激活蛋白C(APC)重组蛋白
Recombinant Activated Protein C (APC)
- 编号RPA738Ra01
- 物种Rattus norvegicus (Rat，大鼠) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜, 线粒体, 细胞质
- 预测分子量-
- 实际分子量-(差异分析请参阅说明书)
- 片段与标签N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 90%
- 等电点-
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1056 ¥ 2640 ¥ 5280 ¥ 15840 ¥ 39600
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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Figure . Gene Sequencing (extract)
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Figure. SDS-PAGE
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
PBS或其它。
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA738Ra01 | 激活蛋白C(APC)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA738Ra01 | 激活蛋白C(APC)多克隆抗体 | WB; IHC; ICC; IP. |
| SEA738Ra | 激活蛋白C(APC)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA738Ra | 激活蛋白C(APC)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| The Journal of Immunology | Activated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice [Jimmunol: 3413] |
| Critical Care | Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study [BioMed: cc10553] |
| Molecular Endocrinology | Intraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period [Endo: source] |
| Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study [Sjtrem:1757-7241] |
| Crit Care. | Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation [Pubmed:25260379] |
| Am J Physiol Heart Circ Physiol. | Monocytes regulate systemic coagulation and inflammation in abdominal sepsis [Pubmed:25502108] |
| Neuroscience | Protective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model [PubMed: 25936678] |
| Journal of Intensive Care | Activated protein C does not increase in the early phase of trauma with disseminated intravascular coaCavia (Guinea pig )lation: comparison with acute coaCavia (Guinea pig )lopathy of trauma-shock [Pubmed:26734467] |
| Journal of Biological Chemistry | Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells. [JBC:Source] |
| J Thromb Haemost | A multicenter prospective validation study on disseminated intravascular coagulation in trauma‐induced coagulopathy [Pubmed: 32480432] |
| Validation of the Relationship Between Coagulopathy and Localization of Hydroxyethyl Starch on the Vascular Endothelium in a Rat Hemodilution Model [34021192] |
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