β-位淀粉样前体蛋白裂解酶1(bACE1)单克隆抗体
Monoclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1)
ASP2; Beta Secretase; Memapsin 2; Aspartyl protease 2; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2
- 编号MAA718Hu21
- 物种Homo sapiens (Human，人) 相同的名称，不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)C3
- Ig亚型 IgG1 Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原 RPA718Hu01-β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性状液体
- 浓度1mg/mL
- 且适物种Sus scrofa; Porcine (Pig，猪)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 625 ¥ 1457 ¥ 2082 ¥ 5205 ¥ 20820
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 30μg/ml Mouse Anti-Human bACE1 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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DAB staining on IHC-P;
Samples: Human Cerebrum Tissue;
Primary Ab: 30μg/ml Mouse Anti-Human bACE1 Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对bACE1的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别bACE1。
用法
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Homo sapiens (Human，人) | 应用(仅供研究使用，不用于临床诊断！) |
| RPA718Hu01 | β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA718Hu01 | β-位淀粉样前体蛋白裂解酶1(bACE1)多克隆抗体 | WB; IHC; ICC; IP. |
| MAA718Hu23 | β-位淀粉样前体蛋白裂解酶1(bACE1)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA718Hu24 | β-位淀粉样前体蛋白裂解酶1(bACE1)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA718Hu25 | β-位淀粉样前体蛋白裂解酶1(bACE1)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA718Hu22 | β-位淀粉样前体蛋白裂解酶1(bACE1)单克隆抗体 | WB |
| MAA718Hu21 | β-位淀粉样前体蛋白裂解酶1(bACE1)单克隆抗体 | WB; IHC; ICC; IP. |
| SEA718Hu | β-位淀粉样前体蛋白裂解酶1(bACE1)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA718Hu | β-位淀粉样前体蛋白裂解酶1(bACE1)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
| KSA718Hu01 | β-位淀粉样前体蛋白裂解酶1(bACE1)检测试剂盒DIY材料(酶联免疫吸附试验法) | Main materials for "Do It(ELISA Kit) Yourself" |
参考文献
| 杂志 | 参考文献 |
| Food & Function | Comparative study of the effects of phosphatidylcholine rich in DHA and EPA on Alzheimer’s disease and the possible mechanisms in CHO-APP/PS1 cells and SAMP8 mice [pubmed:29292421] |
| Journal of Functional Foods | EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation [10.1016/j.jff.2017.12.016] |
| Journal of Nutritional Biochemistry | Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet [Pubmed:29986309] |
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice [Pubmed: 32522471] |
| Food Chem Toxicol | Effects of Alcohol Intake on Cognitive Function and ¦Â-amyloid Protein in APP/PS1 Transgenic Mice [33737111] |
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