核因子κB受体激活因子配体(RANkL)单克隆抗体
Monoclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
CD254; TNFSF11; ODF; OPGL; TRANCE; HRANKL2; SOdf; Tumor Necrosis Factor(ligand)superfamily Member 11; TNF-related activation-induced cytokine
- 编号MAA855Ra25
- 物种Rattus norvegicus (Rat，大鼠) 相同的名称，不同的物种。
- 来源单抗制备
- 宿主小鼠
- 效价(克隆号)C14
- Ig亚型 IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原 -
- 缓冲液成份磷酸盐缓冲液（pH7.4,含有0.02% NaN3和50%甘油）
- 性状液体
- 浓度1mg/mL
- 且适物种Homo sapiens (Human，人)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 暂无报价 暂无报价 暂无报价 暂无报价 暂无报价
- 欲了解实际交易价格和更多情况，请与当地经销商联系!
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产品包装(模拟)
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产品包装(模拟)
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AF488 staining on IF;
Sample: MCF7 cell
Primary Ab: 20µg/ml Mouse Anti-Rat RANkL Antibody
Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu11)
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通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对RANkL的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别RANkL。
用法
Western blotting: 0.2-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| APA855Ra61 | 核因子κB受体激活因子配体(RANkL)活性蛋白 | Cell culture; Activity Assays. |
| RPA855Ra01 | 核因子κB受体激活因子配体(RANkL)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA855Ra01 | 核因子κB受体激活因子配体(RANkL)多克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra24 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra26 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra22 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra23 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra21 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra25 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra27 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra28 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| MAA855Ra29 | 核因子κB受体激活因子配体(RANkL)单克隆抗体 | WB; IHC; ICC; IP. |
| LAA855Ra76 | 核因子κB受体激活因子配体(RANkL)单克隆抗体(生物素标记) | WB; IHC; ICC. |
| SEA855Ra | 核因子κB受体激活因子配体(RANkL)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA855Ra | 核因子κB受体激活因子配体(RANkL)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMA855Ra | 核因子κB受体激活因子配体(RANkL)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
| PSA855Ra01 | 核因子κB受体激活因子配体(RANkL)抗体对 | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
| KSA855Ra01 | 核因子κB受体激活因子配体(RANkL)检测试剂盒DIY材料(酶联免疫吸附试验法) | Main materials for "Do It (ELISA Kit) Yourself". |
参考文献
| 杂志 | 参考文献 |
| Archives of Oral Biology | Compressive stress induced the up-regulation of M-CSF, RANKL, TNF-α expression and the down-regulation of OPG expression in PDL cells via the integrin-FAK pathway [ScienceDirect: S0003996912003998] |
| PLOS One | Adipokines in Psoriatic Arthritis Patients: The Correlations with Osteoclast Precursors and Bone Erosions [PubMed: PMC3483160] |
| Arthritis Research&Therapy | Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes [PubMed: PMC3672788] |
| International Journal of Oral and Maxillofacial Surgery | The effects of chronic zoledronate usage on the jaw and long bones evaluated using RANKL and osteoprotegerin levels in an animal model [Pubmed: 23522850] |
| AGE | Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells [Pubmed: 24687841] |
| Food Science & Nutrition | Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7 [Onlinelibrary: fsn3.109] |
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| Journal of Investigative Surgery | Effect of Nicotine on RANKL and OPG and Bone Mineral Density [Pubmed:24830656] |
| Int J Mol Med. | Effects of icariin on the regulation of the OPG?RANKL?RANK system are mediated through the MAPK pathways in IL?1β?stimulated human SW1353 chondrosarcoma … [Pubmed:25270538] |
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| Epilepsy Research | The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats [pubmed:27838501] |
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| Sci Rep. | Sprint Interval Training Induces A Sexual Dimorphism but does not Improve Peak Bone Mass in Young and Healthy Mice. [pubmed:28303909] |
| Sci Rep. | Skeletal Site-specific Effects of Zoledronate on in vivo Bone Remodeling and in vitro BMSCs Osteogenic Activity. [pubmed:28139685] |
| Biomedicine & Pharmacotherapy | Anti-osteoporotic effects of an antidepressant tianeptine on ovariectomized rats [S0753332216322752] |
| BMJ Journals | SAT0003 The Role of 12/15-Lipoxygenase in The Pathogenesis of Osteoporosis in Mice [content:75] |
| Japanese Society for Bone and Mineral Research | Allogeneic yet major histocompatibility complex‑matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced trabecular bone [article:10.1007] |
| ONCOLOGY LETTERS | Assessment of bone metabolism and biomechanical properties of the femur, following treatment with anastrozole and letrozole in an experimental model of menopause [ol.2017.6596] |
| Journal of Clinical Periodontology | Peroxisome proliferator‐activated receptor γ plays dual roles on experimental periodontitis in rats [Pubmed:29574908] |
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| Journal of Periodontal Research | Improved RANKL expression and osteoclastogenesis induction of CD27+ CD38− memory B cells: A link between B cells and alveolar bone damage in periodontitis [Pubmed: 30346027] |
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| Bone | Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process [Pubmed: 30797058] |
| Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | Evaluation of therapeutic effects of teriparatide in a rat model of zoledronic acid-induced bisphosphonate-related osteonecrosis [] |
| Rheumatology International | Comparison of RANKL expression, inflammatory markers, and cardiovascular risk in patients with acute coronary syndrome with and without rheumatoid arthritis [Pubmed: 31297563] |
| World Journal of Pediatrics | Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis [Pubmed: 31641939] |
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| Br J Haematol | Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment [Pubmed:34954822] |
| Biomed Pharmacother | Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis [Pubmed:35453007] |
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