拓扑异构酶Ⅱ(TOP2)重组蛋白
Recombinant Topoisomerase II (TOP2)
DNA topoisomerase 2-alpha; DNA topoisomerase II, alpha isozyme
- 编号RPA792Ra01
- 物种Rattus norvegicus (Rat，大鼠) 相同的名称，不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞核
- 预测分子量32.1kDa
- 实际分子量40kDa(差异分析请参阅说明书)
- 片段与标签Gly1079~Ser1328 with N-terminal His Tag
- 缓冲液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性状冻干粉
- 纯度> 97%
- 等电点6.1
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1104 ¥ 2760 ¥ 5520 ¥ 16560 ¥ 41400
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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Figure. Gene Sequencing (Extract)
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Figure. SDS-PAGE
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA792Ra01 | 拓扑异构酶Ⅱ(TOP2)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA792Ra01 | 拓扑异构酶Ⅱ(TOP2)多克隆抗体 | WB; IHC; ICC; IP. |
| MAA792Ra21 | 拓扑异构酶Ⅱ(TOP2)单克隆抗体 | WB; IHC; ICC; IP. |
| SEA792Ra | 拓扑异构酶Ⅱ(TOP2)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA792Ra | 拓扑异构酶Ⅱ(TOP2)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Journal of Experimental & Clinical Cancer Research | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II [pubmed:27852319] |
| Bioorganic & Medicinal Chemistry | Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition. [pubmed:28094224] |
| European Journal of Medicinal Chemistry | Antiproliferative activity of diarylnaphthylpyrrolidine derivative via dual target inhibition [Pubmed: 31884407] |
| Int J Mol Sci | 2-{5-[(Z,2Z)-2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-oxo-2-thioxothiazolidin-3-yl}-3-methylbutanoic Acid as a Potential Anti-Breast Cancer Molecule [Pubmed:35456915] |
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