颗粒酶B(GZMB)真核蛋白
Eukaryotic Granzyme B (GZMB)
GZM-B; HLP; CTLA1; CCPI; CGL1; CSP-B; CSPB; CTSGL1; SECT; Granzyme 2; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Fragmentin 2; Cytotoxic Serine Protease B
- 编号EPA600Ra62
- 物种Rattus norvegicus (Rat,大鼠) 相同的名称,不同的物种。
- 来源真核表达
- 宿主293F cell
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌, 溶酶体
- 预测分子量56.4kDa
- 实际分子量65kDa(差异分析请参阅说明书)
- 片段与标签Gly19~Ser248 with N-terminal His Tag and C-terminal Fc Region of Human IgG1
- 缓冲液成份PBS, pH7.4, containing 5% Trehalose.
- 性状冻干粉
- 纯度> 80%
- 等电点10.1
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 暂无报价 暂无报价 暂无报价 暂无报价 暂无报价
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序列
用法
Reconstitute in ddH2O to a concentration less than or equal to 0.1mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
编号 | 适用物种:Rattus norvegicus (Rat,大鼠) | 应用(仅供研究使用,不用于临床诊断!) |
RPA600Ra01 | 颗粒酶B(GZMB)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA600Ra62 | 颗粒酶B(GZMB)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA600Ra01 | 颗粒酶B(GZMB)多克隆抗体 | WB; IHC; ICC; IP. |
MAA600Ra21 | 颗粒酶B(GZMB)单克隆抗体 | WB; IHC; ICC; IP. |
SEA600Ra | 颗粒酶B(GZMB)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA600Ra | 颗粒酶B(GZMB)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
International Journal of Cancer | Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70 [Pubmed:24691976] |
Biol Pharm Bull. | Z-100, an Immunomodulatory Extract of Mycobacterium tuberculosis Strain Aoyama B, Prevents Spontaneous Lymphatic Metastasis of B16-BL6 Melanoma [Pubmed:24818259] |
Journal of Dermatological Science | Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopicdermatitis. [pubmed:27686401] |
Oncotarget | Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment [Pubmed:29983866] |
Theranostics | A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors [Pubmed: 31695790] |
Am J Transl Res | Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma [34377237] |
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