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表皮调节素(EREG)单克隆抗体

Monoclonal Antibody to Epiregulin (EREG)

EPR; ER; Proepiregulin

  • 表皮调节素(EREG)单克隆抗体 产品包装(模拟)
  • 表皮调节素(EREG)单克隆抗体 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对EREG的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别EREG。

用法

免疫印迹：0.2-2µg/mL;1:500-5000
免疫组织化学：5-20µg/mL;1:50-200
免疫细胞化学：5-20µg/mL;1:50-200
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
RPB945Hu02 表皮调节素(EREG)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPB945Hu04 表皮调节素(EREG)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPB945Hu01 表皮调节素(EREG)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPB945Hu03 表皮调节素(EREG)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAB945Hu02 表皮调节素(EREG)多克隆抗体 WB
PAB945Hu01 表皮调节素(EREG)多克隆抗体 WB
PAB945Hu04 表皮调节素(EREG)多克隆抗体 WB; IHC; ICC; IP.
MAB945Hu22 表皮调节素(EREG)单克隆抗体 WB; IHC; ICC; IP.
SEB945Hu 表皮调节素(EREG)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB945Hu 表皮调节素(EREG)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
LMB945Hu 表皮调节素(EREG)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
British Journal of Cancer Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells [Nature: 2012103]
J Pharmacol Exp Ther. Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. [Pubmed: 24309559]
Molecular Carcinogenesis The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines [Pubmed:23625689]
Am J Physiol Gastrointest Liver Physiol. Epiregulin promotes the emergence and proliferation of adult liver progenitor cells. [Pubmed:24812054]
European Review for Medical and Pharmacological Sciences Epiregulin-loaded PLGA nanoparticles increase human keratinocytes proliferation: preliminary data [pubmed:27383296]
Oncotarget Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation [PMC5593575]
American journal of respiratory cell and molecular biology Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis [pubmed:28398769]
International Journal of Cancer Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer [Pubmed: 30252132]
Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways [Doi: 10.1097/PR9.0000000000000718]
Cell proliferation Epiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway [Pubmed: 31454111]
International Journal of Molecular Sciences Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts [Pubmed: 31771279]
Neoplasia Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine [Pubmed: 33212364]
Reprod Sci Compromised Cumulus-Oocyte Complex Matrix Organization and Expansion in Women with PCOS [34748173]
Tissue and Cell MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis [34715618]
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