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M2-型丙酮酸激酶(PKM2)单克隆抗体

Monoclonal Antibody to Pyruvate kinase isozymes M2 (PKM2)

M2PK; PKM; M2-PK; PKM1; CTHBP; OIP3; PK3; PKM; TCB; THBP1; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Cytosolic thyroid hormone-binding protein; Pyruvate Kinase, Muscle

  • M2-型丙酮酸激酶(PKM2)单克隆抗体 产品包装(模拟)
  • M2-型丙酮酸激酶(PKM2)单克隆抗体 产品包装(模拟)
  • M2-型丙酮酸激酶(PKM2)单克隆抗体 Western Blot; Samples: Lane1: A549 cell lysate; Lane2: 293T cell lysate; Lane3: NIH/3T3 cell lysate;
    Primary Ab: 0.2µg/ml Mouse Anti-Human PKM2 Antibody
    Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对PKM2的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别PKM2。

用法

Western blotting: 0.2-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
RPA588Hu01 M2-型丙酮酸激酶(PKM2)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA588Hu02 M2-型丙酮酸激酶(PKM2)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA588Hu03 M2-型丙酮酸激酶(PKM2)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
APA588Hu02 M2-型丙酮酸激酶(PKM2)活性蛋白 Cell culture; Activity Assays.
PAA588Hu02 M2-型丙酮酸激酶(PKM2)多克隆抗体 WB; IHC; IF;FCM
PAA588Hu03 M2-型丙酮酸激酶(PKM2)多克隆抗体 WB; IHC; ICC; IP.
PAA588Hu01 M2-型丙酮酸激酶(PKM2)多克隆抗体 WB,IHC,ICC/IF; FCM
FAA588Hu01 抗M2-型丙酮酸激酶(PKM2)多克隆抗体 Flow cytometry.
FAA588Hu03 抗M2-型丙酮酸激酶(PKM2)多克隆抗体 Flow cytometry.
MAA588Hu24 M2-型丙酮酸激酶(PKM2)单克隆抗体 WB; IHC; ICC; IP.
MAA588Hu22 M2-型丙酮酸激酶(PKM2)单克隆抗体 WB; IHC; ICC; IP.
MAA588Hu23 M2-型丙酮酸激酶(PKM2)单克隆抗体 WB; IHC; ICC; IP.
MAA588Hu21 M2-型丙酮酸激酶(PKM2)单克隆抗体 WB; IHC; ICC; IP.
SEA588Hu M2-型丙酮酸激酶(PKM2)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA588Hu M2-型丙酮酸激酶(PKM2)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
Cancer Research Antigen Presentation by Dendritic Cells in Tumors Is Disrupted by Altered Metabolism that Involves Pyruvate Kinase M2 and Its Interaction with SOCS3 [AACR: 70189]
Molecular BioSystems Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer [Pubmed:25483567]
Tumour Biol M2 isoform of pyruvate kinase (PKM2) is upregulated in Kazakh’s ESCC and promotes proliferation and migration of ESCC cells [PubMed: 26404132]
Oncotarget Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis [Pubmed:29707118]
Journal of Neurotrauma Acteoside improves muscle atrophy and motor function by inducing new myokine secretion in chronic spinal cord injury [Pubmed: 30318996]
Cell Reports Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway [Pubmed: 32049010]
Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC) []
Cancer Cell International Bufalin Induced Mitochondrial Dysfunction Promotes Apoptosis of Glioma Cells by Regulating Annexin A2 and DRP1 Proteins []
Cancer Cell Int Bufalin induces mitochondrial dysfunction and promotes apoptosis of glioma cells by regulating Annexin A2 and DRP1 protein expression [34376212]
Life (Basel) Putative Association between Low Baseline Gene Expression in the Peripheral Blood and Clinical Remission in Rheumatoid Arthritis Patients Treated with Tofacitinib [34947916]
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