Jagged 1蛋白(JAG1)重组蛋白
Recombinant Jagged 1 (JAG1)
CD339; AGS; AHD; AWS; HJ1; JAGL1; Alagille Syndrome; Jagged 1 Protein
- 编号RPB807Ra01
- 物种Rattus norvegicus (Rat，大鼠) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜
- 预测分子量31.9kDa
- 实际分子量32kDa(差异分析请参阅说明书)
- 片段与标签Ser826~Cys1084 with N-terminal His Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 97%
- 等电点6.1
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 996 ¥ 2490 ¥ 4980 ¥ 14940 ¥ 37350
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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Figure. SDS-PAGE
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPB807Ra01 | Jagged 1蛋白(JAG1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
参考文献
| 杂志 | 参考文献 |
| 13 | Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves [PubMed: PMC3506187] |
| Eur J Obstet Gynecol Reprod Biol. | Profiling of selected angiogenesis-related genes in proliferative eutopic endometrium of women with endometriosis [Pubmed: 24188612] |
| PLoS One. | Augmented Osteogenic Responses in Human Aortic Valve Cells Exposed to oxLDL and TLR4 Agonist: A Mechanistic Role of Notch1 and NF-κB Interaction [Pubmed:Pmc4014478] |
| Biochim Biophys Acta.? | Ligation of ICAM-1 on human aortic valve interstitial cells induces the osteogenic response: A critical role of the Notch1-NF-κB pathway in BMP-2 expression [Pubmed:25101972] |
| international journal of oral-medical sciences | Jagged1 Stimulates Bone Resorption during Orthodontic Tooth Movement [Dn: Jlc] |
| Oncology letters | MicroRNA‑26b acts as an antioncogene and prognostic factor in cervical cancer [] |
| Journal of Biological Chemistry | Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy [Pubmed: 31511328] |
| Cell Death & Disease | Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria [33795655] |
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