前蛋白转化酶枯草溶菌素9(PCSK9)重组蛋白
Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
FH3; HCHOLA3; NARC1; Hypercholesterolemia,Autosomal Dominant 3; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9
- 编号RPE189Ra01
- 物种Rattus norvegicus (Rat，大鼠) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌, 溶酶体, 细胞质, 高尔基体, 内质网腔, 内体
- 预测分子量58.1kDa
- 实际分子量58kDa(差异分析请参阅说明书)
- 片段与标签Trp164~Phe428 with N-terminal His and GST Tag
- 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性状冻干粉
- 纯度> 90%
- 等电点5.9
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1195 ¥ 2988 ¥ 5976 ¥ 17928 ¥ 44820
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
-
产品包装(模拟)
-
产品包装(模拟)
-
Figure . Gene Sequencing (extract)
-
SDS-PAGE图
-
通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPE189Ra01 | 前蛋白转化酶枯草溶菌素9(PCSK9)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAE189Ra01 | 前蛋白转化酶枯草溶菌素9(PCSK9)多克隆抗体 | WB; IHC; ICC; IP. |
| MAE189Ra23 | 前蛋白转化酶枯草溶菌素9(PCSK9)单克隆抗体 | WB; IHC; ICC; IP. |
| MAE189Ra22 | 前蛋白转化酶枯草溶菌素9(PCSK9)单克隆抗体 | WB; IHC; ICC; IP. |
| MAE189Ra21 | 前蛋白转化酶枯草溶菌素9(PCSK9)单克隆抗体 | WB; IHC |
| SEE189Ra | 前蛋白转化酶枯草溶菌素9(PCSK9)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LME189Ra | 前蛋白转化酶枯草溶菌素9(PCSK9)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Biological Trace Element Research | Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers [pubmed:28409410] |
| BASIC RESEARCH IN CARDIOLOGY | Autocrine effects of PCSK9 on cardiomyocytes [Pubmed: 33169229] |
| J Transl Med | Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans [33407555] |
| Metabolism | MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice [33775647] |
| Eur Rev Med Pharmacol Sci | Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders [34533801] |
| Clin Exp Hypertens | Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease [Pubmed:35502687] |
留言咨询