α-黑素细胞刺激素(aMSH)合成多肽
Synthetic Alpha-Melanocyte Stimulating Hormone (aMSH)
α-MSH; Intermedins; Alpha-Melanotropin, Alpha-Melanocortin; Alpha-Intermedin
- 编号SPA239Mi01
- 物种Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Oryctolagus cuniculus (Rabbit，兔), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Ovis aries; Ovine (Sheep，绵羊) 相同的名称，不同的物种。
- 来源多肽合成
- 预测分子量-
- 缓冲液成份磷酸盐缓冲液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性状冻干粉
- 纯度> 90%
- 等电点-
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应用
Immunogen; Blocking Peptide.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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Figure. MASS Spectrometry of the Original Peptide
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Figure. HPLC of the Original Peptide
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Oryctolagus cuniculus (Rabbit，兔), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Ovis aries; Ovine (Sheep，绵羊) | 应用(仅供研究使用，不用于临床诊断！) |
| CPA239Mi21 | α-黑素细胞刺激素(aMSH)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
| SPA239Mi01 | α-黑素细胞刺激素(aMSH)合成多肽 | Immunogen; Blocking Peptide. |
| PAA239Mi08 | α-黑素细胞刺激素(aMSH)多克隆抗体 | WB; IHC; ICC; IP. |
| MAA239Mi21 | α-黑素细胞刺激素(aMSH)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA239Mi22 | α-黑素细胞刺激素(aMSH)单克隆抗体 | WB; IHC; ICC; IP. |
参考文献
| 杂志 | 参考文献 |
| J Biochem. | Generation of a human bone marrow-derived mesenchymal stem cell line expressing and secreting high levels of bioactive α-melanocyte-stimulating hormone. [Pubmed: 23341471] |
| Pigment Cell Melanoma Res | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit regulated by light [PubMed: 26582755] |
| The Journal of Biological Chemistry | Intermedin Restores Hyperhomocysteinemia-induced Macrophage Polarization and Improves Insulin Resistance in Mice [Pubmed:27080257] |
| Pigment Cell & Melanoma Research | Pharmacological induction of skin pigmentation unveils the neuroendocrine circuit reCavia (Guinea pig )lated by light [Pubmed:26582755] |
| Nature Communications | Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives. [pubmed:28794470] |
| Cell Stem Cell | Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses [Pubmed:29681516] |
| European Neuropsychopharmacology | Epigenetic alterations of the POMC promoter in tobacco dependence [Pubmed:29871818] |
| Neuropeptides | Mechanisms of sustained long-term weight loss after RYGB: α-MSH is a key factor [Pubmed:29685637] |
| Neuropsychobiology | Alcohol Withdrawal and Proopiomelanocortin Neuropeptides in an Animal Model of Alcohol Dependence [Pubmed: 31117084] |
| INTERNATIONAL IMMUNOPHARMACOLOGY | Intermedin alleviates the inflammatory response and stabilizes the endothelial barrier in LPS-induced ARDS through the PI3K/Akt/eNOS signaling pathway [Pubmed: 32892076] |
| J Endocrinol Invest | Serum alpha-melanocyte-stimulating hormone (a-MSH), brain-derived neurotrophic factor (BDNF), and agouti-related protein (AGRP) levels in children with Prader … [Pubmed:35098494] |
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