过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARgC1a)重组蛋白
Recombinant Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a)
LEM6; PGC-1(alpha); PGC-1v; PGC1; PGC1A; PPARGC1; Ligand effect modulator 6
- 编号RPH337Mu01
- 物种Mus musculus (Mouse，小鼠) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞核
- 预测分子量24.7kDa
- 实际分子量24kDa(差异分析请参阅说明书)
- 片段与标签Cys577~Asn766 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 97%
- 等电点9.4
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1099 ¥ 2748 ¥ 5496 ¥ 16488 ¥ 41220
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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SDS-PAGE图
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Mus musculus (Mouse，小鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPH337Mu02 | 过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARgC1a)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPH337Mu01 | 过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARgC1a)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAH337Mu01 | 过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARgC1a)多克隆抗体 | WB; IHC; ICC; IP. |
| PAH337Mu02 | 过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARgC1a)多克隆抗体 | WB; IHC; ICC; IP. |
| SEH337Mu | 过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARgC1a)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMH337Mu | 过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARgC1a)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Coronary Artery Disease | Impaired myocardium energetics associated with the risk for new-onset atrial fibrillation after isolated coronary artery bypass graft surgery [Pubmed: 24463787] |
| Molecular and cellular biochemistry | Skeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension [Pubmed: 23099843] |
| Diabetes. | Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway [Pubmed:25249574] |
| Psychoneuroendocrinology | Maternal stress predicts altered biogenesis and the profile of mitochondrial proteins in the frontal cortex and hippocampus of adult offspring rats [PubMed: 26143539] |
| Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry | The level of circulating PGC1α in cardiovascular diseases [Article: 10.1134] |
| Neuroscience Letters | Unlike PPARgamma, neither other PPARs nor PGC-1alpha is elevated in the cerebrospinal fluid of patients with multiple sclerosis [pubmed:28483651] |
| The American Journal of the Medical Sciences | Serum peroxisome proliferator-activated receptor gamma coactivator-1α related to myocardial energy expenditure in patients with chronic heart failure [Doi: 10.1016/j.amjms.2018.12.002] |
| Brain Research | The effect of antecedent-conditioning high-intensity interval training on BDNF regulation through PGC-1α pathway following cerebral ischemia [Pubmed: 31866362] |
| Food & Function | Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise [Pubmed: 32797125] |
| Brown and beige adipose tissue regulate systemic metabolism to resist diet-induced obesity through metabolite signals in an inter-organ signaling axis [] | |
| CLINICAL NUTRITION | Long lasting protective EFFECTS of early L-ARGININE TREAMENT on ENDOTHELIUM in an in Vitro STUDY [33743287] |
| Nature Communications | Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis [33772024] |
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