胱天蛋白酶1(CASP1)单克隆抗体
Monoclonal Antibody to Caspase 1 (CASP1)
ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
- 编号MAB592Ra21
- 物种Rattus norvegicus (Rat,大鼠) 相同的名称,不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)-
- Ig亚型 IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原 -
- 缓冲液成份磷酸盐缓冲液(pH7.4,含有0.02% NaN3和50%甘油)
- 性状液体
- 浓度1mg/mL
- 且适物种-
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 688 ¥ 1604 ¥ 2292 ¥ 5730 ¥ 22920
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对CASP1的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别CASP1。
用法
免疫印迹:0.2-2µg/mL;1:500-5000
免疫组织化学:5-20µg/mL;1:50-200
免疫细胞化学:5-20µg/mL;1:50-200
最佳稀释倍数最终由用户决定。
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
编号 | 适用物种:Rattus norvegicus (Rat,大鼠) | 应用(仅供研究使用,不用于临床诊断!) |
APB592Ra01 | 胱天蛋白酶1(CASP1)活性蛋白 | Cell culture; Activity Assays. |
RPB592Ra01 | 胱天蛋白酶1(CASP1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB592Ra01 | 胱天蛋白酶1(CASP1)多克隆抗体 | WB; IHC; ICC; IP. |
LAB592Ra71 | 胱天蛋白酶1(CASP1)多克隆抗体(生物素标记) | WB; IHC; ICC. |
MAB592Ra21 | 胱天蛋白酶1(CASP1)单克隆抗体 | WB; IHC; ICC; IP. |
SEB592Ra | 胱天蛋白酶1(CASP1)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB592Ra | 胱天蛋白酶1(CASP1)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion [Pubmed:24816434] |
Fertil Steril | Inflammosome in the human endometrium: further step in the evaluation of the “maternal side” [PubMed: 26474737] |
PLoS One | Synthetic PreImplantation Factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response. [pubmed:28704412] |
Journal of Virology | NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination [Pubmed:29386291] |
Journal of Translational Medicine | Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation? [Pubmed:29665864] |
Reproductive Sciences | A role for the inflammasome in spontaneous labor at term [Pubmed:27852921] |
Journal of Virology | CHARACTERIZATION OF PORCINE NLRP3 INFLAMMASOME-MEDIATED INTERLEUKIN-1 BETA PRODUCTION IN RESPONSE TO INFLUENZA A VIRUSES [Pubmed: 29386291] |
ACTA Otorhinolaryngologica Italica | NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media [Pubmed: 30676848] |
American Journal of Reproductive Immunology | Effect of alpha lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women [Pubmed: 31148259] |
Taiwanese Journal of Obstetrics & Gynecology | Serum Caspase-1 levels in women with polycystic ovary syndrome [Pubmed: 32127139] |
Iranian Journal of Allergy, Asthma and Immunology | Increased Level of Caspase-1 in the Serum of Relapsing-remitting Multiple Sclerosis (RRMS) Patients [] |
ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES [] | |
Norwegian Journal of development of the International Science | CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER [] |
LIFE SCIENCES | The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation [34560082] |
Biol Reprod | The alarmin S100A12 causes sterile inflammation of the human chorioamniotic membranes and preterm birth and neonatal mortality in mice [34632484] |
J Mol Neurosci | TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury [Pubmed:35041191] |
Viruses | Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion [Pubmed:35062292] |
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