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粘蛋白5B(MUC5B)单克隆抗体

Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin

  • 粘蛋白5B(MUC5B)单克隆抗体 产品包装(模拟)
  • 粘蛋白5B(MUC5B)单克隆抗体 产品包装(模拟)
  • MAA684Hu21.jpg Western Blot; Sample: Human Serum Primary Ab: 2µg/mL Mouse Anti-Human MUC5B Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对MUC5B的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别MUC5B。

用法

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

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编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
RPA684Hu02 粘蛋白5B(MUC5B)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA684Hu01 粘蛋白5B(MUC5B)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
CPA684Hu21 粘蛋白5B(MUC5B)卵白蛋白偶联物 Immunogen; SDS-PAGE; WB.
PAA684Hu01 粘蛋白5B(MUC5B)多克隆抗体 WB; IHC; ICC; IP.
PAA684Hu02 粘蛋白5B(MUC5B)多克隆抗体 WB; IHC; ICC; IP.
LAA684Hu81 粘蛋白5B(MUC5B)多克隆抗体(异硫氰酸荧光素标记) WB; IHC; ICC; IF.
LAA684Hu71 粘蛋白5B(MUC5B)多克隆抗体(生物素标记) WB; IHC; ICC.
MAA684Hu27 粘蛋白5B(MUC5B)单克隆抗体 WB; IHC; ICC; IP.
MAA684Hu28 粘蛋白5B(MUC5B)单克隆抗体 IHC
MAA684Hu21 粘蛋白5B(MUC5B)单克隆抗体 WB; IHC; ICC; IP.
MAA684Hu22 粘蛋白5B(MUC5B)单克隆抗体 WB
MAA684Hu23 粘蛋白5B(MUC5B)单克隆抗体 WB; IHC; ICC; IP.
MAA684Hu24 粘蛋白5B(MUC5B)单克隆抗体 WB; IHC; ICC; IP.
MAA684Hu25 粘蛋白5B(MUC5B)单克隆抗体 WB; IHC; ICC; IP.
MAA684Hu29 粘蛋白5B(MUC5B)单克隆抗体 WB; IHC; ICC; IP.
SEA684Hu 粘蛋白5B(MUC5B)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA684Hu 粘蛋白5B(MUC5B)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
LMA684Hu 粘蛋白5B(MUC5B)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
The Journal of Biological Chemistry The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling [Jcb: 34199]
The Journal of Biological Chemistry The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling [Jcb: 247684]
Respiratory Researh Pyocyanin-induced mucin production is associated with redox modification of FOXA2 [PubMed: PMC3765780]
Respirology Secreted mucins and airway bacterial colonization in non-CF bronchiectasis [PubMed: 26172851]
American Thoracic Society International Conference Abstracts Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness [doi:10.1164]
Ann Am Thorac Soc Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization [doi:10.1513]
Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой [10.20538/1682-0363-2017-2-146-158]
Allergy Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps [Pubmed:29802623]
European Journal of Pharmacology  Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling [Pubmed:29382534]
Japan Society of Immunology & Allergology in Otolaryngology インフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響 [10.5648:jjiao.36.7]
Journal of Investigative Medicine The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease [Pubmed: 30573494]
Mucosal Immunology ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism [Pubmed: 31278375]
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