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β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白

Recombinant Beta-Site APP Cleaving Enzyme 1 (bACE1)

ASP2; Beta Secretase; Memapsin 2; Aspartyl protease 2; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2

  • 编号RPA718Mu01
  • 物种Mus musculus (Mouse，小鼠) 相同的名称，不同的物种。
  • 来源原核表达
  • 宿主E.coli
  • 内毒素水平<1.0EU/µg(LAL法测定)
  • 亚细胞定位Membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum. Endosome. Cell surface. Cytoplasmic vesicle membra
  • 预测分子量59.0kDa
  • 实际分子量57kDa(差异分析请参阅说明书)
  • 片段与标签Pro190~Ala430 (Accession # P56818) with N-terminal His and GST Tag
  • 缓冲液成份磷酸盐缓冲液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
  • 性状冻干粉
  • 纯度> 95%
  • 等电点5.8
  • 应用 Positive Control; Immunogen; SDS-PAGE; WB.
    如果需要有生物活性的蛋白，请参见活性蛋白。
  • 下载 英文说明书   中文说明书
  • 规格 10µg50µg 200µg 1mg 5mg
  • 价格 ¥ 1051 ¥ 2628 ¥ 5256 ¥ 15768 ¥ 39420
  • 欲了解实际交易价格和更多情况，请与当地经销商联系!
  • β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白 产品包装(模拟)
  • β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白 产品包装(模拟)
  • RPA718Mu01.jpg SDS-PAGE图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

序列

用法

PBS或其它。

储存

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

相关产品

编号 适用物种：Mus musculus (Mouse，小鼠) 应用(仅供研究使用，不用于临床诊断！)
RPA718Mu02 β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA718Mu01 β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA718Mu01 β-位淀粉样前体蛋白裂解酶1(bACE1)多克隆抗体 WB; IHC; ICC; IP.
PAA718Mu02 β-位淀粉样前体蛋白裂解酶1(bACE1)多克隆抗体 WB; IHC; ICC; IP.
SEA718Mu β-位淀粉样前体蛋白裂解酶1(bACE1)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA718Mu β-位淀粉样前体蛋白裂解酶1(bACE1)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
Food & Function Comparative study of the effects of phosphatidylcholine rich in DHA and EPA on Alzheimer’s disease and the possible mechanisms in CHO-APP/PS1 cells and SAMP8 mice [pubmed:29292421]
Journal of Functional Foods EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation [10.1016/j.jff.2017.12.016]
Journal of Nutritional Biochemistry Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet [Pubmed:29986309]
Neurotoxicology Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice [Pubmed: 32522471]
Food Chem Toxicol Effects of Alcohol Intake on Cognitive Function and ¦Â-amyloid Protein in APP/PS1 Transgenic Mice [33737111]
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