核因子κB受体激活因子配体(RANkL)单克隆抗体
Monoclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
CD254; TNFSF11; ODF; OPGL; TRANCE; HRANKL2; SOdf; Tumor Necrosis Factor(ligand)superfamily Member 11; TNF-related activation-induced cytokine
- 编号MAA855Ra24
- 物种Rattus norvegicus (Rat,大鼠) 相同的名称,不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)C10
- Ig亚型 IgG2a Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原 RPA855Ra01-核因子κB受体激活因子配体(RANkL)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性状液体
- 浓度1mg/mL
- 且适物种-
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 652 ¥ 1520 ¥ 2172 ¥ 5430 ¥ 21720
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对RANkL的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别RANkL。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
编号 | 适用物种:Rattus norvegicus (Rat,大鼠) | 应用(仅供研究使用,不用于临床诊断!) |
APA855Ra61 | 核因子κB受体激活因子配体(RANkL)活性蛋白 | Cell culture; Activity Assays. |
RPA855Ra01 | 核因子κB受体激活因子配体(RANkL)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA855Ra01 | 核因子κB受体激活因子配体(RANkL)多克隆抗体 | WB; IHC; ICC; IP. |
MAA855Ra24 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
MAA855Ra26 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
MAA855Ra22 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
MAA855Ra23 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
MAA855Ra21 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
LAA855Ra76 | 核因子κB受体激活因子配体(RANkL)单克隆抗体(生物素标记) | WB; IHC; ICC. |
SEA855Ra | 核因子κB受体激活因子配体(RANkL)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA855Ra | 核因子κB受体激活因子配体(RANkL)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
LMA855Ra | 核因子κB受体激活因子配体(RANkL)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
PSA855Ra01 | 核因子κB受体激活因子配体(RANkL)抗体对 | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
KSA855Ra01 | 核因子κB受体激活因子配体(RANkL)检测试剂盒DIY材料(酶联免疫吸附试验法) | Main materials for "Do It (ELISA Kit) Yourself". |
参考文献
杂志 | 参考文献 |
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PLOS One | Adipokines in Psoriatic Arthritis Patients: The Correlations with Osteoclast Precursors and Bone Erosions [PubMed: PMC3483160] |
Arthritis Research&Therapy | Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes [PubMed: PMC3672788] |
International Journal of Oral and Maxillofacial Surgery | The effects of chronic zoledronate usage on the jaw and long bones evaluated using RANKL and osteoprotegerin levels in an animal model [Pubmed: 23522850] |
AGE | Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells [Pubmed: 24687841] |
Food Science & Nutrition | Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7 [Onlinelibrary: fsn3.109] |
Food Sci Nutr. | Effects and mechanisms of 8‐prenylnaringenin on osteoblast MC3T3‐E1 and osteoclast‐like cells RAW264. 7 [Pubmed:Pmc4221832] |
Journal of Investigative Surgery | Effect of Nicotine on RANKL and OPG and Bone Mineral Density [Pubmed:24830656] |
Int J Mol Med. | Effects of icariin on the regulation of the OPG?RANKL?RANK system are mediated through the MAPK pathways in IL?1β?stimulated human SW1353 chondrosarcoma … [Pubmed:25270538] |
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oncotarget | MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone [PubMed: 26053181] |
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BMJ Journals | SAT0003 The Role of 12/15-Lipoxygenase in The Pathogenesis of Osteoporosis in Mice [content:75] |
Japanese Society for Bone and Mineral Research | Allogeneic yet major histocompatibility complex‑matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced trabecular bone [article:10.1007] |
ONCOLOGY LETTERS | Assessment of bone metabolism and biomechanical properties of the femur, following treatment with anastrozole and letrozole in an experimental model of menopause [ol.2017.6596] |
Journal of Clinical Periodontology | Peroxisome proliferator‐activated receptor γ plays dual roles on experimental periodontitis in rats [Pubmed:29574908] |
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International Immunopharmacology | Switched memory B cells promote alveolar bone damage during periodontitis: An adoptive transfer experiment [Pubmed:30015235] |
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Journal of Bone and Mineral Metabolism | Allogeneic yet major histocompatibility complex-matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced … [Pubmed:28766138] |
Experimental and Therapeutic Medicine | Liraglutide exerts a bone‑protective effect in ovariectomized rats with streptozotocin‑induced diabetes by inhibiting osteoclastogenesis [Pubmed:29805533] |
Bone | The sole and combined effect of simvastatin and platelet rich fibrin as a filling material in induced bone defect in tibia of albino rats [Pubmed: 30208342] |
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Bone Research | NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts [Pubmed: 30455992] |
Journal of International Dental and Medical Research | Alendronate Effect in RANKL Concentration at Ovariectomized Sprague Dawley Rat. [] |
Bone | Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process [Pubmed: 30797058] |
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | Evaluation of therapeutic effects of teriparatide in a rat model of zoledronic acid-induced bisphosphonate-related osteonecrosis [] |
Rheumatology International | Comparison of RANKL expression, inflammatory markers, and cardiovascular risk in patients with acute coronary syndrome with and without rheumatoid arthritis [Pubmed: 31297563] |
World Journal of Pediatrics | Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis [Pubmed: 31641939] |
Bone | Mice lacking plastin-3 display a specific defect of cortical bone acquisition [Pubmed: 31678489] |
BIOSCIENCE REPORTS | IL-38 restrains inflammatory response of collagen-induced arthritis in rats via SIRT1/HIF-1α signaling pathway [Pubmed: 32347300] |
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Biomed Pharmacother | Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis [Pubmed:35453007] |
Phytomedicine | Transcriptomic profiling revealed the role of apigenin-4′-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK … [Pubmed:35660352] |
Med Science | Identification of marker proteins in preterm and term birth: Relationship of rankl and HSP70 in the cord blood [] |
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