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分泌型卷曲相关蛋白5(SFRP5)单克隆抗体(生物素标记)

Biotin-Linked Monoclonal Antibody to Secreted Frizzled Related Protein 5 (SFRP5)

SARP3; Secreted Apoptosis Related Protein 3; Frizzled-related protein 1b

  • 分泌型卷曲相关蛋白5(SFRP5)单克隆抗体(生物素标记) 产品包装(模拟)
  • 分泌型卷曲相关蛋白5(SFRP5)单克隆抗体(生物素标记) 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对SFRP5的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别SFRP5。

用法

免疫印迹：0.2-2µg/mL;1:500-5000
免疫组织化学：5-20µg/mL;1:50-200
免疫细胞化学：5-20µg/mL;1:50-200
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
RPC842Hu01 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPC842Hu02 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPC842Hu03 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAC842Hu01 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体 WB; IHC; ICC; IP.
PAC842Hu03 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体 WB; IHC; ICC; IP.
PAC842Hu02 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体 WB; IHC; ICC; IP.
LAC842Hu71 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记) WB; IHC; ICC.
MAC842Hu22 分泌型卷曲相关蛋白5(SFRP5)单克隆抗体 WB; IHC; ICC; IP.
LAC842Hu72 分泌型卷曲相关蛋白5(SFRP5)单克隆抗体(生物素标记) WB; IHC; ICC.
SEC842Hu 分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
WEC842Hu 分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法,宽范围) Enzyme-linked immunosorbent assay for Antigen Detection.
HEC842Hu 分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法,高敏型) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC842Hu 分泌型卷曲相关蛋白5(SFRP5)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
Diabetes Research and Clinical Practice Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance [PubMed: 23290274]
European Journal of Clinical Investigation Sfrp5 correlates with insulin resistance and oxidative stress [PubMed: 23398169]
Pediatric Research Balanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children [Pubmed: 24603290]
Clin Endocrinol (Oxf). SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children [Pubmed: 24330025]
The Journal of Clinical Endocrinology & Metabolism Circulating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans [Pubmed: 23185036]
Atherosclerosis Low serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease [Pubmed: 24530778]
PLoS One. Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation [Pubmed:Pmc4072672]
J Clin Endocrinol Metab. Activation of noncanonical Wnt signaling through WNT5A in visceral adipose tissue of obese subjects is related to inflammation [Pubmed:24840810]
Oncology Letters Serum secreted frizzled?related protein 5 levels differentially decrease in patients with hepatitis B virus?associated chronic infection and hepatocellular carcinoma [Pubmed:25120720]
Diabetes Metab Res Rev. Circulating SFRP5 levels are elevated in drug‐na?ve recently diagnosed type 2 diabetic patients as compared with prediabetic subjects and controls [Pubmed:25139699]
Clinical & Experimental Immunology The wingless-related integration site-5a/secreted frizzled-related protein-6 system is dysregulated in human sepsis [Pubmed:25382802]
Diabetes Metab Res Rev Circulating SFRP5 levels are elevated in drug-na [PubMed: 25139699]
J Matern Fetal Neonatal Med Prediction of gestational diabetes mellitus by first trimester serum secreted frizzle-related protein-5 levels [PubMed: 26100762]
Eur J Clin Invest Sfrp5 associates with beta-cell function in humans [Pubmed:27019073]
Osteoporosis International Bone marrow sFRP5 level is negatively associated with bone formation markers [pubmed:27986984]
Diabetes/Metabolism Research and Reviews Plasma Sfrp5 levels correlate with determinants of the metabolic syndrome in Chinese adults [pubmed:28303637]
Cardiovascular Diabetology Inverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study [pubmed:28851362]
Arteriosclerosis, Thrombosis, and Vascular Biology  Effect of SFRP5 (Secreted Frizzled–Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With … [Pubmed:29674475]
Obesity Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans [Pubmed:29427376]
J Bas Res Med Sci Decreased level of the anti-inflammatory adipokines, secreted frizzled-related protein 5 and adiponectin, in high cholesterol diet-induced atherosclerotic rats [article-1-352-en.pdf]
Molecular Biology Reports The effect of serum and follicular fluid secreted frizzle-related protein-5 on in vitro fertilization outcomes in patients with polycystic ovary syndrome [Pubmed: 30194556]
Macrophage LRP1 promotes diet-induced hepatic inflammation and metabolic dysfunction by modulating Wnt signaling []
British Journal Of Nutrition A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile [Pubmed: 30375290]
J Clin Endocrinol Metab Role of wnt5a in Metabolic Inflammation in Humans [Pubmed: 30137542]
Frontiers in Endocrinology Association of Adipocytokines With Carotid Intima Media Thickness and Arterial Stiffness in Obstructive Sleep Apnea Patients [Pubmed: 32300333]
CLINICAL BIOCHEMISTRY Sfrp5/Wnt5a and Leptin/adiponectin levels in the serum and the periarterial adipose tissue of patients with peripheral arterial occlusive disease [Pubmed: 33188773]
Sao Paulo Medical Journal Association of serum levels of secreted frizzled-related protein 5 and Wnt member 5a with glomerular filtration rate in patients with type 2 diabetes mellitus and … [Pubmed: 32491086]
Kidney Blood Press Res Secreted Frizzled-Related Protein 5 Ameliorates Vascular Calcification in a Rat Model of Chronic Kidney Disease through the Wnt/β-Catenin Pathway [34469882]
Cytokine Association of serum uromodulin with adipokines in dependence of type 2 diabetes [34920231]
PLoS One Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study [Pubmed:34990470]
JMIR Res Protoc Investigating New Sensory Methods Related to Taste Sensitivity, Preferences, and Diet of Mother-Infant Pairs and Their Relationship With Body Composition … [Pubmed:35475790]
Diabetology Early Pregnancy Serum Concentration of Secreted Frizzled-Related Protein 4, Secreted Frizzled-Related Protein 5, and Chemerin in Obese Women Who Develop … []
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