表皮生长因子受体(EGFR)单克隆抗体
Monoclonal Antibody to Epidermal Growth Factor Receptor (EGFR)
ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
- 编号MAA757Hu24
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)C7
- Ig亚型 IgG2b Kappa
- 纯化方式蛋白A + 蛋白G亲和纯化
- 标记物无标记物
- 免疫原 RPA757Hu02-表皮生长因子受体(EGFR)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性状液体
- 浓度1mg/ml
- 且适物种Sus scrofa; Porcine (Pig,猪)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 652 ¥ 1520 ¥ 2172 ¥ 5430 ¥ 21720
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对EGFR的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别EGFR。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) |
APA757Hu62 | 表皮生长因子受体(EGFR)活性蛋白 | Cell culture; Activity Assays. |
RPA757Hu01 | 表皮生长因子受体(EGFR)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APA757Hu61 | 表皮生长因子受体(EGFR)活性蛋白 | Cell culture; Activity Assays. |
EPA757Hu62 | 表皮生长因子受体(EGFR)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA757Hu02 | 表皮生长因子受体(EGFR)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA757Hu61 | 表皮生长因子受体(EGFR)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA757Hu06 | 表皮生长因子受体(EGFR)多克隆抗体 | WB; IHC; ICC; IP. |
PAA757Hu02 | 表皮生长因子受体(EGFR)多克隆抗体 | WB; IHC; ICC; IP. |
PAA757Hu01 | 表皮生长因子受体(EGFR)多克隆抗体 | WB; IHC; ICC; IP. |
FAA757Hu51 | 抗表皮生长因子受体(EGFR)多克隆抗体(别藻蓝蛋白标记) | FCM |
MAA757Hu27 | 表皮生长因子受体(EGFR)单克隆抗体 | WB; IHC; ICC; IP. |
MAA757Hu29 | 表皮生长因子受体(EGFR)单克隆抗体 | WB; IHC; ICC; IP. |
RAA757Hu21 | 表皮生长因子受体(EGFR)重组抗体 | WB; IF; ICC; IHC; IP; FCM. |
MAA757Hu21 | 表皮生长因子受体(EGFR)单克隆抗体 | WB; IHC; ICC; IP. |
MAA757Hu23 | 表皮生长因子受体(EGFR)单克隆抗体 | WB; IHC; ICC; IP. |
MAA757Hu24 | 表皮生长因子受体(EGFR)单克隆抗体 | WB; IHC; ICC; IP. |
MAA757Hu25 | 表皮生长因子受体(EGFR)单克隆抗体 | WB; IHC; ICC; IP. |
MAA757Hu22 | 表皮生长因子受体(EGFR)单克隆抗体 | WB; IHC |
SEA757Hu | 表皮生长因子受体(EGFR)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
HEA757Hu | 表皮生长因子受体(EGFR)检测试剂盒(酶联免疫吸附试验法,高敏型) | Enzyme-linked immunosorbent assay for Antigen Detection. |
AEA757Hu | 抗表皮生长因子受体抗体(Anti-EGFR)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antibody Detection. |
LMA757Hu | 表皮生长因子受体(EGFR)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
杂志 | 参考文献 |
Thoracic Cancer | Nimotuzumab combined with gemcitabine and cisplatin as second-line chemotherapy for advanced non-small-cell lung cancer [Wiley: source] |
J Cent Nerv Syst Dis.? | Increased Epidermal Growth Factor Receptor (EGFR) Associated with Hepatocyte Growth Factor (HGF) and Symptom Severity in Children with Autism … [Pubmed:25249767] |
Mol Cancer Ther | GC1118, an anti-EGFR antibody with a distinct binding epitope and superior inhibitory activity against high-affinity EGFR ligands [PubMed: 26586721] |
Cell Death Dis. | LINC01225 promotes occurrence and metastasis of hepatocellular carcinoma in an epidermal growth factor receptor-dependent pathway [Pubmed:26938303] |
analytica chimica acta | Microfluidic immunosensor based on mesoporous silica platform and CMK-3/poly-acrylamide-co-methacrylate of dihydrolipoic acid modified gold electrode for cancer biomarker detection. [pubmed:28335979] |
Talanta | EGFR detection in extracellular vesicles of breast cancer patients through immunosensor based on silica-chitosan nanoplatform [Doi: 10.1016/j.talanta.2018.10.016] |
Bioorganic Chemistry | Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers [Pubmed: 30665034] |
Journal of enzyme inhibition and medicinal chemistry | Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile [Pubmed: 30919701] |
Bioorganic Chemistry | Design and synthesis of new benzoxazole/benzothiazole-phthalimide hybrids as antitumor-apoptotic agents [] |
Bioorganic Chemistry | Synthesis and anticancer activity of bis-benzo [d][1, 3] dioxol-5-yl thiourea derivatives with molecular docking study [Pubmed: 31288134] |
Oxidative Medicine and Cellular Longevity | Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters … [Pubmed: 31737175] |
Neoplasia | Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine [Pubmed: 33212364] |
Association between Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung [] | |
Synthesis, EGFR-TK inhibition and anticancer activity of new quinoxaline derivatives [] | |
IMMUNOLOGIC RESEARCH | Humoral immune response to epidermal growth factor receptor in lung cancer [33495907] |
European Journal of Medicinal Chemistry | Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure¨Cactivity relationship and biological activity as potential antitumor and anticonvulsant agents [33545637] |
Journal of Molecular Structure | Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors [] |
ACS Appl Mater Interfaces | Emitter–Quencher Pair of Single Atomic Co Sites and Monolayer Titanium Carbide MXenes for Luminol Chemiluminescent Reactions [34914377] |
Bioorganic Chemistry | Discovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies [Pubmed:35219045] |
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