428094] |
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PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | The effect of a 6-month Ketogenic Medium-Chain Triglyceride Supplement on Plasma Cardiometabolic and Inflammatory Markers in Mild Cognitive?¡ [33906081] |
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