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含Ⅲ型纤连蛋白域蛋白5(FNDC5)多克隆抗体

Polyclonal Antibody to Fibronectin Type III Domain Containing Protein 5 (FNDC5)

FRCP2; Irisin; Fibronectin type III repeat-containing protein 2

  • 含Ⅲ型纤连蛋白域蛋白5(FNDC5)多克隆抗体 产品包装(模拟)
  • 含Ⅲ型纤连蛋白域蛋白5(FNDC5)多克隆抗体 产品包装(模拟)
  • PAN576Mu01.jpg Figure. Western Blot; Sample: Recombinant FNDC5, Mouse.
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对FNDC5的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别FNDC5。

用法

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Mus musculus (Mouse，小鼠) 应用(仅供研究使用，不用于临床诊断！)
APN576Mu61 含Ⅲ型纤连蛋白域蛋白5(FNDC5)活性蛋白 Cell culture; Activity Assays.
APN576Mu01 含Ⅲ型纤连蛋白域蛋白5(FNDC5)活性蛋白 Cell culture; Activity Assays.
RPN576Mu01 含Ⅲ型纤连蛋白域蛋白5(FNDC5)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPN576Mu02 含Ⅲ型纤连蛋白域蛋白5(FNDC5)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAN576Mu02 含Ⅲ型纤连蛋白域蛋白5(FNDC5)多克隆抗体 WB; IHC; ICC; IP.
PAN576Mu01 含Ⅲ型纤连蛋白域蛋白5(FNDC5)多克隆抗体 WB; IHC; ICC; IP.
SEN576Mu 含Ⅲ型纤连蛋白域蛋白5(FNDC5)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMN576Mu 含Ⅲ型纤连蛋白域蛋白5(FNDC5)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
Diabetes Research and Clinical Practice Serum irisin levels in new-onset type 2 diabetes [PubMed: 23369227]
Journal of diabetes and its complications Lower circulating irisin is associated with type 2 diabetes mellitus [Pubmed: 23619195]
Horm Metab Res. Inconsistency in circulating irisin levels: what is really happening [Pubmed:24459033]
Int J Obes (Lond). Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice [Pubmed:25199621]
Molecular and Cellular Endocrinology Fenofibrate (PPARalpha agonist) induces beige cell formation in subcutaneous white adipose tissue from diet-induced male obese mice [Pubmed:25576856]
journal of diabetes Lower irisin level in patients with type 2 diabetes mellitus: A case-control study and meta-analysis [PubMed: 25494632]
The Journal of Maternal-Fetal & Neonatal Medicine Maternal circulating levels of irisin in intrahepatic cholestasis of pregnancy [PubMed: 26689349]
Hormone and Metabolic Research Lower Circulating Irisin Level in Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis [Pubmed:27300472]
Nature Reviews Endocrinology Physiology and role of irisin in glucose homeostasis. [pubmed:28211512]
Journal of Molecular and Cellular Cardiology Irisin improves perivascular adipose tissue dysfunction via regulation of the heme oxygenase-1/adiponectin axis in diet-induced obese mice [pubmed:27638193]
Biochemical and Biophysical Research Communications Irisin stimulates cell proliferation and invasion by targeting the PI3K/AKT pathway in human hepatocellular carcinoma [pubmed:28867187]
PLoS One Differential actions of PPAR-α and PPAR-β/δ on beige adipocyte formation: A study in the subcutaneous white adipose tissue of obese male mice [Pubmed:29351550]
International Brazilian Journal of Urology The Diagnostic Value of FNDC5/Irisin in Renal Cell Cancer. [Pubmed:29522296]
Redox Biology Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative … [Doi: 10.1016/j.redox.2018.10.019]
Antioxidants & redox signaling Low serum irisin concentration is associated with poor outcomes in patients with acute pancreatitis and irisin administration protects against experimental acute … [Pubmed: 31250660]
Journal of Maternal-Fetal & Neonatal Medicine Maternal serum, placental, and umbilical venous blood irisin levels in intrahepatic cholestasis of pregnancy [Pubmed: 31590596]
Biomed Pharmacother Identification of irisin as a therapeutic agent that inhibits oxidative stress and fibrosis in a murine model of chronic pancreatitis [Pubmed: 32199226]
Irisin Improves Autophagy of Aged Hepatocytes via Increasing Telomerase Activity in Liver Injury [Pubmed: 31976032]
Serum Irisin Predicts Posthepatectomy Complications in Patients with Hepatocellular Carcinoma [Pubmed: 31976024]
DOMESTIC ANIMAL ENDOCRINOLOGY The myokine Irisin: localization and effects in swine late medium and large antral ovarian follicle [Pubmed: 33120167]
Journal of Biomaterials and Tissue Engineering The Combination of Aerobic and Resistance Exercise Induces Weight Loss via the PGC-1α/Irisin/UCP-1 Pathway []
Evaluation of a recombinant bacillus calmette-guérin vaccine expressing P39-L7/L12 of Brucella melitensis: An immunization strategy against brucellosis in BALB/c … []
Eur Rev Med Pharmacol Sci Salivary Irisin: potential inflammatory biomarker in recurrent apthous stomatitis patients [33755963]
Metabolites Pattern of Adiponectin, Osteocalcin, Irisin, FGF-21, and MCP-1 According to the Body Size Phenotype: Could They Be Markers of Metabolic Health in Mexican-Mestizo … [34822430]
Eat Weight Disord Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice [34370270]
Ir J Med Sci Eight-week exercise program improved the quality of life of Alzheimer's patients through functional, cognitive, and biochemical parameters [Pubmed:35604540]
Biomed Pharmacother Irisin attenuates sepsis-induced cardiac dysfunction by attenuating inflammation-induced pyroptosis through a mitochondrial ubiquitin ligase-dependent … [Pubmed:35653888]
Journal of King Saud University - Science Interaction of nitric oxide synthase and mitochondrial ATP-sensitive potassium channels in protective impacts of combination therapy with irisin … []
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