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血管紧张素Ⅱ(AngII)多克隆抗体(生物素标记)

Biotin-Linked Polyclonal Antibody to Angiotensin II (AngII)

Ang-II; Angiotensin-2

  • 血管紧张素Ⅱ(AngII)多克隆抗体(生物素标记) 产品包装(模拟)
  • 血管紧张素Ⅱ(AngII)多克隆抗体(生物素标记) 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对AngII的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别AngII。

用法

Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
CPA005Hu21 血管紧张素Ⅱ(AngII)卵白蛋白偶联物 Immunogen; SDS-PAGE; WB.
PAA005Hu01 血管紧张素Ⅱ(AngII)多克隆抗体 WB; IHC; ICC; IP.
LAA005Hu81 血管紧张素Ⅱ(AngII)多克隆抗体(异硫氰酸荧光素标记) WB; IHC; ICC; IF.
LAA005Hu71 血管紧张素Ⅱ(AngII)多克隆抗体(生物素标记) WB; IHC; ICC.
MAA005Hu22 血管紧张素Ⅱ(AngII)单克隆抗体 WB; IHC; ICC; IP.
CEA005Hu 血管紧张素Ⅱ(AngII)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
CCA005Hu 血管紧张素Ⅱ(AngII)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
LMA005Hu 血管紧张素Ⅱ(AngII)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.
KSA005Hu11 血管紧张素Ⅱ(AngII)检测试剂盒DIY材料(酶联免疫吸附试验法) Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志 参考文献
Nature Medicine Angiotensin-Converting Enzyme 2 Overexpression Remarkably Ameliorated Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition [MolMed: 10_11_liu]
The European Journal of Clinical Investigation Mesangial medium with IgA1 from IgA nephropathy inhibits nephrin expression in mouse podocytes [Wiley: source]
Immunopharmacology and Inflammation Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid [ScienceDirect: S0188440910001049]
Nephrology Effect of aggregated immunoglobulin A1 from immunoglobulin A nephropathy patients on nephrin expression in podocytes [Wiley: source]
PLoS One Angiotensin II and Angiotensin-(1-7) in Paraventricular Nucleus Modulate Cardiac Sympathetic Afferent Reflex in Renovascular Hypertensive Rats [PubMed: PMC3527547]
BioMed Research International Heterogeneous Downregulation of Angiotensin II AT1-A and AT1-B Receptors in Arterioles in STZ-Induced Diabetic Rat Kidneys [Hindawi: 947506]
34 Biglcan is beneficial in angiotensin II induced heart failure by preventing cardiac inflammation and remodeling improving LV function and mortality by preventing transdifferentiation of myofibroblasts [Oxfordjournals: Source]
Pflügers Archiv-European Journal of Physiology SOD1 gene transfer into paraventricular nucleus attenuates hypertension and sympathetic activity in spontaneously hypertensive rats [Pubmed: 23114721]
Eur J Pharmacol. Angiotensin II and vasopressin are involved in the defense system against anaphylactic hypotension in anesthetized rats [Pubmed:24650734]
J Mol Cell Cardiol. Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction [Pubmed:25871829]
Mol Med Rep. High glucose induces activation of the local renin?angiotensin system in glomerular endothelial cells [Pubmed:24337709]
Mol Med Rep. Angiotensin II promotes the progression of human gastric cancer [Pubmed:24424956]
PLOS ONE Intermedin in the Paraventricular Nucleus Attenuates Cardiac Sympathetic Afferent Reflex in Chronic Heart Failure Rats [Pubmed:24709972]
Journal of Vascular Surgery Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice [Pubmed:25037606]
Biochim Biophys Acta. Cathepsin G activity lowers plasma LDL and reduces atherosclerosis [Pubmed:25092171]
Acta Physiologica Superoxide anions in the paraventricular nucleus mediate cardiac sympathetic afferent reflex in insulin resistance rats [Pubmed:25307720]
Neuroscience Letters Administration of exogenous 1,25(OH)2D3 normalizes overactivation of the central renin-angiotensin system in 1α(OH)ase knockout mice [Pubmed:25576706]
34 A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling [PubMed: 26069213]
Life Sci Cardioprotective effects of baicalein on heart failure via modulation of Ca2 [PubMed: 26706290]
Physiological Research Renal Sympathetic Denervation Improves Cardiac Dysfunction [PubMed: 25804096]
Nutrition Effects of Rubus occidentalis extract on blood pressure in subjects with prehypertension: randomized, double-blinded, placebo controlled clinical trial [PubMed: 26740254]
J Am Soc Hypertens Angiotensin-(1–7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats [PubMed: 26428223]
PLoS One. Up ReCavia (Guinea pig )lation of cystathione γ lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol–Caffeine Induced Left Ventricular Hypertrophy in Wistar Kyoto Rats [Pubmed:26963622]
Nutrition Effects of Rubus occidentalis extract on blood pressure in patients with prehypertension: Randomized, double-blinded, placebo-controlled clinical trial [Pubmed:26740254]
Journal of Atherosclerosis and Thrombosis Involvement of Angiotensin II Type 1 and 2 Receptors in Gelatinase ReCavia (Guinea pig )lation in Human Carotid Atheroma in vitro [Pubmed:26947595]
Mol Neurobiol A Therapeutic Insight of Niacin and Coenzyme Q10 Against Diabetic Encephalopathy in Rats [Pubmed:26867655]
Life Sci Cardioprotective effects of baicalein on heart failure via modulation of Ca(2+) handling proteins in vivo and in vitro [Pubmed:26706290]
PLoS One. Paradoxical Sleep Deprivation Causes Cardiac Dysfunction and the Impairment Is Attenuated by Resistance Training. [pubmed:27880816]
Oxidative Medicine and Cellular Longevity Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice [pubmed:27698952]
Journal of the Renin-Angiotensin-Aldosterone System Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin converting enzyme-2/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury [1470320316661871.abstract]
Microvascular Research Pleiotropic effects of survivin in vascular endothelial cells. [pubmed:27373518]
PLOS ONE Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated withActivation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension. [pubmed:27391973]
journal of pharmacological sciences β-Aminoisobutyric acid ameliorates the renal fibrosis in mouse obstructed kidneys via inhibitionof renal fibroblast activation and fibrosis. [pubmed:28433566]
Experimental Animals Ginsenoside Rb1 improves cardiac function and remodeling in heart failure. [pubmed:28367863]
Oncotarget Effects of renal denervation on monocrotaline induced pulmonary remodeling [pubmed:28187460]
The American Journal of Pathology The Renin-Angiotensin System Regulates Neurodegeneration in a Mouse Model of Optic Neuritis [pubmed:28919108]
PLoS One Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy [pubmed:29240788]
Frontiers in Physiology Hydrogen Sulfide Attenuates Atherosclerosis in a Partially Ligated Carotid Artery Mouse model via Regulating Angiotensin Converting Enzyme 2 Expression [pubmed:29066981]
Neurotherapeutics Brain Renin–Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity [Pubmed:29464572]
International Journal of Cardiology ALDH2 protects against alcoholic cardiomyopathy through a mechanism involving the p38 MAPK/CREB pathway and local renin-angiotensin system inhibition in … [Pubmed:29506687]
Neuroscience Angiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats [Pubmed:29684507]
American Journal of Physiology-Renal Physiology Role of (Pro) Renin Receptor in Albumin Overload-Induced Nephropathy in Rats [Pubmed:29846109]
Journal of the American Society of Hypertension Mesenchymal stem cell–derived microvesicles alleviate pulmonary arterial hypertension by regulating renin-angiotensin system [Pubmed:29752040]
Evidence-based Complementary and Alternative Medicine  Acute Biochemical, Cardiovascular, and Autonomic Response to Hyperbaric (4 atm) Exposure in Healthy Subjects [Pubmed:29977313]
Brazilian Journal of Medical and Biological Research Renovascular hypertension increases serum TNF and CX3CL1 in experimental Trypanosoma cruzi infection [Pubmed:29590257]
American Journal of Physiology-Heart and Circulatory Physiology Sex Differences in the Central and Peripheral Manifestations of Ischemia-induced Heart Failure in Rats [Pubmed: 30289294]
Toxicology Mechanisms and Methods Long-term exposure to crotonaldehyde causes heart and kidney dysfunction through induction of inflammatory and oxidative damage in male Wistar rats [Pubmed: 30426860]
Journal of Clinical and Aesthetic Dermatology Detection of Angiotensin II and AT1 Receptor Concentrations in Keloid and Hypertrophic Scar. []
International Journal of Ophthalmology Serum microRNA-221 as a biomarker for diabetic retinopathy in patients associated with type 2 diabetes [Pubmed: 30588418]
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH ACE Gene Plays a Key Role in Reducing Blood Pressure in The Hyperintensive Elderly After Resistance Training [Pubmed: 30908459]
The American Journal of the Medical Sciences T lymphocyte-based renin angiotensin system in obesity []
Journal of Alzheimers Disease Cerebrospinal Fluid Changes in the Renin-Angiotensin System in Alzheimer's Disease [Pubmed: 31594235]
Andrologia Seminal levels of angiotensin II and angiotensin II type 2 receptor expression on spermatozoa in varicocele patients: Relation to fertility status [Pubmed: 31989676]
Molecular Medicine Reports BPA disrupts 17‑estradiol‑mediated hepatic protection against ischemia/reperfusion injury in rat liver by upregulating the Ang II/AT1R signaling pathway [Pubmed: 32319667]
MOLECULAR MEDICINE REPORTS The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta … [Pubmed: 32319652]
Cell Mol Neurobiol Predator Scent-Induced Sensitization of Hypertension and Anxiety-like Behaviors [Pubmed: 33201417]
biochemistry biophysical reports Effect of repetitive potassium iodide on thyroid and cardiovascular functions in elderly rats [Pubmed: 33024842]
bioscience reports Angiotensin II enhances the proliferation of Natural Killer/T-cell lymphoma cells via activating PI3K/Akt signaling pathway [Pubmed: 32969473]
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY A (pro) renin receptor decoy peptide PRO20 protects against adriamycin-induced nephropathy by targeting intrarenal renin-angiotensin system [Pubmed: 32865014]
Acta Endocrinologica-Bucharest THE ROLE OF HIGH FOLLICULAR LEVELS OF ANGIOTENSIN II AND VASCULAR ENDOTHELIAL GROWTH FACTOR IN ANTICIPATING THE … [Pubmed: 32685035]
JOURNAL OF PROTEOME RESEARCH Proteomics and informatics for understanding phases and identifying biomarkers in COVID-19 disease [Pubmed: 32657586]
Scientific Reports Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats [Pubmed: 32616735]
BIOMEDICINE & PHARMACOTHERAPY Semen Brassicae reduces thoracic aortic remodeling, inflammation, and oxidative damage in spontaneously hypertensive rats [Pubmed: 32570115]
CLINICAL AND EXPERIMENTAL HYPERTENSION Hyperinsulinemia rather than insulin resistance itself induces blood pressure elevation in high fat diet-fed rats [Pubmed: 32349626]
Evidence-Based Complementary and Alternative Medicine Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats [Pubmed: 33133215]
Oxidative Medicine and Cellular Longevity Sinapic Acid Attenuates Cardiovascular Disorders in Rats by Modulating Reactive Oxygen Species and Angiotensin Receptor Expression [Pubmed: 32765804]
Nutrition Gut Dysbiosis Contribute to High Fructose Induced Salt Sensitive Hypertension In Sprague-Dawley Rats []
Dikkat Eksikliği Hiperaktivite Bozukluğu Tanısı Olan Anjiyotensin I, II, III, Alamandin peptid, Anjiyotensin Dönüştürücü Enzim (ACE), NADPH Oksidaz Enzim Serum … []
Physiol Behav Low-load resistance training with blood flow restriction prevent renal function decline: The role of the redox balance, angiotensin 1-7 and vasopressin [33340514]
ACTA PHARMACOLOGICA SINICA The vascular endothelial growth factor trap aflibercept induces vascular dysfunction and hypertension via attenuation of eNOS/NO signaling in mice [33303990]
Int J Hypertens The Effects of Renal Nerve Denervation on Blood Pressure and Target Organs in Different Hypertensive Rat Models [33884205]
Physiol Rep (Pro) renin receptor antagonist PRO20 attenuates nephrectomy©\induced nephropathy in rats via inhibition of intrarenal RAS and Wnt/¦Â©\catenin signaling [34057312]
Redox Biology Renovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney [33360353]
Basic and Clinical Neuroscience Paeonol Protects Against Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease [33995926]
researchsquare Ang-(1-7) Protects Skeletal Muscle Function in Aged Mice []
Molecular Medicine Reports Lycium barbarum polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats [34278476]
BMC Musculoskeletal Disorders Ang-(1–7) protects skeletal muscle function in aged mice [34548056]
J Am Heart Assoc Maternal Angiotensin II–Induced Hypertension Sensitizes Postweaning High‐Fat Diet–Elicited Hypertensive Response Through Increased Brain Reactivity in Rat … [34482712]
Biomed Pharmacother Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti … [34736077]
J Am Heart Assoc Loss of the Protective Effect of Estrogen Contributes to Maternal Gestational Hypertension‐Induced Hypertensive Response Sensitization Elicited by Postweaning … [Pubmed:35014859]
J Gerontol A Biol Sci Med Sci Dysregulation of ACE-1 in normal aging and the early stages of Alzheimer's disease [Pubmed:35396835]
Biomedicine & Pharmacotherapy Corynoline protects ang II-induced hypertensive heart failure by increasing PPARα and Inhibiting NF-κB pathway [Pubmed:35658238]
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