密封蛋白(OCLN)多克隆抗体
Polyclonal Antibody to Occludin (OCLN)
Tight Junction Protein Occludin TM4 Minus
- 编号PAC228Hu01
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型 IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原 RPC228Hu01-密封蛋白(OCLN)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性状液体
- 浓度500µg/mL
- 且适物种Mus musculus (Mouse,小鼠)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 630 ¥ 1470 ¥ 2100 ¥ 5250 ¥ 21000
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特异性
该抗体是针对OCLN的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别OCLN。
用法
Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
RPC228Hu01 | 密封蛋白(OCLN)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAC228Hu01 | 密封蛋白(OCLN)多克隆抗体 | WB; IHC; ICC; IP. |
MAC228Hu22 | 密封蛋白(OCLN)单克隆抗体 | WB; IHC; ICC; IP. |
SEC228Hu | 密封蛋白(OCLN)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMC228Hu | 密封蛋白(OCLN)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Brain Research | HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9 [ScienceDirect: S0006899311021408] |
Plos one | Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation [PubMed: PMC3688973] |
Journal of Neurotrauma | A new panel of blood biomarkers for the diagnosis of mild traumatic brain injury/concussion in adults [PubMed: 25794137] |
United States Patent Application | Methods for Diagnosis and Treatment of Concussion or Brain Injury [2016:0103140] |
Sci Rep. | Blood Occludin Level as a Potential Biomarker for Early Blood Brain Barrier Damage Following Ischemic Stroke [articles:srep40331] |
Frontiers in Pharmacology | Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal … [Pubmed:29375374] |
Thorax | Fas activation alters tight junction proteins in acute lung injury [Pubmed: 30385692] |
Antioxidants (Basel). | The Effect of Dietary Quercetin on the Glutathione Redox System and Small Intestinal Functionality of Weaned Piglets [Pubmed: 31426309] |
DISEASE MARKERS | Peripheral blood occludin level as a biomarker for preoperative cerebral edema in patients with brain tumors [Pubmed: 32884584] |
Burns Open | Intestinal Permeability in Participants With Thermal Injury: A Case Series From a Prospective, Longitudinal Study (HESTIA) [] |
PLoS One | A comparison of the effects of monotherapy with rosuvastatin, atorvastatin or ezetimibe versus combination treatment with rosuvastatin-ezetimibe and … [34492054] |
CNS Neuroscience & Therapeutics | Higher serum occludin after successful reperfusion Is associated with early neurological deterioration [Pubmed:35338575] |
Impact de l'incorporation d'acides gras à chaine moyenne, de suppléments de levures et d'avoine nue sur la santé intestinale ainsi que sur la consommation … [] |
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