尿激酶型纤溶酶原激活因子(uPA)重组蛋白
Recombinant Plasminogen Activator, Urokinase (uPA)
PLAU; ATF; URK; UK; UP-A; Abbokinase; Urokinase-Type Plasminogen Activator
- 编号RPA140Hu01
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量50.1kDa
- 实际分子量50kDa(差异分析请参阅说明书)
- 片段与标签Ser21~Leu431 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300)
- 性状冻干粉
- 纯度> 80%
- 等电点5.0
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
RPA140Hu01 | 尿激酶型纤溶酶原激活因子(uPA)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APA140Hu61 | 尿激酶型纤溶酶原激活因子(uPA)活性蛋白 | Cell culture; Activity Assays. |
EPA140Hu61 | 尿激酶型纤溶酶原激活因子(uPA)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA140Hu01 | 尿激酶型纤溶酶原激活因子(uPA)多克隆抗体 | WB; IHC; ICC; IP. |
MAA140Hu22 | 尿激酶型纤溶酶原激活因子(uPA)单克隆抗体 | WB; IHC; ICC; IP. |
SEA140Hu | 尿激酶型纤溶酶原激活因子(uPA)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA140Hu | 尿激酶型纤溶酶原激活因子(uPA)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
LMA140Hu | 尿激酶型纤溶酶原激活因子(uPA)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Breast Cancer Research and Treatment | Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice [SpringerLink: f3w831267267p277] |
Biomarker insights | Decreased Hepatocyte Growth Factor (HGF) and Gamma Aminobutyric Acid (GABA) in Individuals with Obsessive-Compulsive Disorder (OCD) [PubMed: PMC3762604] |
Oncol Rep. | Downregulation of MACC1 inhibits invasion, migration and proliferation, attenuates cisplatin resistance and induces apoptosis in tongue squamous cell carcinoma [Pubmed:25421538] |
International Journal of Oncology | 1, 25-Dihydroxyvitamin D3 alleviates salivary adenoid cystic carcinoma progression by suppressing GPX1 expression through the NF-κB pathway [Pubmed:26782341] |
Biochemical and Biophysical Research Communications | Methylation of neurofilament light polypeptide promoter is associated with cell invasion and metastasis in NSCLC [Pubmed:26801564] |
39 | Cytokine and Estrogen Stimulation of Endothelial Cells Augments Activation of the Surface-Bound Prekallikrein-High Molecular Weight Kininogen Complex: Implications for Hereditary Angioedema (HAE): 814 [article:S0091-6749(15)02643-3] |
SCIENCE & TECHNOLOGY | A Study Protocol: Spinal Morphology, Physical Performance, Quality of Life and Biochemical Markers in Adults at Risk of Osteoporotic Fractures [59f7c85aaca272607e2d8d7a] |
Oncotarget | Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma [pubmed:28404945] |
Journal of allergy and clinical immunology | Cytokine and estrogen stimulation of endothelial cells augments activation of the prekallikrein-high molecular weight kininogen complex: Implications for hereditary angioedema. [pubmed:27826093] |
Molecular Medicine Reports | Effect of a synthetic inhibitor of urokinase plasminogen activator on the migration and invasion of human cervical cancer cells in vitro [Pubmed:29328476] |
Phytomedicine | Multi-omics analysis reveals the mechanisms of action and therapeutic regimens of traditional Chinese medicine, Bufei Jianpi granules: Implication for COPD drug … [Pubmed:35121390] |
Cellular and Molecular Life Sciences | IL4 stimulated macrophages promote axon regeneration after peripheral nerve injury by secreting uPA to stimulate uPAR upregulated in injured axons [Pubmed:35536429] |
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