Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体
Monoclonal Antibody to Procollagen III N-Terminal Propeptide (PIIINP)
P3NP; N-Propeptide Of Type III Procollagen; Procollagen III Amino Terminal Propeptide
- 编号MAA573Mi22
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)D11
- Ig亚型 IgG2b Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原 -
- 缓冲液成份0.01M 磷酸盐缓冲液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性状液体
- 浓度1mg/mL
- 且适物种-
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 1080 ¥ 2520 ¥ 3600 ¥ 9000 ¥ 36000
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对PIIINP的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别PIIINP。
用法
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
PAA573Mi08 | Ⅲ型前胶原氨基端原肽(PIIINP)多克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi29 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi27 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi22 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi23 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi28 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi24 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi25 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
MAA573Mi21 | Ⅲ型前胶原氨基端原肽(PIIINP)单克隆抗体 | WB; IHC; ICC; IP. |
参考文献
杂志 | 参考文献 |
Molecular Biology Reports | Characterization of the specific and sustained GH1 expression induced by rAAV2/1 in normal adult male rats [PubMed: 20204528] |
Obesity Surgery | A Biomarker Panel for Non-alcoholic Steatohepatitis (NASH) and NASH-Related Fibrosis [PubMed: 20532833] |
Liver Biopsy | Comparison of Five Liver Fibrosis Indexes with Serum Levels of Laminin and N Terminal Peptide of Procollagen Type III in Chronic Hepatitis Patients [Intechopen: 18785] |
Trials | Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial. [Trials: 1745-6215] |
American Journal of Hypertension | Aliskiren and Perindopril Reduce the Levels of Transforming Growth Factor-β in Patients With Non-Diabetic Kidney Disease [Nature: 201214] |
Arthritis Research and Therapy | Raised circulating tenascin-C in rheumatoid arthritis. [PubMed: 23193984] |
American Heart Journal | Serum markers of deranged myocardial collagen turnover: their relation to malignant ventricular arrhythmias in cardioverter-defibrillator recipients with heart failure. [PubMed: 23067911] |
hepatology research | Diagnostic potential of serum direct markers and non-invasive fibrosis models in patients with chronic hepatitis B. [PubMed: 22734888] |
Digestive and Liver Disease | Effects of coffee consumption in chronic hepatitis C: a randomized controlled trial [Pubmed: 23238034] |
Journal of Infectious Diseases | Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis [Pubmed: 23922364] |
International Urogynecology Journal | Prevalence, etiology and risk factors of pelvic organ prolapse in premenopausal primiparous women [Springer: Source] |
Journal of Clinical and Experimental Hepatology | Protective Effects of Norursodeoxycholic Acid Versus Ursodeoxycholic Acid on Thioacetamide-induced Rat Liver Fibrosis [ScienceDirect: S0973688314000073] |
Der Urologe | Retroperitoneale Fibrose [Springer:Source] |
Ultrasound in Obstetrics & Gynecology | The status of the pelvic floor in young primiparous women [Wiley:Source] |
PLoS One. | Clinical significance of markers of collagen metabolism in rheumatic mitral valve disease [Pubmed:24603967] |
Clin Chim Acta. | Serum and urinary procollagen III aminoterminal propeptide as a biomarker of obstructive nephropathy in children [Pubmed:24768785] |
BMC Gastroenterol. | Fast food diet with CCl4 micro-dose induced hepatic-fibrosis-a novel animal model [Pubmed:24884574] |
Toxicology. | DNMT3A silencing RASSF1A promotes cardiac fibrosis through upregulation of ERK1/2 [Pubmed:24945829] |
Southeast Asian J Trop Med Public Health. | Correlation of HBsAg titers with serum fibrotic maker in patients with chronic hepatitis B infection. [Pubmed:24974647] |
The American Journal of Cardiology | Relation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease [Pubmed:25073565] |
Ann Rheum Dis. | B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease [Pubmed:25143523] |
Scientific Reports | Biomarkers and Echocardiographic Predictors of Myocardial Dysfunction in Patients with Hypertension [PubMed: 25747153] |
Int J Mol Sci | The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PubMed: 25984599] |
Viral Hepatitis Journal | The Relationship of the Degree of Hepatic Fibrosis with Hyaluronic Acid, Type 4 Collagen, and Procollagen Type 3 N-Terminal Peptide Levels in Patients with Chronic Viral Hepatitis [Openview: 8A0B8C97D72C61741371F33508760B75] |
International Journal of Experimental Pathology | Pathological characterization and morphometric analysis of hepatic lesions in SHRSP5/Dmcr, an experimental non-alcoholic steatohepatitis model, induced by high-fat and high-cholesterol diet [doi:10.1111] |
Heart Rhythm. | Prognostic value of collagen turnover biomarkers in cardiac resynchronization therapy: A subanalysis of the TRUST CRT randomized trial population [Pubmed:26776557] |
BMJ Open Sport Exerc Med | Procollagen markers in microdialysate can predict patient outcome after Achilles tendon rupture [content:2] |
Inflammation Research | Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy [pubmed:27516211] |
Heart & Vessels | Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR [pubmed:28004175] |
american journal of physiology-renal physiology | Extracellular microRNA signature in chronic kidney disease. [pubmed:28077372] |
Cellular Physiology and Biochemistry | Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy [pubmed:27889753] |
PLoS One. | Procollagen C-Proteinase Enhancer 1 (PCPE-1) as a Plasma Marker of Muscleand Liver Fibrosis in Mice. [pubmed:27458976] |
International Journal of Cardiology | 5-methoxytryptophan is a potential marker for post-myocardial infarction heart failure - apreliminary approach to clinical utility. [pubmed:27526355] |
Transplant Proc | Urinary Type III Procollagen Is Associated With Chronic Allograft Dysfunction and Predicts Graft Survival. [pubmed:28219585] |
Knee Surg Sports Traumatol Arthrosc | Achilles tendon rupture healing is enhanced by intermittent pneumatic compression upregulating collagen type I synthesis [pubmed:28668970] |
Antiviral Therapy | Association of HIV infection with biomarkers of kidney injury and fibrosis in the Multicenter AIDS Cohort Study [pubmed:28054933] |
Molecular Medicine Reports | Profilin‑1 contributes to cardiac injury induced by advanced glycation end‑products in rats [pubmed:28901418] |
Biomarkers Medicial | Relationship of biomarkers of extracellular matrix with myocardial function in Type 2 diabetes mellitus [pubmed:28685602] |
Heart and Vessels | Left ventricular reverse remodeling is not related to biopsy‑detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR [10.1007/s00380-016-0930-y] |
Clinical Infectious Diseases | Matrix Degradation in Human Immunodeficiency Virus Type 1–Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study [10.1093/cid/cix231] |
Cytokine | 12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis. [pubmed:28460256] |
Advanced Healthcare Materials | Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events. [pubmed:29120858] |
American Journal of Kidney Diseases | Urinary Biomarkers of Kidney Tubular Damage and Risk of Cardiovascular Disease and Mortality in Elders [Pubmed:29602632] |
Angiology | The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study [article:10.1007] |
Hernia | Circulating matrix metalloproteinases and procollagen propeptides in inguinal hernia [Pubmed:29484522] |
Cardiovascular Journal of Africa | Assessment of myocardial fibrosis by late gadolinium enhancement imaging and biomarkers of collagen metabolism in chronic rheumatic mitral regurgitation. [Pubmed:29443354] |
Turk Kardiyol Dern Ars. | Association between reverse electrical remodeling and cardiac fibrosis markers in patients with cardiac resynchronization therapy [Pubmed:29512624] |
Кардиоваскулярная терапия и профилактика | N-терминальный пропептид проколлагена III типа в качестве возможного сывороточного маркера фиброза миокарда у больных сахарным диабетом 2 … [:] |
Clinical Infectious Diseases | Improvement in Hepatic Fibrosis Biomarkers Associated with Chemokine Receptor Inactivation through Mutation or Therapeutic Blockade [Pubmed: 30239650] |
Anatolian Journal of Cardiology | microRNA-29a inhibits cardiac fibrosis in Sprague-Dawley rats by downregulating the expression of DNMT3A. [Pubmed: 30297596] |
Contemporary Clinical Trials | Methods to improve the noninvasive diagnosis and assessment of disease severity in children with suspected nonalcoholic fatty liver disease (NAFLD): Study design [Doi: 10.1016/j.cct.2018.10.012] |
Arthritis Research & Therapy | Association of serum levels of fibrosis-related biomarkers with disease activity in patients with IgG4-related disease [Pubmed: 30547825] |
American Journal of Respiratory and Critical Care Medicine | Identification and Modulation of Microenvironment is Crucial for Effective MSC Therapy in Acute Lung Injury [Pubmed: 30521764] |
Direktor: Prof. Dr. med. Andreas Mügge [] | |
Scientific Reports | Low fibrosis biomarker levels predict cardiac resynchronization therapy response [Pubmed: 30988339] |
American Journal of Translational Research | Development and validation of an in vitro 3D model of NASH with severe fibrotic phenotype [Pubmed: 30972180] |
Food and Chemical Toxicology | Gum Acacia mitigates diclofenac nephrotoxicity by targeting monocyte chemoattractant protein-1, complement receptor-1 and pro-apoptotic pathways [Pubmed: 31042592] |
Digestive diseases and sciences | Validation and Refinement of Noninvasive Methods to Assess Hepatic Fibrosis: Magnetic Resonance Elastography Versus Enhanced Liver Fibrosis Index [Pubmed: 31468264] |
Journal of Diabetes Research | Type 2 Diabetes Mellitus and Chronic Heart Failure with Midrange and Preserved Ejection Fraction: A Focus on Serum Biomarkers of Fibrosis [Pubmed: 33224989] |
BMC GASTROENTEROLOGY | Changes in hepatic fibrosis and vitamin D levels after viral hepatitis C eradication using direct-acting antiviral therapy [Pubmed: 33069226] |
european heart journal | A randomized controlled trial of dapagliflozin on left ventricular hypertrophy in people with type two diabetes: the DAPA-LVH trial [Pubmed: 32578850] |
Ассоциации толщины эпикардиального жира и циркулирующих маркеров фиброза миокарда у пациентов с инфарктом миокарда [] | |
J Am Geriatr Soc | Association of Non©\Steroidal Anti©\Inflammatory Drugs with Kidney Health in Ambulatory Older Adults [33305369] |
Aging (Albany NY) | Prognostic potential of cardiac structural and functional parameters and N-terminal propeptide of type III procollagen in predicting cardiac fibrosis one year after?¡ [33431713] |
PeerJ | Effect of vitamin D supplementation in patients with chronic hepatitis C after direct-acting antiviral treatment: a randomized, double-blind, placebo-controlled trial [33614272] |
Open Forum Infectious Diseases | Soluble CD163 Identifies Those at Risk for Increased Hepatic Inflammation & Fibrosis [34104667] |
European Heart Journal | A randomized controlled trial of dapagliflozin on left ventricular hypertrophy in people with type two diabetes [32578850] |
Nutrients | The Effect of Daily Methylsulfonylmethane (MSM) Consumption on High-Density Lipoprotein Cholesterol in Healthy Overweight and Obese Adults: A Randomized … [34684621] |
J Diabetes Res | Association between Markers of Fibrosis and Heart Failure Incidence in Patients with Type 2 Diabetes Mellitus [34778465] |
Scandinavian Cardiovascular Journal | Dual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy [34296634] |
J. Clin. Med | Simple Predictors for Cardiac Fibrosis in Patients with Type 2 Diabetes Mellitus: The Role of Circulating Biomarkers and Pulse Wave Velocity [Pubmed:35628969] |
Biomolecules | Increase in Serum MMP-9 and TIMP-1 Concentrations during Alcohol Intoxication in Adolescents—A Preliminary Study [Pubmed:35625637] |
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