色素上皮衍生因子(PEDF)重组蛋白
Recombinant Pigment Epithelium Derived Factor (PEDF)
SERPINF1; EPC1; PIG35; SDF3; Serpin F1; Cell proliferation-inducing gene 35; Serpin Peptidase Inhibitor,Clade F Member 1(Alpha-2 Antiplasmin); Stromal Cell Derived Factor 3
- 编号RPB972Mu03
- 物种Mus musculus (Mouse，小鼠) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量18.7kDa
- 实际分子量19kDa(差异分析请参阅说明书)
- 片段与标签Ile262~Thr417 (Accession # P97298) with N-terminal His Tag
- 缓冲液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性状冻干粉
- 纯度> 97%
- 等电点5.65
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1152 ¥ 2880 ¥ 5760 ¥ 17280 ¥ 43200
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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SDS-PAGE图
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Mus musculus (Mouse，小鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPB972Mu01 | 色素上皮衍生因子(PEDF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB972Mu02 | 色素上皮衍生因子(PEDF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB972Mu03 | 色素上皮衍生因子(PEDF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB972Mu01 | 色素上皮衍生因子(PEDF)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB972Mu03 | 色素上皮衍生因子(PEDF)多克隆抗体 | WB; IHC; ICC; IP. |
| PAB972Mu02 | 色素上皮衍生因子(PEDF)多克隆抗体 | WB; IHC; ICC; IP. |
| LAB972Mu81 | 色素上皮衍生因子(PEDF)多克隆抗体(异硫氰酸荧光素标记) | WB; IHC; ICC; IF. |
| LAB972Mu71 | 色素上皮衍生因子(PEDF)多克隆抗体(生物素标记) | WB; IHC; ICC. |
| MAB972Mu21 | 色素上皮衍生因子(PEDF)单克隆抗体 | WB,IHC |
| MAB972Mu22 | 色素上皮衍生因子(PEDF)单克隆抗体 | WB; IHC; ICC; IP. |
| MEB972Mu | 色素上皮衍生因子(PEDF)检测试剂盒(酶联免疫吸附试验法,小样本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEB972Mu | 色素上皮衍生因子(PEDF)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB972Mu | 色素上皮衍生因子(PEDF)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMB972Mu | 色素上皮衍生因子(PEDF)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
| KSB972Mu01 | 色素上皮衍生因子(PEDF)检测试剂盒DIY材料(酶联免疫吸附试验法) | Main materials for "Do It (ELISA Kit) Yourself". |
参考文献
| 杂志 | 参考文献 |
| Molecular Therapy | A Therapeutic Strategy for Choroidal Neovascularization Based on Recruitment of Mesenchymal Stem Cells to the Sites of Lesions [Nature: 2010144] |
| American Journal of Nephrology | Urinary Pigment Epithelium-Derived Factor as a Marker of Diabetic Nephropathy [Karger: 314326] |
| 34 | Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury [OxfordJournals: source] |
| Heart and Education in Heart | The change of serum level of pigment epithelium-derived factor in coronary heart disease [Bmj: Source] |
| Mediators of Inflammation | Metformin Inhibits Expression and Secretion of PEDF in Adipocyte and Hepatocyte via Promoting AMPK Phosphorylation [Pubmed: 24288442] |
| Cardiology. | The association study of plasma levels of pigment epithelium-derived factor with acute coronary syndrome in the chinese han population. [Pubmed: 24192856] |
| Endocrinology | Rosiglitazone Inhibits Expression and Secretion of PEDF in Adipose Tissue and Liver of Male SD Rats Via a PPAR-γ Independent Mechanism [Endocrine: Source] |
| Clinical Science | Pigment epithelium-derived factor regulates microvascular permeability through adipose triglyceride lipase in sepsis [PubMed: 25700221] |
| Molecular Sciences | Pigment Epithelium-Derived Factor (PEDF) Protects Osteoblastic Cell Line from Glucocorticoid-Induced Apoptosis via PEDF-R [Pubmed:27187377] |
| Investigative ophthalmoloey & visual science | The Ingenious Interactions Between Macrophages and Functionally Plastic Retinal Pigment Epithelium Cells [articleid:2582822] |
| Scientific reports | VEGF-B promotes recovery of corneal innervations and trophic functions in diabetic mice [pubmed:28091556] |
| 国际眼科杂志 | 色素上皮衍生因子修饰的人脐带间充质干细胞构建方法 [201707007] |
| Investigative Ophthalmology & Visual Science | PEDF Reduces the Severity of Herpetic Simplex Keratitis in Mice [Pubmed:30025136] |
| International Eye Science | 高海拔地区新生血管性青光眼不同治疗方式的疗效及对房水中PEDF, VEGF 水平的影响 [2018/2/201802020.pdf] |
| Domestic Animal Endocrinology | Lactation-related changes in tissue expression of PEDF in dairy cows [Pubmed:29758402] |
| Medical Science Monitor | Correlation Between Pigment Epithelium-Derived Factor (PEDF) level and Degree of Coronary Angiography and Severity of Coronary Artery Disease in a … [Pubmed:29574467] |
| Chemosphere | Role of pigment epithelium-derived factor (PEDF) on arsenic-induced neuronal apoptosis [Doi: 10.1016/j.chemosphere.2018.10.100] |
| Biological Trace Element Research | Role of Pigment Epithelium-Derived Factor in Arsenic-Induced Vascular Endothelial Dysfunction in a Rat Model [Pubmed: 30392020] |
| International Urology and Nephrology | Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement [Pubmed: 30536192] |
| International Journal of Ophthalmology | A novel xeno-free culture system for human retinal pigment epithelium cells [Pubmed: 31024807] |
| Journal of the American Heart Association | Pigment Epithelial‐Derived Factor Deficiency Accelerates Atherosclerosis Development via Promoting Endothelial Fatty Acid Uptake in Mice With Hyperlipidemia [Pubmed: 31711388] |
| environmental research | Pigment epithelium-derived factor (PEDF) ameliorates arsenic-induced vascular endothelial dysfunction in rats and toxicity in endothelial EA. hy926 cells [Pubmed: 32315827] |
| INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | The Expression Levels and Cellular Localization of Pigment Epithelium Derived Factor (PEDF) in Mouse Testis: Its Possible Involvement in the Differentiation of Spermatogonial Cells [33498962] |
| Hum Cell | Long non-coding RNA Rian promotes the expression of tight junction proteins in endothelial cells by regulating perivascular-resident macrophage-like melanocytes ¡ [33768511] |
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