干扰素β(IFNb)多克隆抗体
Polyclonal Antibody to Interferon Beta (IFNb)
IFNB1; IFN-B; IFB; IFF; IFNB; Interferon Beta 1 Fibroblast
- 编号PAA222Mu02
- 物种Mus musculus (Mouse,小鼠) 相同的名称,不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型 IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原 -
- 缓冲液成份磷酸盐缓冲液(pH7.4,含有0.02% NaN3和50%甘油)
- 性状液体
- 浓度500µg/mL
- 且适物种-
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 583 ¥ 1361 ¥ 1944 ¥ 4860 ¥ 19440
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对IFNb的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别IFNb。
用法
免疫印迹:0.2-2µg/mL;1:250-2500
免疫组织化学:5-20µg/mL;1:25-100
免疫细胞化学:5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
编号 | 适用物种:Mus musculus (Mouse,小鼠) | 应用(仅供研究使用,不用于临床诊断!) |
EPA222Mu61 | 干扰素β(IFNb)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APA222Mu61 | 干扰素β(IFNb)活性蛋白 | Cell culture; Activity Assays. |
RPA222Mu02 | 干扰素β(IFNb)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APA222Mu01 | 干扰素β(IFNb)活性蛋白 | Cell culture; Activity Assays. |
RPA222Mu01 | 干扰素β(IFNb)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA222Mu02 | 干扰素β(IFNb)多克隆抗体 | WB; IHC; ICC; IP. |
PAA222Mu01 | 干扰素β(IFNb)多克隆抗体 | WB; IHC; ICC; IP. |
SEA222Mu | 干扰素β(IFNb)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
MEA222Mu | 干扰素β(IFNb)检测试剂盒(酶联免疫吸附试验法,小样本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA222Mu | 干扰素β(IFNb)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
20 | Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway [PubMed: 21355876] |
Journal of General Virology | Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKε and DDX3. [Sgm: 9182080] |
Biochemical and Biophysical Research Communications | Impaired TLR3/IFN-β signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: Relevance to the severity of liver damage [ScienceDirect: S0006291X09019822] |
PLoS One | Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys [PubMed: PMC3757038] |
PLoS Neglected Tropical Diseases | Innate Immune Response to Rift Valley Fever Virus in Goats [PubMed: PMC3335883] |
BioMed Research International | Low pH Environmental Stress Inhibits LPS and LTA-Stimulated Proinflammatory Cytokine Production in Rat Alveolar Macrophages [Pubmed: 24288685] |
Vet Microbiol. | An attenuated EIAV strain and its molecular clone strain differentially induce the expression of Toll-like receptors and type-I interferons in equine monocyte-derived macrophages. [Pubmed: 23850441] |
Food and Chemical Toxicology | Scoparone attenuates d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure through inhibition of toll-like receptor 4 signaling in mice [Pubmed: 23535186] |
Veterinary immunology and immunopathology | Experimental model of equine alveolar macrophage stimulation with TLR ligands [Pubmed: 23815824] |
American journal of respiratory cell and molecular biology | Training Modifies Innate Immune Responses in Blood Monocytes and in Pulmonary Alveolar Macrophages [Pubmed: 24502337] |
FEBS Lett. | Mannan binding lectin attenuates double-stranded RNA-mediated TLR3 activation and innate immunity [Pubmed:24530528] |
Veterinary Research | Infection of equine monocyte-derived macrophages with an attenuated equine infectious anemia virus (EIAV) strain induces a strong resistance to the infection by a virulent EIAV strain [Pubmed:25106750] |
PLOS Neglected Tropical Diseases | MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production [Pubmed:25122182] |
Veterinary Research | The innate immune response of equine bronchial epithelial cells is altered by training [Pubmed:25595212] |
molecular and celluar biology | SOCS3 Drives Proteasomal Degradation of TBK1 and Negatively Regulates Antiviral Innate Immunity [PubMed: 25939384] |
Arch Virol | Analysis of cytokine production in a newly developed canine tracheal epithelial cell line infected with H3N3 canine influenza virus [PubMed: 25797196] |
J | Complexes of DNA with the Antimicrobial Peptide LL37 Augment NK Cell Functions by Inducing Type I Interferon Production from Circulating Monocytes and Plasmacytoid Predendritic Cells [PubMed: 26258404] |
Virus | PKR activation enhances replication of classical swine fever virus in PK-15 cells [PubMed: 25899421] |
PLoS One | siRNA Targeting the 2A pro Genomic Region Prevents Enterovirus 71 Replication In Vitro [Pubmed:26886455] |
Scientific Reports | Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4 [Pubmed:27090571] |
Front Microbiol | Innate Immune Responses in ALV-J Infected Chicks and Chickens with Hemangioma In Vivo [Pubmed:27252695] |
Canadian Journal of Physiology and Pharmacology | Chloroquine attenuates lipopolysaccharide-induced inflammatory responses through upregulation of USP25. [pubmed:28134560] |
International Journal of Molecular Medicine | Effects of IRF1 and IFN-β interaction on the M1 polarization of macrophages and its antitumor function [pubmed:27176664] |
International Journal of Clinical and Experimental Pathology | Host miR-146a promotes replication of human cytomegalovirus by suppressing type I IFN response in MRC-5 cells [files:ijcep0036479.pdf] |
Poultry Science | ALV-J strain SCAU-HN06 induces innate immune responses in chicken primary monocyte-derived macrophages [pubmed:27486255] |
Journal of Virology | Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. [pubmed:] |
Biochemical and Biophysical Research Communications | MicroRNA-548j inhibits type I interferon production by targeting ZBTB11 in patients with chronic hepatitis B [pubmed:28342861] |
Virology | The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection [pubmed:28988058] |
EMBO Journal | Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1‐caspase‐1 axis [Pubmed:30065070] |
Toxicology and applied pharmacology | Bisphenol A induced male germ cell apoptosis via IFNβ-XAF1-XIAP pathway in adult mice [Pubmed:30017639] |
Archives of Virology | MAVS induces a host cell defense to inhibit CSFV infection [Pubmed:29556776] |
Journal of virology | Inhibition of DNA-sensing pathway by Marek's disease virus VP23 protein through suppression of interferon regulatory factor 7 activation [Pubmed: 30518647] |
Veterinary Immunology and Immunopathology | Molecular cloning and functional characterization of porcine 2′, 5′-oligoadenylate synthetase 1b and its effect on infection with porcine reproductive and respiratory?… [Doi: 10.1016/j.vetimm.2019.01.003] |
Science Signaling | HIPK2 is necessary for type I interferon–mediated antiviral immunity [Doi: 10.1126/scisignal.aau4604] |
INTERNATIONAL MEDICAL RESEARCH | Evaluation of serum interferons in patients with age-related macular degeneration [Pubmed: 31007694] |
Veterinary Immunology and Immunopathology | Differential expression of type I interferon mRNA and protein levels induced by virulent Marek's disease virus infection in chickens [] |
International journal of biological macromolecules | Porcine FcγRIIb mediated PRRSV ADE infection through inhibiting IFN-β by cytoplasmic inhibitory signal transduction [Pubmed: 31284005] |
Journal of virology | Marek's Disease Virus RLORF4 Inhibits Type I Interferon Production by Antagonizing NF-κB Activation [Pubmed: 31243133] |
The Journal of Latvian Academy of Sciences | Serodiagnosis of Human Bocavirus 1 Infection among Hospitalised Children with Lower Respiratory Tract Infection in Latvia [] |
Cancer Medicine | The immunostimulatory effects and pro‐apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll‐like receptor 4 [Pubmed: 31218844] |
FASEB Journal | Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF 3 ubiquitination through recruiting OTUB 1 [] |
PLOS Pathogens | Avian oncogenic herpesvirus antagonizes the cGAS-STING DNA-sensing pathway to mediate immune evasion [Pubmed: 31539404] |
Autophagy | Induction of autophagy and suppression of type I IFN secretion by CSFV [Pubmed: 32160078] |
MOLECULAR IMMUNOLOGY | BVDV-1 induces interferon-beta gene expression through a pathway involving IRF1, IRF7, and NF-κB activation [Pubmed: 33053462] |
Autophagy | LDHB inhibition induces mitophagy and facilitates the progression of CSFV infection [Pubmed: 32924761] |
Arch Virol . | Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway [Pubmed: 32532134] |
Virulence | Determination of antiviral action of Long Non-coding RNA loc107051710 During Infectious Bursal Disease Virus Infection due to Enhancement of Interferon … [] |
bioRxiv | Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance [] |
Res Vet Sci | Open reading frame 5 protein of porcine circovirus type 2 induces RNF128 (GRAIL) which inhibits mRNA transcription of interferon-β in porcine epithelial cells [34416463] |
Eur J Immunol | Anti‐IFN‐α/‐ω neutralizing antibodies from COVID‐19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity [Pubmed:35419822] |
ResearchSquare | Chicken Intestinal Microbiota Modulation of Resistance to Nephropathogenic Infectious Bronchitis Virus Infection Through IFN-I [] |
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