成纤维细胞生长因子21(FGF21)单克隆抗体
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)
- 编号MAC918Ra21
- 物种Rattus norvegicus (Rat,大鼠) 相同的名称,不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)-
- Ig亚型 IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原 -
- 缓冲液成份磷酸盐缓冲液(pH7.4,含有0.02% NaN3和50%甘油)
- 性状液体
- 浓度1mg/mL
- 且适物种-
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术,请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 720 ¥ 1680 ¥ 2400 ¥ 6000 ¥ 24000
- 欲了解实际交易价格和更多情况,请与当地经销商联系!
特异性
该抗体是针对FGF21的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别FGF21。
用法
免疫印迹:0.2-2µg/mL;1:500-5000
免疫组织化学:5-20µg/mL;1:50-200
免疫细胞化学:5-20µg/mL;1:50-200
最佳稀释倍数最终由用户决定。
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
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编号 | 适用物种:Rattus norvegicus (Rat,大鼠) | 应用(仅供研究使用,不用于临床诊断!) |
APC918Ra01 | 成纤维细胞生长因子21(FGF21)活性蛋白 | Cell culture; Activity Assays. |
RPC918Ra02 | 成纤维细胞生长因子21(FGF21)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
EPC918Ra61 | 成纤维细胞生长因子21(FGF21)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APC918Ra61 | 成纤维细胞生长因子21(FGF21)活性蛋白 | Cell culture; Activity Assays. |
RPC918Ra01 | 成纤维细胞生长因子21(FGF21)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAC918Ra02 | 成纤维细胞生长因子21(FGF21)多克隆抗体 | WB; IHC; ICC; IP. |
PAC918Ra01 | 成纤维细胞生长因子21(FGF21)多克隆抗体 | WB; IHC; ICC; IP. |
MAC918Ra21 | 成纤维细胞生长因子21(FGF21)单克隆抗体 | WB; IHC; ICC; IP. |
SEC918Ra | 成纤维细胞生长因子21(FGF21)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
CEC918Ra | 成纤维细胞生长因子21(FGF21)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
WEC918Ra | 成纤维细胞生长因子21(FGF21)检测试剂盒(酶联免疫吸附试验法,宽范围) | Enzyme-linked immunosorbent assay for Antigen Detection. |
CCC918Ra | 成纤维细胞生长因子21(FGF21)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
LMC918Ra | 成纤维细胞生长因子21(FGF21)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
PGC918Ra01 | 成纤维细胞生长因子21(FGF21)引物对 | PCR |
参考文献
杂志 | 参考文献 |
Lipids in Health and Disease | Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs [Lipidworld: source] |
Endocrinology | Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression [Endocrine:Source] |
Biochemical and Biophysical Research Communications | Alpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH [Pubmed:25449271] |
Free Radic Biol Med | Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α pathway [PubMed: 25843656] |
Journal of diabetes and its complications | Associations between FGF21, osteonectin and bone turnover markers in type 2 diabetic patients with albuminuria. [pubmed:27916484] |
American journal of the medical sciences | Association of Bone Metabolic Markers With Diabetic Retinopathy and Diabetic Macular Edema in Elderly Chinese Individuals With Type 2 Diabetes Mellitus [pubmed:29078839] |
Frontiers in Physiology | Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21 [Pubmed:29593555] |
Некоторые аспекты транспортной системы метаболизма железа в зависимости от степени синдрома перегрузки железом у детей с хроническим … [] | |
Physiol Res | Fibroblast growth factor 21 (FGF21) in children and adolescents with chronic kidney disease. [Pubmed: 32469231] |
Chinese Journal of Osteoporosis | 2 型糖尿病患者血清FGF21, 骨连结蛋白和骨转换指标的相关性研究. [] |
Sci Rep | Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats [33833309] |
Nutrients | The Speed of Ingestion of a Sugary Beverage Has an Effect on the Acute Metabolic Response to Fructose [] |
Medicine (Baltimore) | Association of serum fibroblast growth factor 21 with kidney function in a population-based Chinese cohort [34918690] |
Annals of Agricultural and Environmental Medicine | Oxidative stress-induced growth inhibitor 1 in alcohol-induced liver cirrhosis [34969228] |
J Magn Reson Imaging | Water Specific MRI T1 Mapping for Evaluating Liver Inflammation Activity Grades in Rats With Methionine‐Choline‐Deficient Diet‐Induced Nonalcoholic Fatty Liver … [Pubmed:35212074] |
Lab Invest | Fibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury [Pubmed:35488034] |
Molecular Biology Reports | Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling … [Pubmed:35585377] |
High Circulating Fibroblast Growth Factor-21 Levels as a Prognostic Marker in Fatty Pancreas Patients [] |
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