淀粉样前体蛋白(APP)重组蛋白
Recombinant Amyloid Precursor Protein (APP)
AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein
- 编号RPB020Mu02
- 物种Mus musculus (Mouse,小鼠) 相同的名称,不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜, 细胞核, 分泌, 细胞质
- 预测分子量7.9kDa
- 实际分子量12kDa(差异分析请参阅说明书)
- 片段与标签Asp672~Val711 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
- 性状冻干粉
- 纯度> 95%
- 等电点4.7
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1152 ¥ 2880 ¥ 5760 ¥ 17280 ¥ 43200
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
编号 | 适用物种:Mus musculus (Mouse,小鼠) | 应用(仅供研究使用,不用于临床诊断!) |
RPB020Mu01 | 淀粉样前体蛋白(APP)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB020Mu02 | 淀粉样前体蛋白(APP)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB020Mu02 | 淀粉样前体蛋白(APP)多克隆抗体 | WB; IHC; ICC; IP. |
PAB020Mu01 | 淀粉样前体蛋白(APP)多克隆抗体 | WB; IHC; ICC; IP. |
LAB020Mu81 | 淀粉样前体蛋白(APP)多克隆抗体(异硫氰酸荧光素标记) | WB; IHC; ICC; IF. |
LAB020Mu71 | 淀粉样前体蛋白(APP)多克隆抗体(生物素标记) | WB; IHC; ICC. |
MEB020Mu | 淀粉样前体蛋白(APP)检测试剂盒(酶联免疫吸附试验法,小样本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SEB020Mu | 淀粉样前体蛋白(APP)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB020Mu | 淀粉样前体蛋白(APP)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Neurochemistry International | Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway [ScienceDirect: S0197018611001641] |
Neuroscience | Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein [Pubmed: 23707801] |
OncoImmunology | PROOF COVER SHEET [] |
台湾农业研究 | (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探 [] |
Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice [Pubmed: 32522471] |
Metab Brain Dis | Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal … [Pubmed:35312928] |
Exp Gerontol | The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and … [Pubmed:35217193] |
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