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胰岛素(INS)多克隆抗体

Polyclonal Antibody to Insulin (INS)

  • 胰岛素(INS)多克隆抗体 产品包装(模拟)
  • 胰岛素(INS)多克隆抗体 产品包装(模拟)
  • 胰岛素(INS)多克隆抗体 DAB staining on IHC-P; Samples: Porcine Pancreas Tissue; Primary Ab: 20µg/ml Rabbit Anti-Porcine INS Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • PAA448Po02.jpg WB图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对INS的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别INS。

用法

免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Sus scrofa; Porcine (Pig，猪) 应用(仅供研究使用，不用于临床诊断！)
RPA448Po02 胰岛素(INS)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA448Po01 胰岛素(INS)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
CPA448Po21 胰岛素(INS)卵白蛋白偶联物 Immunogen; SDS-PAGE; WB.
PAA448Po02 胰岛素(INS)多克隆抗体 WB; IHC; ICC; IP.
PAA448Po01 胰岛素(INS)多克隆抗体 WB; IHC; ICC; IP.
CEA448Po 胰岛素(INS)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA448Po 胰岛素(INS)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.
KSA448Po11 胰岛素(INS)检测试剂盒DIY材料(酶联免疫吸附试验法) Main materials for "Do It (ELISA Kit) Yourself".

参考文献

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Acta Pharmacologica Sinica Huperzine A ameliorates obesity-related cognitive performance impairments involving neuronal insulin signaling pathway in mice [Pubmed: 31213670]
Biochemistry Protective Effect of Peroxiredoxin 6 Against Toxic Effects of Glucose and Cytokines in Pancreatic RIN-m5F β-Cells []
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Diabetes-Metabolism Research and Reviews Liraglutide Combined with Human Umbilical Cord Mesenchymal Stem Cell Transplantation inhibits beta‐cells apoptosis via mediating the ASK1/JNK/BAX pathway in [Pubmed: 31411368]
Phytomedicine Baicalin ameliorates hepatic insulin resistance and gluconeogenic activity through inhibition of p38 MAPK/PGC-1α pathway []
Naunyn-Schmiedebergs Archives of Pharmacology Coptisine ameliorates renal injury in diabetic rats through the activation of Nrf2 signaling pathway [Pubmed: 31420722]
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Molecular and cellular endocrinology Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway [Pubmed: 31647955]
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Biomedicine & Pharmacotherapy Propolis modulates the gut microbiota and improves the intestinal mucosal barrier function in diabetic rats [Pubmed: 31545258]
International Journal of Endocrinology miR-29a Negatively Affects Glucose-Stimulated Insulin Secretion and MIN6 Cell Proliferation via Cdc42/β-Catenin Signaling [Pubmed: 31662747]
Food & Function Depolymerized RG-I enriched pectin from citrus segment membrane modulates gut microbiota, increases SCFAs production, promotes the growth of Bifidobacterium … [Pubmed: 31778135]
Life Sciences P-Coumaric acid alleviates experimental diabetic nephropathy through modulation of toll like receptor-4 in rats [Pubmed: 31629762]
Journal of Ovarian Research Baicalin ameliorates polycystic ovary syndrome through AMP-activated protein kinase [Pubmed: 31722718]
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Brain Research Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice [Pubmed: 31672472]
Journal of Ethnopharmacology San-Huang-Tang protects obesity/diabetes induced NAFLD by upregulating PGC-1α/PEPCK signaling in obese and galr1 knockout mice models [Pubmed: 31843573]
Journal of Hazardous Materials Triphenyl phosphate causes a sexually dimorphic metabolism dysfunction associated with disordered adiponectin receptors in pubertal mice [Pubmed: 31796355]
Journal of Steroid Biochemistry and Molecular Biology SerpinB1 promotes the proliferation of porcine pancreatic stem cells through the STAT3 signaling pathway [Pubmed: 31785377]
Journal of dermatological treatment Liraglutide improved inflammation via mediating IL-23/Th-17 pathway in obese diabetic mice with psoriasiform skin [Pubmed: 31868553]
Nutrients Rotundic Acid Protects against Metabolic Disturbance and Improves Gut Microbiota in Type 2 Diabetes Rats [Pubmed: 31887996]
JOURNAL OF DAIRY SCIENCE Decreased amylolytic microbes of the hindgut and increased blood glucose implied improved starch utilization in the small intestine by using rumen-protected leucine … [Pubmed: 32113753]
Biomed Pharmacother Composite probiotics alleviate type 2 diabetes by regulating intestinal microbiota and inducing GLP-1 secretion in db/db mice [Pubmed: 32035395]
Frontiers in Endocrinology Hyperbaric oxygen ameliorates insulin sensitivity by increasing GLUT4 expression in skeletal muscle and stimulating UCP1 in brown adipose tissue in T2DM … [Pubmed: 32082261]
Cell Physiol Biochem Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model. [Pubmed: 31972071]
JOURNAL OF FOOD SCIENCE Beneficial effects of Aronia melanocarpa berry extract on hepatic insulin resistance in type 2 diabetes mellitus rats [Pubmed: 32249934]
Journal of Diabetes Research Roux-en-Y Gastric Bypass in Obese Diabetic Rats Promotes Autophagy to Improve Lipid Metabolism through mTOR/p70S6K Signaling Pathway [Pubmed: 32309446]
Brain Research Electroacupuncture improves cognitive deficits and insulin resistance in an OLETF rat model of Al/D-gal induced aging model via the PI3K/Akt signaling pathway [Pubmed: 32304687]
endocrine journal Mice with nucleus tractus solitarius injury induced by chronic restraint stress present impaired ability to raise blood glucose and glucagon levels when blood glucose … [Pubmed: 32249244]
Frontiers in Endocrinology RFRP-3, the Mammalian Ortholog of GnIH, Is a Novel Modulator Involved in Food Intake and Glucose Homeostasis [Pubmed: 32328034]
Antioxidants Effects of Allicin on Pathophysiological Mechanisms during the Progression of Nephropathy Associated to Diabetes [Pubmed: 33203103]
Nature Communications AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis [Pubmed: 33199780]
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES Evaluation of the hypoglycemic effect of exendin-4's new oral self-nanoemulsifying system in rats [Pubmed: 33197556]
BIOLOGICAL RESEARCH Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance … [Pubmed: 33109277]
FASEB JOURNAL Irradiation of carotid baroreceptor with low‐intensity pulsed ultrasound exerts different metabolic protection in perirenal, epididymal white adipose tissue and … [Pubmed: 32954574]
Biol Res Palmatine ameliorates high fat diet induced impaired glucose tolerance [Pubmed: 32928312]
ENDOCRINE Thioredoxin-interacting protein: a critical link between autophagy disorders and pancreatic β-cell dysfunction [Pubmed: 32892310]
DIABETOLOGIA Adiponectin treatment improves insulin resistance in mice by regulating the expression of the mitochondrial-derived peptide MOTS-c and its response to exercise via … [Pubmed: 32880686]
AMERICAN JOURNAL OF PATHOLOGY Insulin promotes corneal nerve repair and wound healing in type 1 diabetic mice by enhancing Wnt/β-catenin signaling [Pubmed: 32858016]
MEDIATORS OF INFLAMMATION Aplysin Retards Pancreatic Necrosis and Inflammatory Responses in NOD Mice by Stabilizing Intestinal Barriers and Regulating Gut Microbial Composition [Pubmed: 32801992]
EUROPEAN JOURNAL OF PHARMACOLOGY Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways [Pubmed: 32758573]
ARCHIVES OF GYNECOLOGY AND OBSTETRICS MiRNAs expression profiling of rat ovaries displaying PCOS with insulin resistance [Pubmed: 32757043]
CHEMICO-BIOLOGICAL INTERACTIONS Modulatory role of imatinib mesylate on pancreatic β-cells' secretory functions in an STZ rat model of diabetes mellitus [Pubmed: 32710900]
Mol Med Electroacupuncture alleviates polycystic ovary syndrome-like symptoms through improving insulin resistance, mitochondrial dysfunction, and endoplasmic … [Pubmed: 32698821]
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Highly Branched RG-I Domain Enrichment are Indispensable for Pectin Mitigating Against High-Fat Diet-Induced Obesity [Pubmed: 32633953]
Scientific Reports Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats [Pubmed: 32616735]
J Endocrinol Invest Activation of central galanin receptor 2 mitigated insulin resistance in adipocytes of diabetic rats [Pubmed: 32588381]
J Chem Neuroanat The neuroprotective effect of simvastatin on the cerebellum of experimentally-induced diabetic rats through klotho upregulation: An immunohistochemical study [Pubmed: 32479899]
Journal of Diabetes Research Regulation and Mechanism of miR-518d through the PPARα-Mediated NF-κB Pathway in the Development of Gestational Diabetes Mellitus [Pubmed: 33123597]
Journal of Cellular and Molecular Medicine Cooperative effects of galanin and leptin on alleviation of insulin resistance in adipose tissue of diabetic rats [Pubmed: 32395890]
BioMed Research International Pathophysiological Changes in Female Rats with Estrous Cycle Disorder Induced by Long-Term Heat Stress [Pubmed: 32685488]
Frontiers in Pharmacology MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFA [Pubmed: 32760272]
Iranian Journal of Basic Medical Sciences Therapeutic effects of organic zinc on reproductive hormones, insulin resistance and mTOR expression as a novel component in a rat model of PCOS []
Nutrition & Metabolism Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut … []
Journal of Functional Foods Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats []
Comparative transcriptomic and metabolomic analysis reveals pectoralis highland adaptation across altitudinal songbirds []
The effects of different intensity endurance and resistance exercise on diabetic-related blood profiles in impaired glucose tolerance mice []
Cell Death & Disease Phosphorylation of eIF2¦Á signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner [33318479]
Ther Adv Chronic Dis Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice [33294147]
Physiol Behav Time-restricted feeding attenuates gluconeogenic activity through inhibition of PGC-1¦Á expression and activity [33412190]
PLoS Genetics Physiological and genetic convergence supports hypoxia resistance in high-altitude songbirds [33370292]
Mol Med Rep N1?methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC?1¦Á signaling pathway [33576435]
Arch Endocrinol Metab Inverse association of plasma hydrogen sulfide levels with visceral fat area among Chinese young men: a cross-sectional study [33740335]
Sci Rep Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats [33833309]
PeerJ miR-155-5p upregulation ameliorates myocardial insulin resistance via mTOR signaling in chronic alcohol drinking rats [33868799]
JOURNAL OF FOOD BIOCHEMISTRY Identification of curcumin as a potential ¦Á©\glucosidase and dipeptidyl©\peptidase 4 inhibitor: Molecular docking study, in vitro and in vivo biological evaluation [33817806]
JOURNAL OF NUTRITIONAL BIOCHEMISTRY Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver?¡­ [33915261]
Cell Metab TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease [34107313]
Dapagliflozin: a Sodium-glucose Cotransporter 2 Inhibitor, Attenuates Angiotensin II-induced Cardiac Fibrotic Remodeling by Regulating TGF¦Â1/Smad ¡­ [34116674]
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY Different Ratios of Corn and Coconut Oil Blends in High©\Fat Diets Influence Fat Deposition without Altering Metabolic Biomarkers in Male Rats []
Journal of Alzheimer's disease DAla2-GIP-GLU-PAL Protects Against Cognitive Deficits and Pathology in APP/PS1 Mice by Inhibiting Neuroinflammation and Up-regulating cAMP/PKA/CREB?¡­ []
International Journal of Diabetes in Developing Countries Investigation of extracellular matrix genes associated with Alzheimer's disease in the hippocampus of experimental diabetic model rats []
researchsquare Ficus deltoidea ameliorates biochemical, hormonal, and histomorphometric changes in letrozole-induced polycystic ovarian syndrome rats []
Cells Tissues Organs Intermittent Fasting Attenuates High Fat Diet-Induced Cerebellar Changes in Rats: Involvement of TNFα, autophagy and oxidative stress [34551416]
Experimental Biology and Medicine Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats [34550826]
Phytomedicine Baicalin protects against insulin resistance and metabolic dysfunction through activation of GALR2/GLUT4 signaling [34923235]
Pharmacol Res Lactobacillus acidophilus ameliorates obesity in mice through modulation of gut microbiota dysbiosis and intestinal permeability [34896249]
Eat Weight Disord Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice [34370270]
Food Chem Toxicol Combined treatment of sinapic acid and ellagic acid attenuates hyperglycemia in streptozotocin-induced diabetic rats [34329744]
Eur J Pharmacol Spexin ameliorates skeletal muscle insulin resistance through activation of GAL2 receptor [Pubmed:34973950]
Surgical Endoscopy The effect of bariatric surgery on the expression of Growth Differentiation Factor-15/Macrophage-Inhibitory Cytokine-1 (GDF-15/MIC-1) in rat [Pubmed:35029766]
Arch Biochem Biophys ATP6V1H deficiency impairs glucose tolerance by augmenting endoplasmic reticulum stress in high fat diet fed mice [Pubmed:34990584]
Environ Sci Pollut Res Int Environmental exposure to low-dose perfluorohexanesulfonate promotes obesity and non-alcoholic fatty liver disease in mice fed a high-fat diet [Pubmed:35217953]
Naunyn Schmiedebergs Arch Pharmacol Intragastric safflower yellow and its main component HSYA improve leptin sensitivity before body weight change in diet-induced obese mice [Pubmed:35201390]
PLoS One A cross-sectional comparative study on the effects of body mass index and exercise/sedentary on serum asprosin in male college students [Pubmed:35381008]
Cell Death & Disease Hepatic deficiency of selenoprotein S exacerbates hepatic steatosis and insulin resistance [Pubmed:35347118]
Endocr J A novel anti-obesity mechanism for liraglutide by improving adipose tissue leptin resistance in high-fat diet-fed obese mice [Pubmed:35705299]
Antioxidants Antioxidant Effect of Tyr-Ala Extracted from Zein on INS-1 Cells and Type 2 Diabetes High-Fat-Diet-Induced Mice [Pubmed:35740008]
Mol Cell Endocrinol Treatment with spexin mitigates diet-induced hepatic steatosis in vivo and in vitro through activation of galanin receptor 2 [Pubmed:35654225]
Biofabrication Dual-core coaxial bioprinting of double-channel constructs with a potential for perfusion and interaction of cells [Pubmed:35616388]
Ecotoxicology and Environmental Safety Constitutional delay of growth and puberty in female mice is induced by circadian rhythm disruption in utero [Pubmed:35679725]
SAUDI J BIOL SCI Aqueous Ajwa dates seeds extract improves memory impairment in type-2 diabetes mellitus rats by reducing blood glucose levels and enhancing brain … [Pubmed:35531250]
Saudi Pharmaceutical Journal Sukkari dates seed improves type-2 diabetes mellitus-induced memory impairment by reducing blood glucose levels and enhancing brain cholinergic … [Pubmed:35812141]
Turk J Diab Obes An Investigation of the Effect of Curcumin on Fructose-Induced Metabolic Syndrome Rat Models []
Journal of Drug Delivery Science and Technology Miglitol-PMO nanoparticles, an alpha-glucosidase inhibitor, has prolonged action on blood glucose level in diabetic rats []
Genes & Diseases Prolonged control of insulin-dependent diabetes via intramuscular expression of plasmid-encoded single-strand insulin analogue []
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