神经调节素1(NRG1)重组蛋白
Recombinant Neuregulin 1 (NRG1)
ARIA; GGF; HGL; HRG; HRGA; NDF; SMDF; Acetylcholine receptor-inducing activity; Glial growth factor; Heregulin; Neu differentiation factor; Sensory and motor neuron-derived factor
- 编号RPB866Ra01
- 物种Rattus norvegicus (Rat，大鼠) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜, 分泌
- 预测分子量15.7kDa
- 实际分子量20/18kDa(差异分析请参阅说明书)
- 片段与标签Thr264~Gly393 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 95%
- 等电点9.3
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 864 ¥ 2160 ¥ 4320 ¥ 12960 ¥ 32400
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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Figure . Gene Sequencing (extract)
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SDS-PAGE图
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPB866Ra01 | 神经调节素1(NRG1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra02 | 神经调节素1(NRG1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra03 | 神经调节素1(NRG1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra04 | 神经调节素1(NRG1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB866Ra02 | 神经调节素1(NRG1)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB866Ra03 | 神经调节素1(NRG1)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB866Ra01 | 神经调节素1(NRG1)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB866Ra04 | 神经调节素1(NRG1)多克隆抗体 | WB; IHC; ICC; IP. |
| LAB866Ra71 | 神经调节素1(NRG1)多克隆抗体(生物素标记) | WB; IHC; ICC. |
| SEB866Ra | 神经调节素1(NRG1)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| WEB866Ra | 神经调节素1(NRG1)检测试剂盒(酶联免疫吸附试验法,宽范围) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB866Ra | 神经调节素1(NRG1)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Neuroscience Letter | Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom [Cyagen: source] |
| PLoS One. | ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis [PubMed: PMC3519469] |
| The Journal of Clinical Investigation | Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration [PubMed: PMC3428100] |
| Physiol Behav | Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress [PubMed: 26626816] |
| J Toxicol Sci. | Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. [Pubmed:26961615] |
| journal of cellular and molecular medicine | Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. [pubmed:28271613] |
| Transl Psychiatry. | Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. [pubmed:28267150] |
| Human Molecular Genetics | A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas [Pubmed: 30335132] |
| Aging (Albany NY) | Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin [Pubmed: 32920546] |
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