趋化因子C-X-C-基元受体4(CXCR4)重组蛋白
Recombinant Chemokine C-X-C-Motif Receptor 4 (CXCR4)
CD184; Fusin; NPYR; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYRL; WHIM; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide-associated protein 3
- 编号RPA940Hu01
- 物种Homo sapiens (Human，人) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜, 溶酶体
- 预测分子量13.6kDa
- 实际分子量16kDa(差异分析请参阅说明书)
- 片段与标签Asp262~Ser352 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 90%
- 等电点8.6
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1046 ¥ 2616 ¥ 5232 ¥ 15696 ¥ 39240
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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Figure . Gene Sequencing (extract)
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Figure. SDS-PAGE
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA940Hu01 | 趋化因子C-X-C-基元受体4(CXCR4)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPA940Hu21 | 趋化因子C-X-C-基元受体4(CXCR4)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
| PAA940Hu08 | 趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体 | WB; IHC; ICC; IP. |
| PAA940Hu01 | 趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体 | WB; IHC; ICC; IP. |
| FAA940Hu01 | 抗趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体 | Flow cytometry. |
| FAA940Hu41 | 抗趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体(藻红素标记) | Flow cytometry. |
| FAA940Hu51 | 抗趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体(别藻蓝蛋白标记) | Flow cytometry. |
| FAA940Hu81 | 抗趋化因子C-X-C-基元受体4(CXCR4)多克隆抗体(异硫氰酸荧光素标记) | Flow cytometry. |
| MAA940Hu22 | 趋化因子C-X-C-基元受体4(CXCR4)单克隆抗体 | WB; IHC; ICC; IP. |
| RAA940Hu21 | 趋化因子C-X-C-基元受体4(CXCR4)重组抗体 | WB; IF; ICC; IHC; IP; FCM. |
| SEA940Hu | 趋化因子C-X-C-基元受体4(CXCR4)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA940Hu | 趋化因子C-X-C-基元受体4(CXCR4)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| International Journal of Cancer | Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model [Wiley: source] |
| Plos one | Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma [PubMed: PMC3589458] |
| Atherosclerosis | The non-alcoholic fraction of beer increases stromal cell derived factor 1 and the number of circulating endothelial progenitor cells in high cardiovascular risk subjects: A randomized clinical trial [Pubmed:24530788] |
| Pharmacol Rep.? | Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression [Pubmed:25150002] |
| Pharmacological Reports | Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorder [PubMed: 26481549] |
| Pharmacological Reports | A study of chemokines, chemokine receptors and interleukin-6 in patients with panic disorder, personality disorders and their co-morbidity [Pubmed:27208878] |
| BMC Cancer. | Enhancement of the CXCL12/CXCR4 axis due to acquisition of gemcitabine resistance in pancreatic cancer: effect of CXCR4 antagonists [pmc:PMC4866076] |
| Frontiers in Bioengineering and Biotechnology | Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison … [Pubmed:29670878] |
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