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脂多糖结合蛋白(LBP)活性蛋白

Active Lipopolysaccharide Binding Protein (LBP)

LPS-Binding Protein

  • 脂多糖结合蛋白(LBP)活性蛋白 产品包装(模拟)
  • 脂多糖结合蛋白(LBP)活性蛋白 产品包装(模拟)
  • APB406Mu02.jpg Figure. SDS-PAGE
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

活性实验

Lipopolysaccharide Binding Protein (LBP) is a soluble acute-phase protein that binds to bacterial lipopolysaccharide (or LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4.This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). It has been reported that LBP can enhance LPS-stimulated IL-8 secretion by THP-1 cells. To test the bioactivity of LBP, THP-1 cells were seeded into 24-well plate at a density of 1x106 cells/mL including 1ug/mL LPS, and treated with certain concentrations (0.625ug/mL-20ug/mL) of LBP for 24h and IL-8 levels in the cell supernatant were determined by ELISA. IL-8 levels in the cell supernatant of THP-1 cells increased significantly after stimulated with LBP have shown in Figure1.

用法

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

相关产品

编号 适用物种:Mus musculus (Mouse,小鼠) 应用(仅供研究使用,不用于临床诊断!)
APB406Mu01 脂多糖结合蛋白(LBP)活性蛋白 Cell culture; Activity Assays.
RPB406Mu02 脂多糖结合蛋白(LBP)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPB406Mu01 脂多糖结合蛋白(LBP)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
APB406Mu02 脂多糖结合蛋白(LBP)活性蛋白 Cell culture; Activity Assays.
PAB406Mu01 脂多糖结合蛋白(LBP)多克隆抗体 WB; IHC; ICC; IP.
PAB406Mu02 脂多糖结合蛋白(LBP)多克隆抗体 WB; IHC; ICC; IP.
SEB406Mu 脂多糖结合蛋白(LBP)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB406Mu 脂多糖结合蛋白(LBP)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

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