骨膜蛋白(POSTN)重组蛋白
Recombinant Periostin (POSTN)
OSF-2; PDLPOSTN; PN; Osteoblast Specific Factor 2
- 编号RPH339Ra02
- 物种Rattus norvegicus (Rat,大鼠) 相同的名称,不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量18.5kDa
- 实际分子量18kDa(差异分析请参阅说明书)
- 片段与标签Arg659~Gln810 with N-terminal His Tag
- 缓冲液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性状冻干粉
- 纯度> 95%
- 等电点9.5
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 864 ¥ 2160 ¥ 4320 ¥ 12960 ¥ 32400
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-0.25 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
编号 | 适用物种:Rattus norvegicus (Rat,大鼠) | 应用(仅供研究使用,不用于临床诊断!) |
RPH339Ra01 | 骨膜蛋白(POSTN)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPH339Ra02 | 骨膜蛋白(POSTN)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAH339Ra01 | 骨膜蛋白(POSTN)多克隆抗体 | WB; IHC; ICC; IP. |
PAH339Ra02 | 骨膜蛋白(POSTN)多克隆抗体 | WB; IHC; ICC; IP. |
LAH339Ra71 | 骨膜蛋白(POSTN)多克隆抗体(生物素标记) | WB; IHC; ICC. |
SEH339Ra | 骨膜蛋白(POSTN)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMH339Ra | 骨膜蛋白(POSTN)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Blood | Circulating Periostin Is Elevated In Patients With Hemoglobinopathies and Correlates With Bone Mineral Density In Double Heterozygous Sickle-Cell/Beta-Thalassemia Patients; A Novel Marker Of Bone Strength? [Bloodjournal: Source] |
The Journal of Clinical Endocrinology & Metabolism | Serum periostin is associated with fracture risk in postmenopausal women: a 7 years prospective analysis of the OFELY study [Pubmed: 24628551] |
J Clin Endocrinol Metab. | Serum Periostin Is Associated With Fracture Risk in Postmenopausal Women: A 7-Year Prospective Analysis of the OFELY Study [Pubmed:24628551] |
Rheumatology (Oxford). | Circulating periostin levels in patients with AS: association with clinical and radiographic variables, inflammatory markers and molecules involved in bone formation [Pubmed:25349442] |
Journal of Periodontal Research | Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease [Pubmed:25529858] |
新医学 | 血清内脂素水平与多囊卵巢综合征的相关性研究 [Xinyixue:Source] |
Osteoarthritis | Serum periostin is associated with prevalent knee osteoarthritis and disease incidence/progression in women: the OFELY study [PubMed: 26072384] |
Endocrine | Serum periostin is a potential biomarker for non-alcoholic fatty liver disease: a case– control study [PubMed: 26362060] |
Blood Cancer Journal | High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly … [pubmed:27716740] |
Metabolism. | Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity. [pubmed:28521873] |
Osteoporosis International | Circulating periostin levels increase in association with bone density loss and healing progression during the early phase of hip fracture in Chinese older women [pubmed:28382553] |
Molecular Diagnosis & Therapy | The Utility of Biomarkers in Osteoporosis Management [pubmed:28271451] |
Journal of Bone and Mineral Research | Cortical and trabecular bone microstructure did not recover at weight-bearing skeletal sites and progressively deteriorated at non-weight-bearing sites during the year following International Space Station missions [doi:10.1002] |
Clinical Cases in Mineral and Bone Metabolism | Periostin and sclerostin levels in juvenile Paget's disease [pubmed:29263750] |
Calcified Tissue International | Development of a New Immunoassay for Human Cathepsin K-Generated Periostin Fragments as a Serum Biomarker for Cortical Bone [pubmed:28725907] |
Wiley | Characterization of a sandwich ELISA for the quantification of all human periostin isoforms [pubmed:28493527] |
International Osteoporosis Foundation and National Osteoporosis Foundation | Interaction between LRP5 and periostin gene polymorphisms on serum periostin levels and cortical bone microstructure [pubmed:29038835] |
Bone | Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones [pubmed:28323143] |
Clinica Chimica Acta | Association between serum periostin concentrations and outcome after acute spontaneous intracerebral hemorrhage [pubmed:28882488] |
Clinica Chimica Acta | Serum periostin concentrations and outcomes after severe traumatic brain injury [pubmed:28668564] |
Tumor Biology | Predictive and prognostic value of serum periostin in advanced non–small cell lung cancer patients receiving chemotherapy [pubmed:28459197] |
Journal of Bone and Mineral Research | Serum Levels of a Cathepsin-K Generated Periostin Fragment Predict Incident Low-Trauma Fractures in Postmenopausal Women Independently of BMD and FRAX [pubmed:28766739] |
ОСОБЕННОСТИ СОСТОЯНИЯ ЗДОРОВЬЯ НОВОРОЖДЕННЫХ, РОЖДЕННЫХ ОТ МАТЕРЕЙ С БРОНХИАЛЬНОЙ АСТМОЙ [2017; 62:(4)] | |
Endocrine | Circulating periostin in patients with nonalcoholic fatty liver disease. [pubmed:27738886] |
Molecular Medicine Reports | Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development [pubmed:28849131] |
The Journal of Biological Chemistry | Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice [Pubmed:29929978] |
Calcified Tissue International | The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis [Pubmed:29916127] |
Journal of Endocrinological Investigation | Increased serum periostin concentrations are associated with the presence of diabetic retinopathy in patients with type 2 diabetes mellitus [Pubmed:29349642] |
Wiener klinische Wochenschrift | Rheumatoid arthritis in remission [] |
Clinical and Experimental Medicine | Myostatin and other musculoskeletal markers in lung transplant recipients [Pubmed: 30317402] |
Experimental and Clinical Endocrinology & Diabetes | Polycystic Ovary Syndrome is Associated with Elevated Periostin Levels [Pubmed: 30372763] |
ИСПОЛЬЗОВАНИЕ СЫВОРОТОЧНОГО ПЕРИОСТИНА В КАЧЕСТВЕ МАРКЕРА ОБОСТРЕНИЙ АСТМЫ У ДЕТЕЙ [] | |
Bone | Tartrate-resistant acid phosphatase 5b, but not periostin, is useful for assessing Paget's disease of bone [Pubmed: 31051316] |
Journal of Clinical Laboratory Analysis | Identification and diagnostic value of pleural fluid periostin and serum periostin of malignant pleural effusions in patients with non–small‐cell lung cancer [Pubmed: 31268191] |
Bone | Serum periostin is associated with cancer mortality but not cancer risk in older home-dwelling men: A 8-year prospective analysis of the STRAMBO study [Pubmed: 31812700] |
FASEB J | Fibronectin rescues aberrant phenotype of endothelial cells lacking either CCM1, CCM2 or CCM3 [Pubmed: 32515053] |
Journal of Reproductive Immunology | Serum and placental periostin levels in women with early pregnancy loss [Pubmed: 32460058] |
Annals of Medical Research | Evaluation of periostin levels in gingival crevicular fluid and peri-implant sulcus fluid in patients with periodontal and peri-implanter disease: A cross-sectional … [] |
Myostatin and Markers of Bone Metabolism in Dermatomyositis [] | |
Am J Physiol Heart Circ Physiol | Periostin promotes arterial calcification through PPAR¦Ã-related glucose metabolism reprogramming [33834866] |
International Journal of Chronic Obstructive Pulmonary Disease | High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease [33814903] |
J Bone Oncol | Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma [34150488] |
Rambam Maimonides Med J | The Relationship between Serum Periostin Levels and Neutrophil¨CLymphocyte Ratio with Lesion Localization and Acute Prognosis in Acute Ischemic Stroke [34137680] |
Rambam Maimonides Medical Journal | First Admission Neutrophil–Lymphocyte Ratio May Indicate Acute Prognosis of Ischemic Stroke [34137680] |
留言咨询