粘蛋白5B(MUC5B)重组蛋白
Recombinant Mucin 5 Subtype B (MUC5B)
MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin
- 编号RPA684Hu02
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源原核表达
- 宿主E.coli
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位分泌
- 预测分子量15.7kDa
- 实际分子量16kDa(差异分析请参阅说明书)
- 片段与标签Cys5653~Val5762 with N-terminal His Tag
- 缓冲液成份100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.
- 性状冻干粉
- 纯度> 90%
- 等电点5.1
-
应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 840 ¥ 2100 ¥ 4200 ¥ 12600 ¥ 31500
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
RPA684Hu02 | 粘蛋白5B(MUC5B)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA684Hu01 | 粘蛋白5B(MUC5B)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
CPA684Hu21 | 粘蛋白5B(MUC5B)卵白蛋白偶联物 | Immunogen; SDS-PAGE; WB. |
PAA684Hu01 | 粘蛋白5B(MUC5B)多克隆抗体 | WB; IHC; ICC; IP. |
PAA684Hu02 | 粘蛋白5B(MUC5B)多克隆抗体 | WB; IHC; ICC; IP. |
LAA684Hu81 | 粘蛋白5B(MUC5B)多克隆抗体(异硫氰酸荧光素标记) | WB; IHC; ICC; IF. |
LAA684Hu71 | 粘蛋白5B(MUC5B)多克隆抗体(生物素标记) | WB; IHC; ICC. |
MAA684Hu27 | 粘蛋白5B(MUC5B)单克隆抗体 | WB; IHC; ICC; IP. |
MAA684Hu28 | 粘蛋白5B(MUC5B)单克隆抗体 | IHC |
MAA684Hu21 | 粘蛋白5B(MUC5B)单克隆抗体 | WB; IHC; ICC; IP. |
MAA684Hu22 | 粘蛋白5B(MUC5B)单克隆抗体 | WB |
MAA684Hu23 | 粘蛋白5B(MUC5B)单克隆抗体 | WB; IHC; ICC; IP. |
MAA684Hu24 | 粘蛋白5B(MUC5B)单克隆抗体 | WB; IHC; ICC; IP. |
MAA684Hu25 | 粘蛋白5B(MUC5B)单克隆抗体 | WB; IHC; ICC; IP. |
MAA684Hu29 | 粘蛋白5B(MUC5B)单克隆抗体 | WB; IHC; ICC; IP. |
SEA684Hu | 粘蛋白5B(MUC5B)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA684Hu | 粘蛋白5B(MUC5B)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
LMA684Hu | 粘蛋白5B(MUC5B)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
The Journal of Biological Chemistry | The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling [Jcb: 34199] |
The Journal of Biological Chemistry | The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling [Jcb: 247684] |
Respiratory Researh | Pyocyanin-induced mucin production is associated with redox modification of FOXA2 [PubMed: PMC3765780] |
Respirology | Secreted mucins and airway bacterial colonization in non-CF bronchiectasis [PubMed: 26172851] |
American Thoracic Society International Conference Abstracts | Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness [doi:10.1164] |
Ann Am Thorac Soc | Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization [doi:10.1513] |
Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой [10.20538/1682-0363-2017-2-146-158] | |
Allergy | Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps [Pubmed:29802623] |
European Journal of Pharmacology | Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling [Pubmed:29382534] |
Japan Society of Immunology & Allergology in Otolaryngology | インフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響 [10.5648:jjiao.36.7] |
Journal of Investigative Medicine | The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease [Pubmed: 30573494] |
Mucosal Immunology | ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism [Pubmed: 31278375] |
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