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Gremlin 1蛋白(GREM1)多克隆抗体(生物素标记)

Biotin-Linked Polyclonal Antibody to Gremlin 1 (GREM1)

PIG2; CKTSF1B1; DAND2; IHG-2; DAND2; DRM; Increased in high glucose protein 2; Cell proliferation-inducing gene 2 protein; Cysteine knot superfamily 1, BMP antagonist 1

  • Gremlin 1蛋白(GREM1)多克隆抗体(生物素标记) 产品包装(模拟)
  • Gremlin 1蛋白(GREM1)多克隆抗体(生物素标记) 产品包装(模拟)
  • PAC128Mu71.jpg WB图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对GREM1的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别GREM1。

用法

免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Mus musculus (Mouse，小鼠) 应用(仅供研究使用，不用于临床诊断！)
RPC128Mu01 Gremlin 1蛋白(GREM1)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPC128Mu02 Gremlin 1蛋白(GREM1)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
APC128Mu01 Gremlin 1蛋白(GREM1)活性蛋白 Cell culture; Activity Assays.
PAC128Mu01 Gremlin 1蛋白(GREM1)多克隆抗体 WB,IHC
PAC128Mu02 Gremlin 1蛋白(GREM1)多克隆抗体 WB; IHC; ICC; IP.
LAC128Mu81 Gremlin 1蛋白(GREM1)多克隆抗体(异硫氰酸荧光素标记) WB; IHC; ICC; IF.
LAC128Mu71 Gremlin 1蛋白(GREM1)多克隆抗体(生物素标记) WB; IHC; ICC.
SEC128Mu Gremlin 1蛋白(GREM1)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC128Mu Gremlin 1蛋白(GREM1)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
Lung Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension [PubMed: 25926293]
Tumour Biol Overexpression of Gremlin promotes non-small cell lung cancer progression [PubMed: 26392110]
Int J Cardiol Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-term prognosis in suspected and proven acute heart failure patients [PubMed: 26539964]
International Journal of Cardiology Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-termprognosis in suspected and proven acute heart failure patients [Pubmed:26539964]
American Journal of Respiratory Cell and Molecular Biology BMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH [Pubmed:27187737]
J Rheumatol GREM1 Is a Key ReCavia (Guinea pig )lator of Synoviocyte Hyperplasia and Invasiveness [Pubmed:26834210]
European cells & materials The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells. [pubmed:28266688]
Sci Rep. Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients. [pubmed:28327551]
American Journal of Respiratory Cell and Molecular Biology Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial … [rcmb.2015-0402OC]
Molecular Medicine Reports Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells [pubmed:28260028]
Cellular Haemostasis and Platelets Platelets as a novel source of Gremlin-1: Implications for thrombo inflammation [pubmed:27929199]
Scientific Reports Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis [Pubmed: 31053735]
International Journal of Molecular Sciences Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration [Pubmed: 31878307]
American Journal of Physiology-Cell Physiology Suppression of microRNA-23a/b-3p delays the development degenerative joint disease by activating Grem1 and TGF-β/Smad signaling pathway [Pubmed: 32186934]
Inflammopharmacology Protective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa [Pubmed:35441352]
Mol Carcinog CAF‐derived exosomes transmitted Gremlin‐1 promotes cancer progression and decreases the sensitivity of hepatoma cells to sorafenib [Pubmed:35638711]
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